Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Danielle M, Weiner"'
Autor:
R. M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sam
Externí odkaz:
https://doaj.org/article/78179b9a20084b6790bf89a43f40ffbf
Autor:
Maral Budak, Laura E. Via, Danielle M. Weiner, Clifton E. Barry III, Pariksheet Nanda, Gabrielle Michael, Khisimuzi Mdluli, Denise Kirschner
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 4, Pp 673-685 (2024)
Abstract Tuberculosis (TB) is a life‐threatening infectious disease. The standard treatment is up to 90% effective; however, it requires the administration of four antibiotics (isoniazid, rifampicin, pyrazinamide, and ethambutol [HRZE]) over long t
Externí odkaz:
https://doaj.org/article/ed57ab311edd4ce7b47a12de44090263
Autor:
Tiago Beites, Kathryn O’Brien, Divya Tiwari, Curtis A. Engelhart, Shaun Walters, Jenna Andrews, Hee-Jeong Yang, Michelle L. Sutphen, Danielle M. Weiner, Emmanuel K. Dayao, Matthew Zimmerman, Brendan Prideaux, Prashant V. Desai, Thierry Masquelin, Laura E. Via, Véronique Dartois, Helena I. Boshoff, Clifton E. Barry, Sabine Ehrt, Dirk Schnappinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
New tuberculosis therapies, targeting respiratory chain components of Mycobacterium tuberculosis, are under development. Here the authors show that, contrary to common belief, some of these components are not essential for pathogen viability and/or v
Externí odkaz:
https://doaj.org/article/b2df601988674fd2942c5f4b81e2ac98
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Tuberculosis (TB) remains a global health problem despite almost universal efforts to provide patients with highly effective chemotherapy, in part, because many infected individuals are not diagnosed and treated, others do not complete treatment, and
Externí odkaz:
https://doaj.org/article/3835337ebd0a4d499d384a6823beb773
Autor:
R.M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sampling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a42fa0baad62a328a1b992d88f506f
https://doi.org/10.1101/2023.04.03.535218
https://doi.org/10.1101/2023.04.03.535218
Autor:
Timm O. Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. M. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson, Rolf Müller
Publikováno v:
Journal of the American Chemical Society.
Resistance of bacterial pathogens against antibiotics is declared by WHO as a major global health threat. As novel antibacterial agents are urgently needed, we re-assessed the broad-spectrum myxobacterial antibiotic myxovalargin and found it to be ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f61df24b5a4b0bbef748e3d2b650186
https://pubmed.ncbi.nlm.nih.gov/36603206
https://pubmed.ncbi.nlm.nih.gov/36603206
Autor:
Timm O. Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson, Rolf Müller
Resistance of bacterial pathogens against antibiotics is declared by WHO as a major global health threat. As novel antibacterial agents are urgently needed, we re-assessed the broad-spectrum myxobacterial antibiotic myxovalargin and found it to be ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f6c283c2b8195cb0e7617a3d4e5c55
https://doi.org/10.26434/chemrxiv-2022-vr3hn
https://doi.org/10.26434/chemrxiv-2022-vr3hn
Autor:
Firat Kaya, Jacqueline P. Ernest, Katherine LoMauro, Martin Gengenbacher, Abdeldjalil Madani, Wassihun Wedajo Aragaw, Matthew D. Zimmerman, Jansy P. Sarathy, Nadine Alvarez, Isaac Daudelin, Han Wang, Faye Lanni, Danielle M. Weiner, Laura E. Via, Clifton E. Barry, Kenneth N. Olivier, Thomas Dick, Brendan K. Podell, Radojka M. Savic, Véronique Dartois
Publikováno v:
Antimicrob Agents Chemother
Antimicrobial agents and chemotherapy, vol 66, iss 3
Antimicrobial agents and chemotherapy, vol 66, iss 3
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a potentially fatal infectious disease requiring long treatment duration with multiple antibiotics and against which there is no reliable cure. Among the factors that have hampered the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73437e3bfdd6dc8ae59d4155e1b4de2e
https://doi.org/10.1128/aac.02212-21
https://doi.org/10.1128/aac.02212-21
Autor:
Shunsuke Sakai, Nickiana E. Lora, Keith D. Kauffman, Danielle E. Dorosky, Sangmi Oh, Sivaranjani Namasivayam, Felipe Gomez, Joel D. Fleegle, Janard L. Bleach, Ashley L. Butler, Emmuanual K. Dayao, Michaela K. Piazza, Katelyn M. Repoli, Becky Y. Slone, Michelle K. Sutphin, Alexandra M. Vatthauer, April M. Walker, Danielle M. Weiner, Michael J. Woodcock, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Alan Sher, Gordon J. Freeman, Laura E. Via, Clifton E. Barry III, Daniel L. Barber
Publikováno v:
Mucosal Immunology
Targeting MAIT cells holds promise for the treatment of different diseases and infections. We previously showed that treatment of Mycobacterium tuberculosis infected mice with 5-OP-RU, a major antigen for MAIT cells, expands MAIT cells and enhances b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c147059ba22a9d9323f23fd36684555d
https://pubmed.ncbi.nlm.nih.gov/34158594
https://pubmed.ncbi.nlm.nih.gov/34158594
Autor:
Temeri Wilder-Kofie, Daniel L. Barber, Laura E. Via, M Sutphin, Juraj Kabat, Shunsuke Sakai, Keith D. Kauffman, Clifton E. Barry, Danielle M. Weiner, Olena Kamenyeva, Ian N. Moore, Daniel Schimel, Michelle A. Sallin, Rashida Moore
Publikováno v:
Mucosal immunology
Protection against Mycobacterium tuberculosis (Mtb) infection requires CD4 T cells to migrate into the lung and interact with infected macrophages. In mice, less-differentiated CXCR3+ CD4 T cells migrate into the lung and suppress growth of Mtb, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a7754b0bb230ead13629e2cc444628
https://doi.org/10.1038/mi.2017.60
https://doi.org/10.1038/mi.2017.60