Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Danielle M Maatouk"'
Autor:
S Alexandra Garcia-Moreno, Yi-Tzu Lin, Christopher R Futtner, Isabella M Salamone, Blanche Capel, Danielle M Maatouk
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
XX and XY fetal gonads are initially bipotential, poised between the ovary and testis fate. Multiple lines of evidence suggest that commitment to testis fate requires the repression of genes associated with ovary fate. It was previously shown that lo
Externí odkaz:
https://doaj.org/article/db741efa9eb345a094ebfc557ed8fba1
Autor:
Danielle M Maatouk, Lindsey Mork, Ashley Hinson, Akio Kobayashi, Andrew P McMahon, Blanche Capel
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47238 (2012)
The fetal gonad is composed of a mixture of somatic cell lineages and germ cells. The fate of the gonad, male or female, is determined by a population of somatic cells that differentiate into Sertoli or granulosa cells and direct testis or ovary deve
Externí odkaz:
https://doaj.org/article/9ebd533582894885bdec57d64415160c
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37826 (2012)
Outgrowth and patterning of the vertebrate limb requires a functional apical ectodermal ridge (AER). The AER is a thickening of ectodermal tissue located at the distal end of the limb bud. Loss of this structure, either through genetic or physical ma
Externí odkaz:
https://doaj.org/article/80b81d2666d1464da046c4f96126fb73
Autor:
Samantha A Jameson, Anirudh Natarajan, Jonah Cool, Tony DeFalco, Danielle M Maatouk, Lindsey Mork, Steven C Munger, Blanche Capel
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002575 (2012)
The divergence of distinct cell populations from multipotent progenitors is poorly understood, particularly in vivo. The gonad is an ideal place to study this process, because it originates as a bipotential primordium where multiple distinct lineages
Externí odkaz:
https://doaj.org/article/2668088155294d26b5021e2ab65592e3
Autor:
Joan S. Jorgensen, Megan L. Koth, Christopher R. Futtner, Anbarasi Kothandapani, Humphrey H.-C. Yao, Annie Novak, S. Alexandra Garcia-Moreno, Barbara Nicol, Kirsten A. Holthusen, Keer Jiang, Makoto Mark Taketo, Danielle M. Maatouk
Publikováno v:
Development.
Members of the Iroquois B (IrxB) homeodomain cluster genes, specifically Irx3 and Irx5, are critical for heart, limb, and bone development. Recently, we reported their importance for oocyte and follicle survival within the developing ovary. Irx3 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c30c8e20d08763594fe42d9c46721a3a
https://doi.org/10.1242/dev.183814
https://doi.org/10.1242/dev.183814
Autor:
Megan L, Koth, S Alexandra, Garcia-Moreno, Annie, Novak, Kirsten A, Holthusen, Anbarasi, Kothandapani, Keer, Jiang, Makoto Mark, Taketo, Barbara, Nicol, Humphrey H-C, Yao, Christopher R, Futtner, Danielle M, Maatouk, Joan S, Jorgensen
Publikováno v:
Development
Members of the Iroquois B (IrxB) homeodomain cluster genes, specifically Irx3 and Irx5, are crucial for heart, limb and bone development. Recently, we reported their importance for oocyte and follicle survival within the developing ovary. Irx3 and Ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5dbf81484daade25c252a17103f6de2
https://pubmed.ncbi.nlm.nih.gov/32108023
https://pubmed.ncbi.nlm.nih.gov/32108023
Autor:
Isabella M. Salamone, Danielle M. Maatouk, Christopher R. Futtner, Blanche Capel, Yi-Tzu Lin, S. Alexandra Garcia-Moreno
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
XX and XY fetal gonads are initially bipotential, poised between the ovary and testis fate. Multiple lines of evidence suggest that commitment to testis fate requires the repression of genes associated with ovary fate. It was previously shown that lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d06a974a7cadcd15fb7b45268edbc1
http://europepmc.org/articles/PMC6548405
http://europepmc.org/articles/PMC6548405
Autor:
Robin Lovell-Badge, Christopher R. Futtner, Nitzan Gonen, Isabella M. Salamone, S. Alexandra Garcia-Moreno, Danielle M. Maatouk
Cis-regulatory elements are critical for the precise spatiotemporal regulation of genes during development. However, identifying functional regulatory sites that drive cell differentiation in vivo has been complicated by the high numbers of cells req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb272f7b93650f100fccf0572b8384e
https://europepmc.org/articles/PMC6368449/
https://europepmc.org/articles/PMC6368449/
Autor:
Danielle M. Maatouk, Francis Poulat, Ryohei Sekido, S. Alexandra Garcia-Moreno, Chris R. Futtner, Nitzan Gonen, Sophie Wood, Isabella M. Salamone, Shiela C. Samson, Robin Lovell-Badge
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Sox9 regulation during sex determination Sex determination is regulated by the Sox9 gene. During testis differentiation, this gene is directly targeted by the product of the Y chromosome–encoded gene Sry . The regulatory region of Sox9 is complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa27d26c5145ad64edd4d5543e1df11
https://hal.archives-ouvertes.fr/hal-01974918
https://hal.archives-ouvertes.fr/hal-01974918
Autor:
Uwe Ohler, Gregory E. Crawford, Anirudh Natarajan, Yoichiro Shibata, Danielle M. Maatouk, Lingyun Song, Blanche Capel
A current goal of molecular biology is to identify transcriptional networks that regulate cell differentiation. However, identifying functional gene regulatory elements has been challenging in the context of developing tissues where material is limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2922b0469a89e6fcc8f534ec310b7c6c
http://edoc.mdc-berlin.de/16259/15/16259table-S3.xlsx
http://edoc.mdc-berlin.de/16259/15/16259table-S3.xlsx