Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Danielle N Gallagher"'
Autor:
Jihyun Choi, Muwen Kong, Danielle N Gallagher, Kevin Li, Gabriel Bronk, Yiting Cao, Eric C Greene, James E Haber
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010056 (2022)
Using budding yeast, we have studied Rad51-dependent break-induced replication (BIR), where the invading 3' end of a site-specific double-strand break (DSB) and a donor template share 108 bp of homology that can be easily altered. BIR still occurs ab
Externí odkaz:
https://doaj.org/article/9b7086fc651b42c1a94cc5e31d1434a4
Autor:
Danielle N Gallagher, Nhung Pham, Annie M Tsai, Nicolas V Janto, Jihyun Choi, Grzegorz Ira, James E Haber
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1008689 (2020)
The Rad51/RecA family of recombinases perform a critical function in typical repair of double-strand breaks (DSBs): strand invasion of a resected DSB end into a homologous double-stranded DNA (dsDNA) template sequence to initiate repair. However, rep
Externí odkaz:
https://doaj.org/article/69ec050854aa4461818f118bd5822bc8
Autor:
James E. Haber, Danielle N. Gallagher
Publikováno v:
Current Genetics. 67:747-753
DNA double-strand breaks (DSBs) pose a serious hazard for the stability of the genome. CRISPR-Cas9-mediated gene editing intentionally creates a site-specific DSB to modify the genomic sequence, typically from an introduced single-stranded DNA donor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdaed5d3856f32c4fc2cd84cc2d27627
https://doi.org/10.1007/s00294-021-01186-z
https://doi.org/10.1007/s00294-021-01186-z
Autor:
Danielle N, Gallagher, James E, Haber
Publikováno v:
Current genetics. 67(5)
DNA double-strand breaks (DSBs) pose a serious hazard for the stability of the genome. CRISPR-Cas9-mediated gene editing intentionally creates a site-specific DSB to modify the genomic sequence, typically from an introduced single-stranded DNA donor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f659f16b43eec3721d3c9e7b25c98db5
https://pubmed.ncbi.nlm.nih.gov/33881574
https://pubmed.ncbi.nlm.nih.gov/33881574
Autor:
James E. Haber, Danielle N. Gallagher
CRISPR/Cas9-mediated gene editing may involve nonhomologous end-joining to create various insertion/deletions (indels) or may employ homologous recombination to modify precisely the target DNA sequence. Our understanding of these processes has been g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d7d25608a1714007b5ec4754298a03
https://europepmc.org/articles/PMC5835394/
https://europepmc.org/articles/PMC5835394/
