Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Danielle M. Stacy"'
Autor:
Andrew G. Palmer, Jean-Michel Ané, Helen E. Blackwell, Arijit Mukherjee, Danielle M. Stacy, Stephen Lazar
Publikováno v:
ChemBioChem. 17:2199-2205
Density-dependent phenotypic switching in bacteria, the phenomenon of quorum sensing (QS), is instrumental in many pathogenic and mutualistic behaviors. In many Gram-negative bacteria, QS is regulated by N-acylated-l-homoserine lactones (AHLs). Synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1fc37575fc35460f02787da3c8484f
https://doi.org/10.1002/cbic.201600373
https://doi.org/10.1002/cbic.201600373
Autor:
Adam H. Broderick, David M. Lynn, Helen E. Blackwell, Yftah Tal-Gan, Danielle M. Stacy, Michael J. Kratochvil
Publikováno v:
Advanced Healthcare Materials. 3:97-105
Staphylococcus aureus is a major human pathogen responsible for a variety of life-threatening infections. The pathogenicity of this organism is attributed to its ability to produce a range of virulence factors and toxins, including the superantigen t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0633a39dbec3ab2c5bc2e097d4ac7de6
https://doi.org/10.1002/adhm.201300119
https://doi.org/10.1002/adhm.201300119
Publikováno v:
ACS Chemical Biology. 7:1719-1728
Many bacterial pathogens use quorum sensing (QS) to control virulence. As a result, the development of methods to intercept QS has attracted significant interest as a potential anti-infective therapy. Acinetobacter baumannii has emerged as a pan-drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f29864c1069d5afd38267b390b23c34
https://doi.org/10.1021/cb300351x
https://doi.org/10.1021/cb300351x
Publikováno v:
Chemical communications (Cambridge, England). 50(23)
We report the first N-methyl and peptoid residue scans of a full-length autoinducing peptide (AIP), AIP-III, used by Staphylococcus aureus for quorum sensing (QS). Biological evaluation of these AIP-III analogues uncovered new features of the AIP-III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17135d33bc42e8f3fd367bd35b2879eb
https://pubmed.ncbi.nlm.nih.gov/24509706
https://pubmed.ncbi.nlm.nih.gov/24509706
Autor:
Jacob W. Brummond, Sebastian Thordal Le Quement, Tim Tolker-Nielsen, Helen E. Blackwell, Danielle M. Stacy, Janie Regitse Waël Clausen, Michael Givskov, Casper Lykke Hansen, Thomas E. Nielsen
Publikováno v:
Organicbiomolecular chemistry. 11(6)
Many bacterial species are capable of assessing their local population densities through a cell-cell signaling mechanism termed quorum sensing (QS). This intercellular communication process is mediated by small molecule or peptide ligands and their c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fee729fad51d4a66a4b8503d3b7274
https://pubmed.ncbi.nlm.nih.gov/23258305
https://pubmed.ncbi.nlm.nih.gov/23258305
Publikováno v:
Organic letters. 10(12)
We report the design and synthesis of macrocyclic peptide-peptoid hybrids (peptomers) as analogs of autoinducing peptide I (AIP-I) from Staphylococcus aureus. Our solid-phase synthetic route includes efficient microwave-assisted reactions and a tande
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f569f21f5f950e3143c8083dfe3f1a
https://pubmed.ncbi.nlm.nih.gov/18476747
https://pubmed.ncbi.nlm.nih.gov/18476747
Publikováno v:
Organic Letters; May2008, Vol. 10 Issue 12, p2329-2332, 4p