Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Danielle N Renner"'
Autor:
Courtney S Malo, Danielle N Renner, April M Huseby Kelcher, Fang Jin, Michael J Hansen, Kevin D Pavelko, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0162064 (2016)
Virus vector-based vaccination against tumor-specific antigens remains a promising therapeutic approach to overcome the immune suppressive tumor microenvironment. However, the extent that the desired CD8 T cell response against the targeted tumor ant
Externí odkaz:
https://doaj.org/article/1dfc8de581a0428bab4e518a13d107f1
Autor:
Danielle N Renner, Fang Jin, Adam J Litterman, Alexis J Balgeman, Lisa M Hanson, Jeffrey D Gamez, Michael Chae, Brett L Carlson, Jann N Sarkaria, Ian F Parney, John R Ohlfest, Istvan Pirko, Kevin D Pavelko, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125565 (2015)
Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence. It is therefore critical to establish experimental model systems and develop therapeutic appr
Externí odkaz:
https://doaj.org/article/90232fcf3569472f97f5f1698045350b
Autor:
Brendan K Reed, Laura B Chopp, Courtney S Malo, Danielle N Renner, Virginia S Van Keulen, Megan A Girtman, Wendy N Nevala, Kevin D Pavelko, Diana Gil, Adam G Schrum, Aaron J Johnson, Larry R Pease
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137984 (2015)
Antigen-specific T cell responses can be visualized using MHC:peptide multimers. In cases where robust T cell controls are not readily available to assess the integrity of multimer reagents prior to analyzing limited sample, the ability to assess the
Externí odkaz:
https://doaj.org/article/1fb448f2255f452cad3fed8f44b99cae
An elite controller of picornavirus infection targets an epitope that is resistant to immune escape.
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94332 (2014)
The emergence of novel viral pathogens can lead to devastating consequences in the infected population. However, on occasion, rare hyper-responsive elite controllers are able to mount a protective primary response to infection and clear the new patho
Externí odkaz:
https://doaj.org/article/6e2ccd59f6044b0fab2cda0383b561a8
Autor:
Isobel A Scarisbrick, Benjamin Epstein, Beth A Cloud, Hyesook Yoon, Jianmin Wu, Danielle N Renner, Sachiko I Blaber, Michael Blaber, Alexander G Vandell, Alexandra L Bryson
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18376 (2011)
Kallikrein 6 (KLK6) is a newly identified member of the kallikrein family of secreted serine proteases that prior studies indicate is elevated at sites of central nervous system (CNS) inflammation and which shows regulated expression with T cell acti
Externí odkaz:
https://doaj.org/article/cb202fbf74964e07b536e229ae68bf9d
Autor:
Aaron J. Johnson, Matthew A. Huggins, Heather M. A. Tolcher, Fang Jin, Larry R. Pease, Danielle N. Renner, Michael J. Hansen, Emma N. Goddery, Courtney S. Malo, Kevin D. Pavelko
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The contribution of antigen-presenting cell (APC) types in generating CD8+ T cell responses in the central nervous system (CNS) is not fully defined, limiting the development of vaccines and understanding of immune-mediated neuropathology. Here, we g
Autor:
Courtney S, Malo, Matthew A, Huggins, Emma N, Goddery, Heather M A, Tolcher, Danielle N, Renner, Fang, Jin, Michael J, Hansen, Larry R, Pease, Kevin D, Pavelko, Aaron J, Johnson
Publikováno v:
Nature Communications
The contribution of antigen-presenting cell (APC) types in generating CD8+ T cell responses in the central nervous system (CNS) is not fully defined, limiting the development of vaccines and understanding of immune-mediated neuropathology. Here, we g
Autor:
Kevin D. Pavelko, Danielle N. Renner, Fang Jin, Ian F. Parney, Courtney S. Malo, Aaron J. Johnson
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 13(1)
The addition of antiangiogenic therapy to the standard-of-care treatment regimen for recurring glioblastoma has provided some clinical benefits while also delineating numerous caveats, prompting evaluation of the elicited alterations to the tumor mic
Autor:
Jeffrey D. Gamez, John R. Ohlfest, Ian F. Parney, Lisa M. Hanson, Istvan Pirko, Fang Jin, Danielle N. Renner, Kevin D. Pavelko, Jann N. Sarkaria, Aaron J. Johnson, Alexis J. Balgeman, Brett L. Carlson, Michael Chae, Adam J. Litterman
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125565 (2015)
PLoS ONE
PLoS ONE
Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence. It is therefore critical to establish experimental model systems and develop therapeutic appr
A CD8 T-Cell Epitope Variant Enhances Immune Targeting to a Recombinant Picornavirus Vaccine Antigen
Recombinant virus vaccines are often less effective due to immunodominant responses against endogenous vector antigens. However, the use of small RNA virus vectors provides an opportunity to limit host exposure to endogenous virus antigens and focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcda707d51521292a8b93780a701f86
https://europepmc.org/articles/PMC4150375/
https://europepmc.org/articles/PMC4150375/