Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Danielle Maeser"'
Publikováno v:
BioMedInformatics, Vol 4, Iss 2, Pp 1363-1383 (2024)
As artificial intelligence (AI) integrates within the intersecting domains of healthcare and computational biology, developing interpretable models tailored to medical contexts is met with significant challenges. Explainable AI (XAI) is vital for fos
Externí odkaz:
https://doaj.org/article/b455091d640b4e438bf515c6556b812a
Autor:
Mei-Chi Su, Adam M. Lee, Weijie Zhang, Danielle Maeser, Robert F. Gruener, Yibin Deng, R. Stephanie Huang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 569 (2024)
Metastatic castration-resistant prostate cancer (mCRPC) remains a deadly disease due to a lack of efficacious treatments. The reprogramming of cancer metabolism toward elevated glycolysis is a hallmark of mCRPC. Our goal is to identify therapeutics s
Externí odkaz:
https://doaj.org/article/31978d13847a47d3bf3c457677a39a20
Autor:
Robert Galvin, Julia Nikrad, Tyler Jubenville, Danielle Maeser, Robert Gruener, Sampreeti Jena, Christopher Moertel, David Largaspaeda, R Stephanie Huang
Publikováno v:
Neuro-Oncology. 24:i84-i85
Central nervous system tumors account for the most childhood cancer mortality. Immunotherapies have made major contributions to treat adult cancers, but application of immunotherapy for childhood brain tumors has been limited, in part due to the uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070d3d3e0d5ec25f46e09297b73ccf56
https://doi.org/10.1093/neuonc/noac079.308
https://doi.org/10.1093/neuonc/noac079.308
Publikováno v:
Brief Bioinform
Cell line drug screening datasets can be utilized for a range of different drug discovery applications from drug biomarker discovery to building translational models of drug response. Previously, we described three separate methodologies to (1) corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3571d566a5b043f85a5fe7c5af0c2591
https://pubmed.ncbi.nlm.nih.gov/34260682
https://pubmed.ncbi.nlm.nih.gov/34260682
Autor:
Danielle Maeser, Shernan G. Holtan, Christopher Staley, Tauseef Ur Rehman, Alexander Khoruts, Daniel J. Weisdorf, Maryam Ebadi, Armin Rashidi, Thomas Kaiser
Publikováno v:
British Journal of Haematology. 189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681adc301b952927f89123f101965023
https://doi.org/10.1111/bjh.16509
https://doi.org/10.1111/bjh.16509
Publikováno v:
Neuro-Oncology Advances. 3:ii15-ii15
Therapy for pediatric central nervous system (CNS) malignancies can be toxic, and outcomes are suboptimal. Immunotherapy holds promise as a therapeutic avenue, but the poorly understood microenvironment limits its application. The Children’s Brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac1ba816ebd9a0873aa2a3bb5a60897
https://doi.org/10.1093/noajnl/vdab070.062
https://doi.org/10.1093/noajnl/vdab070.062
Autor:
Tomoyuki Koga, Stephanie R. Huang, Frank B. Furnari, Robert Galvin, Robert F. Gruener, David A. Largaespada, Clark C. Chen, Danielle Maeser
Publikováno v:
Cancer Research. 81:1300-1300
Glioblastoma (GBM) is a debilitating disease associated with poor prognosis and a limited response to therapies. At present, patients receive chemotherapy with temozolomide, following radiation therapy and surgery; however, none of the treatments are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a53811dae516e188867dd86b92847c1a
https://doi.org/10.1158/1538-7445.am2021-1300
https://doi.org/10.1158/1538-7445.am2021-1300
Publikováno v:
Neuro-Oncology
Therapy for pediatric central nervous system (CNS) malignancies can be toxic, and outcomes are suboptimal. Immunotherapy holds promise as a therapeutic avenue, but one of the challenges in its application is the poorly understood microenvironment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b9e991ca7e1aa0684d2592fefe39f2
http://europepmc.org/articles/PMC8168154
http://europepmc.org/articles/PMC8168154