Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Danielle M. Friedrichsen"'
Autor:
Erika M. Kwon, Laura McIntosh, Kerry Deutsch, Marta Janer, Leroy Hood, Danielle M. Friedrichsen-Karyadi, Janet L. Stanford, Bo Johanneson, Elaine A. Ostrander, Lori Iwasaki
Publikováno v:
The Prostate. 67:732-742
BACKGROUND. The Seattle-based PROGRESS study was started in 1995 to ascertain hereditary prostate cancer (HPC) families for studies of genetic susceptibility. Subsequent studies by several research groups, including our own, suggest that HPC is a gen
Autor:
Lee Hood, Kerry Deutsch, Brandon L. Pierce, Melissa A. Austin, Elaine A. Ostrander, Laura McIntosh, Danielle M. Friedrichsen-Karyadi, Janet L. Stanford
Publikováno v:
The Prostate. 67:410-415
BACKGROUND Prostate cancer is a genetically heterogeneous disease. Using the occurrence of other cancers in hereditary prostate cancer (HPC) families is a promising strategy for developing genetically homogeneous data sets that can enhance the abilit
Autor:
Daniel J, Schaid, Shannon K, McDonnell, Katherine E, Zarfas, Julie M, Cunningham, Scott, Hebbring, Stephen N, Thibodeau, Rosalind A, Eeles, Douglas F, Easton, William D, Foulkes, Jacques, Simard, Graham G, Giles, John L, Hopper, Lovise, Mahle, Pal, Moller, Michael, Badzioch, D Timothy, Bishop, Chris, Evans, Steve, Edwards, Julia, Meitz, Sarah, Bullock, Questa, Hope, Michelle, Guy, Chih-lin, Hsieh, Jerry, Halpern, Raymond R, Balise, Ingrid, Oakley-Girvan, Alice S, Whittemore, Jianfeng, Xu, Latchezar, Dimitrov, Bao-Li, Chang, Tamara S, Adams, Aubrey R, Turner, Deborah A, Meyers, Danielle M, Friedrichsen, Kerry, Deutsch, Suzanne, Kolb, Marta, Janer, Leroy, Hood, Elaine A, Ostrander, Janet L, Stanford, Charles M, Ewing, Marta, Gielzak, Sarah D, Isaacs, Patrick C, Walsh, Kathleen E, Wiley, William B, Isaacs, Ethan M, Lange, Lindsey A, Ho, Jennifer L, Beebe-Dimmer, David P, Wood, Kathleen A, Cooney, Daniela, Seminara, Tarja, Ikonen, Agnes, Baffoe-Bonnie, Henna, Fredriksson, Mika P, Matikainen, Teuvo L J, Tammela, Joan, Bailey-Wilson, Johanna, Schleutker, Christiane, Maier, Kathleen, Herkommer, Josef J, Hoegel, Walther, Vogel, Thomas, Paiss, Fredrik, Wiklund, Monica, Emanuelsson, Elisabeth, Stenman, Björn-Anders, Jonsson, Henrik, Grönberg, Nicola J, Camp, James, Farnham, Lisa A, Cannon-Albright, William J, Catalona, Brian K, Suarez, Kimberly A, Roehl
Publikováno v:
Human Genetics. 120:471-485
While it is widely appreciated that prostate cancers vary substantially in their propensity to progress to a life-threatening stage, the molecular events responsible for this progression have not been identified. Understanding these molecular mechani
Autor:
Lori Iwasaki, Danielle M. Friedrichsen, Ruth Etzioni, Leah P. Sabacan, Janet L. Stanford, Elaine A. Ostrander, Jainfen Shu, Mariela C. Humphrey, Sarah Hawley
Publikováno v:
The Prostate. 65:44-51
BACKGROUND Insulin-like growth factor-I (IGF-I) is a potent mitogen for both normal and malignant prostate epithelial cells. The majority of circulating IGF-I is bound in a complex with IGF binding protein-3 (IGFBP-3), which in turn limits IGF-I bioa
Autor:
