Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Danielle M. Greenawalt"'
Autor:
Michael J. Schell, Mingli Yang, Jamie K. Teer, Fang Yin Lo, Anup Madan, Domenico Coppola, Alvaro N. A. Monteiro, Michael V. Nebozhyn, Binglin Yue, Andrey Loboda, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Timothy J. Yeatman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
APC is a well-known tumour suppressor that is frequently inactivated in colorectal cancer. Here, the authors sequence more than 1000 cancer genes in 468 colorectal cancers and show that mutation signatures can be used to classify the tumours and that
Externí odkaz:
https://doaj.org/article/33d97e94867e429f930222ed4bd1a79a
Autor:
Robert W. Wilkinson, Simon J. Dovedi, Ross Stewart, Viia Valge-Archer, Michelle Morrow, James A. Harper, Hazel Jones, Matthew McCourt, Brandon W. Higgs, Philip Brohawn, Jane Coates Ulrichsen, Amanda Watkins, Judith Anderton, Danielle Marcus, Luciano Pacelli, Stefanie Mullins, Rebecca Leyland, Miika J. Ahdesmaki, Danielle M. Greenawalt, Dennis Y.Q. Wang, Jens-Oliver Koopmann, Richard C.A. Sainson, John E. Prime, Suzanne I.S. Mosely
Murine syngeneic tumor models are critical to novel immuno-based therapy development, but the molecular and immunologic features of these models are still not clearly defined. The translational relevance of differences between the models is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcb199105c771e6b82b33f00095d352
https://doi.org/10.1158/2326-6066.c.6548411.v1
https://doi.org/10.1158/2326-6066.c.6548411.v1
Autor:
Robert W. Wilkinson, Simon J. Dovedi, Ross Stewart, Viia Valge-Archer, Michelle Morrow, James A. Harper, Hazel Jones, Matthew McCourt, Brandon W. Higgs, Philip Brohawn, Jane Coates Ulrichsen, Amanda Watkins, Judith Anderton, Danielle Marcus, Luciano Pacelli, Stefanie Mullins, Rebecca Leyland, Miika J. Ahdesmaki, Danielle M. Greenawalt, Dennis Y.Q. Wang, Jens-Oliver Koopmann, Richard C.A. Sainson, John E. Prime, Suzanne I.S. Mosely
Supplementary Figure S1: Summary of experiments Supplementary Figure S2: Gating strategy Supplementary Figure S3:Profiling by array CGH, whole-exome and targeted sequencing Supplementary Figure S4: Comparison of mutational profiles of murine syngenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f963acbe001e8dcef590d845d2ff257
https://doi.org/10.1158/2326-6066.22537352.v1
https://doi.org/10.1158/2326-6066.22537352.v1
Autor:
Robert W. Wilkinson, Simon J. Dovedi, Ross Stewart, Viia Valge-Archer, Michelle Morrow, James A. Harper, Hazel Jones, Matthew McCourt, Brandon W. Higgs, Philip Brohawn, Jane Coates Ulrichsen, Amanda Watkins, Judith Anderton, Danielle Marcus, Luciano Pacelli, Stefanie Mullins, Rebecca Leyland, Miika J. Ahdesmaki, Danielle M. Greenawalt, Dennis Y.Q. Wang, Jens-Oliver Koopmann, Richard C.A. Sainson, John E. Prime, Suzanne I.S. Mosely
Supplementary dataset containing raw data from targeted sequencing, whole exome sequencing, array CGH and transcriptomic analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94215efbd254285ab59554f7efa849cb
https://doi.org/10.1158/2326-6066.22537355
https://doi.org/10.1158/2326-6066.22537355
Autor:
Wayne A. Phillips, Robert J. S. Thomas, Daryl Lim Joon, Andrew Bui, Michael Chao, Joe Tjandra, Rodney J. Hicks, William K. Murray, Christopher A. Dow, Jason Ellul, Alexander G. Heriot, Danielle M. Greenawalt, Cuong P. Duong, Kate H. Brettingham-Moore
Supplementary Table S1 from Pretreatment Transcriptional Profiling for Predicting Response to Neoadjuvant Chemoradiotherapy in Rectal Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497112a5fd9dac928f5fc52262c793ca
https://doi.org/10.1158/1078-0432.22442087.v1
https://doi.org/10.1158/1078-0432.22442087.v1
Autor:
Wayne A. Phillips, Robert J. S. Thomas, Daryl Lim Joon, Andrew Bui, Michael Chao, Joe Tjandra, Rodney J. Hicks, William K. Murray, Christopher A. Dow, Jason Ellul, Alexander G. Heriot, Danielle M. Greenawalt, Cuong P. Duong, Kate H. Brettingham-Moore
Purpose: Patients presenting with locally advanced rectal cancer currently receive preoperative radiotherapy with or without chemotherapy. Although pathologic complete response is achieved for approximately 10% to 30% of patients, a proportion of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2355b839b8ae759a5d8c5f6cd6a7060
https://doi.org/10.1158/1078-0432.c.6518909.v1
https://doi.org/10.1158/1078-0432.c.6518909.v1
Autor:
Zhidong Tu, Mark P Keller, Chunsheng Zhang, Mary E Rabaglia, Danielle M Greenawalt, Xia Yang, I-Ming Wang, Hongyue Dai, Matthew D Bruss, Pek Y Lum, Yun-Ping Zhou, Daniel M Kemp, Christina Kendziorski, Brian S Yandell, Alan D Attie, Eric E Schadt, Jun Zhu
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003107 (2012)
Complex diseases result from molecular changes induced by multiple genetic factors and the environment. To derive a systems view of how genetic loci interact in the context of tissue-specific molecular networks, we constructed an F2 intercross compri
Externí odkaz:
https://doaj.org/article/0e466adc0d29468ab383a6fed2c47c6b
Autor:
Fang Yin Lo, Domenico Coppola, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Andrey Loboda, Mingli Yang, Anup Madan, Michael Nebozhyn, Timothy J. Yeatman, Binglin Yue, Jamie K. Teer, Alvaro N.A. Monteiro, Michael J. Schell
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Nature Communications
Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9179b0d5e6437b95c7fe28841f573a5d
https://doaj.org/article/33d97e94867e429f930222ed4bd1a79a
https://doaj.org/article/33d97e94867e429f930222ed4bd1a79a
Autor:
Jerrold M. Olefsky, Lee M. Kaplan, Yejun Tan, Dorothy D. Sears, Daniel M. Kemp, Mohammed Qatanani, Guanghui Hu, Wenqing Zhao, Danielle M. Greenawalt, Radu Dobrin
Publikováno v:
Diabetes
Obesity is associated with insulin resistance, a major risk factor for type 2 diabetes and cardiovascular disease. However, not all obese individuals are insulin resistant, which confounds our understanding of the mechanistic link between these condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa58f229e82d6432a9253d4b6b62625
http://europepmc.org/articles/PMC3581230
http://europepmc.org/articles/PMC3581230
Autor:
Frank B. Hu, Danielle M. Greenawalt, Justin Guinney, Hua Zhong, Lu Qi, Cynthia J. Girman, Xia Yang, Solveig K. Sieberts, Marilyn C. Cornelis
Publikováno v:
American Journal of Epidemiology. 176:423-430
Large-scale genome-wide association studies (GWAS) have identified over 40 genomic regions significantly associated with type 2 diabetes mellitus. However, GWAS results are not always straightforward to interpret, and linking these loci to meaningful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2448846585cfd0634f27c29ea6b0b70
https://doi.org/10.1093/aje/kws123
https://doi.org/10.1093/aje/kws123