Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Danielle Morse"'
Autor:
Avignat S Patel, Jin Woo Song, Sarah G Chu, Kenji Mizumura, Juan C Osorio, Ying Shi, Souheil El-Chemaly, Chun Geun Lee, Ivan O Rosas, Jack A Elias, Augustine M K Choi, Danielle Morse
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121246 (2015)
Epithelial cell death is a major contributor to fibrogenesis in the lung. In this study, we sought to determine the function of mitochondria and their clearance (mitophagy) in alveolar epithelial cell death and fibrosis.We studied markers of mitochon
Externí odkaz:
https://doaj.org/article/73226e61a6ee4f418966c2cdc041e47f
Autor:
Casey A. Maguire, Johannes C. van der Mijn, Marja H. Degeling, Danielle Morse, Bakhos A. Tannous
Publikováno v:
Molecular Imaging, Vol 11 (2012)
Luciferases have proven to be useful tools in advancing our understanding of biologic processes. Having a multitude of bioluminescent reporters with different properties is highly desirable. We characterized codon-optimized thermostable green- and re
Externí odkaz:
https://doaj.org/article/3e21215b046944be810bd86f0d92d9f5
Autor:
Avignat S Patel, Ling Lin, Alexander Geyer, Jeffrey A Haspel, Chang Hyeok An, Jiaofei Cao, Ivan O Rosas, Danielle Morse
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41394 (2012)
BACKGROUND:Autophagy is a basic cellular homeostatic process important to cell fate decisions under conditions of stress. Dysregulation of autophagy impacts numerous human diseases including cancer and chronic obstructive lung disease. This study inv
Externí odkaz:
https://doaj.org/article/9e0d2ba361b24beb894de2e4d58cc1c2
Autor:
Ivan O. Rosas, Bernadette R. Gochuico, Danielle Morse, Hao Wang, Souheil El-Chemaly, Ying Shi, Cristobal Risquez, Juan C. Osorio, Ye Cui
Publikováno v:
Molecular Medicine. 20:120-134
Vascular endothelial growth factor (VEGF)-D, a member of the VEGF family, induces both angiogenesis and lymphangiogenesis by activating VEGF receptor-2 (VEGFR-2) and VEGFR-3 on the surface of endothelial cells. Transforming growth factor (TGF)-β1 ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8619362bd2c5a6bf2aa0d75574d7783f
https://doi.org/10.2119/molmed.2013.00123
https://doi.org/10.2119/molmed.2013.00123
Autor:
Jeffrey A. Haspel, Xiaomeng Tang, Cristobal Risquez, Andrew J. Goodwin, Ying Shi, Marc G. Wathelet, Isis E. Fernandez, Stefan W. Ryter, Juan C. Osorio, Bernadette R. Gochuico, Yuanyuan Shi, Guoying Yu, Eric M. Billings, Naftali Kaminski, Danielle Morse, Avignat Patel, Ivan O. Rosas
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 188:831-841
Alveolar transforming growth factor (TGF)-β1 signaling and expression of TGF-β1 target genes are increased in patients with idiopathic pulmonary fibrosis (IPF) and in animal models of pulmonary fibrosis. Internalization and degradation of TGF-β re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8903178ef92bcf298700d504ddf977f1
https://doi.org/10.1164/rccm.201303-0434oc
https://doi.org/10.1164/rccm.201303-0434oc
Autor:
Tsuneo Yamashiro, David A. Lynch, MeiLan K. Han, George R. Washko, Ivan O. Rosas, Hiroto Hatabu, Mizuki Nishino, James C. Ross, Augustine M.K. Choi, Alejandro A. Diaz, Edwin K. Silverman, Gary M. Hunninghake, Avignat Patel, Jin Fu Xu, Carolyn E. Come, Raúl San José Estépar, Hui Ping Li, Fernando J. Martinez, Danielle Morse, Kiichi Nakahira, Blanca E. Himes, Stefan W. Ryter, James D. Crapo, Katherine D'Aco, Jie Ming Qu, Yuka Okajima, Isis E. Fernandez
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 185:547-556
Rationale: The role of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) in the development or progression of interstitial lung disease (ILD) is controversial.Objectives: To evaluate the association between statin use and ILD.Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d09f249716d6e2b203a1ba61dac34ad3
https://doi.org/10.1164/rccm.201108-1574oc
https://doi.org/10.1164/rccm.201108-1574oc
Publikováno v:
Journal of Analytical Sciences, Methods and Instrumentation. :5-12
For the analysis of microRNA, a common approach is to first extract microRNA from cellular samples prior to any specific microRNA detection. Thus, it is important to determine the quality and yield of extracted microRNA. In this study, solid-phase ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80fab379d65fc4f269c9225c0c903ce
https://doi.org/10.4236/jasmi.2012.21002
https://doi.org/10.4236/jasmi.2012.21002
Autor:
Bakhos A. Tannous, Miguel Sena-Esteves, Gary Hsich, Xandra O. Breakefield, Ching-Hsuan Tung, Nikolaos C. Deliolanis, Danielle Morse, Lisa Pike
Publikováno v:
Gene therapy
Gene Ther. 18, 1173-1178 (2011)
Gene Ther. 18, 1173-1178 (2011)
Adeno-associated virus (AAV) mediated gene replacement for lysosomal disorders have been spurred by the ability of some serotypes to efficiently transduce neurons in the brain and by the ability of lysosomal enzymes to cross-correct among cells. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92b9a7a650c273f5bfc59bf2b4eba05
https://doi.org/10.1038/gt.2011.118
https://doi.org/10.1038/gt.2011.118
Autor:
Augustine M.K. Choi, Danielle Morse, Zhihong Zhou, Sean Alber, Liang Zheng, Ling Lin, Simon C. Watkins, Naftali Kaminski
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 41:85-92
Carbon monoxide (CO) is a biologically active molecule produced in the body by the stress-inducible enzyme, heme oxygenase. We have previously shown that CO suppresses fibrosis in a murine bleomycin model. To investigate the mechanisms by which CO op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f79740d97cd7b6225e48b9e32f60d8
https://doi.org/10.1165/rcmb.2007-0401oc
https://doi.org/10.1165/rcmb.2007-0401oc
Publikováno v:
Free Radical Biology and Medicine. 47:1-12
Increases in cell death by programmed (i.e., apoptosis, autophagy) or nonprogrammed mechanisms (i.e., necrosis) occur during tissue injury and may contribute to the etiology of several pulmonary or vascular disease states. The low-molecular-weight st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757a80d4f6352e6562167cc7427addb5
https://doi.org/10.1016/j.freeradbiomed.2009.04.007
https://doi.org/10.1016/j.freeradbiomed.2009.04.007