Jianfeng Xu, Amanda Katz, Scott L. Friedman, Analisa DiFeo, Daniel J. Schaid, Kathleen E. Wiley, S. Lilly Zheng, Mark A. Rubin, William B. Isaacs, Goutham Narla, Arul M. Chinnaiyan, Scott J. Hebbring, Jennifer Hirshfeld, Janet L. Stanford, Patrick C. Walsh, Akira Komiya, Danielle M. Friedrichsen, Helen L. Reeves, Eldad Hod, John A. Martignetti, Elaine A. Ostrander, Shannon K. McDonnell, Stephen N. Thibodeau, Bao Li Chang, Sarah D. Isaacs, Steven J. Jacobsen
Publikováno v:
Cancer Research. 65:1213-1222
Prostate cancer is a leading and increasingly prevalent cause of cancer death in men. Whereas family history of disease is one of the strongest prostate cancer risk factors and suggests a hereditary component, the predisposing genetic factors remain
Autor:
Mette A. Peters, Mahesh B. Keitheri Cheteri, Lori Iwasaki, Ziding Feng, Danielle M. Friedrichsen, Janet L. Stanford, Mariela C. Langlois, Elaine A. Ostrander
Publikováno v:
The Prostate. 59:409-418
BACKGROUND Vitamin D is a steroid hormone that is thought to play a role in the etiology and progression of prostate cancer. Hormone activity requires binding to the vitamin D receptor (VDR), which contains several genetic polymorphisms that have bee
Autor:
Marta Janer, Suzanne Kolb, Elizabeth M. Gillanders, Gail P. Jarvik, Sarah D. Isaacs, Elaine A. Ostrander, William B. Isaacs, Janet L. Stanford, Michael D. Badzioch, Bao Li Chang, Katherine E. Wiley, Leroy Hood, Jeffrey M. Trent, S. Lilly Zheng, Patrick C. Walsh, Jianfeng Xu, Kerry Deutsch, Danielle M. Friedrichsen
Publikováno v:
Proceedings of the National Academy of Sciences. 101:1939-1944
Results from over a dozen prostate cancer susceptibility genome-wide scans, encompassing some 1,500 hereditary prostate cancer families, indicate that prostate cancer is an extremely heterogeneous disease with multiple loci contributing to overall su
Autor:
Russ Welti, Kerry Deutsch, Leroy Hood, Marta Janer, Elaine A. Ostrander, Hawkins B. DeFrance, Gail P. Jarvik, Lori Iwasaki, Mette A. Peters, Ellen L. Goode, Sarah Li, Michael D. Badzioch, Danielle M. Friedrichsen, Janet L. Stanford, Suzanne Kolb
Publikováno v:
The Prostate. 57:309-319
Hereditary prostate cancer (HPC) is a genetically heterogeneous disease, complicating efforts to map and clone susceptibility loci. We have used stratification of a large dataset of 254 HPC families in an effort to improve power to detect HPC loci an
Autor:
Danielle M. Friedrichsen, Janet R. Daling, Mariela C. Humphrey, Brian L. Strom, Nicola M. Suter, Jill A. McDonald, David R. Doody, Robert Spirtas, Polly A. Marchbanks, Ralph J. Coates, Ronald T. Burkman, Linda K. Weiss, Sandra A. Norman, Elaine A. Ostrander, Li Hsu, Jennifer Madeoy, Kathleen E. Malone, Dennis Deapen, Suzanne G. Folger, Michael S. Simon, Giske Ursin, Leslie Bernstein
Publikováno v:
Cancer research. 66(16)
Although well studied in families at high-risk, the roles of mutations in the BRCA1 and BRCA2 genes are poorly understood in breast cancers in the general population, particularly in Black women and in age groups outside of the very young. We examine
Autor:
Erin E. Carlson, Marta Janer, Daniel J. Schaid, Janet L. Stanford, Danielle M. Friedrichsen, Suzanne Kolb, Lee Hood, Shannon K. McDonnell, Kerry Deutsch, Elaine A. Ostrander
Publikováno v:
The Prostate. 66(3)
BACKGROUND Prostate cancer is a heterogeneous disease, both genetically and phenotypically. Linkage studies attempting to map genes for hereditary prostate cancer (HPC) have proved challenging, and one potential problem contributing to this challenge