Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Danielle J. Clark"'
Autor:
Danielle J Clark, Laura E McMillan, Sin Lih Tan, Gaia Bellomo, Clementine Massoue, Harry Thompson, Lidiya Mykhaylechko, Dominic Alibhai, Xiongtao Ruan, Kentner L Singleton, Minna Du, Alan Hedges, Pamela L Schwartzberg, Paul Verkade, Robert F Murphy, Christoph Wülfing
Publikováno v:
eLife, Vol 8 (2019)
Supramolecular signaling assemblies are of interest for their unique signaling properties. A µm scale signaling assembly, the central supramolecular signaling cluster (cSMAC), forms at the center of the interface of T cells activated by antigen-pres
Externí odkaz:
https://doaj.org/article/6c4f2dbdb6a24ac88d4cbc5f40b47ea3
Autor:
Graham J Britton, Rachel Ambler, Danielle J Clark, Elaine V Hill, Helen M Tunbridge, Kerrie E McNally, Bronwen R Burton, Philomena Butterweck, Catherine Sabatos-Peyton, Lea A Hampton-O’Neil, Paul Verkade, Christoph Wülfing, David Cameron Wraith
Publikováno v:
eLife, Vol 6 (2017)
Notch is a critical regulator of T cell differentiation and is activated through proteolytic cleavage in response to ligand engagement. Using murine myelin-reactive CD4 T cells, we demonstrate that proximal T cell signaling modulates Notch activation
Externí odkaz:
https://doaj.org/article/75afcfe3d41645f7a11ec23c03da7a47
Autor:
Kole T Roybal, Emily M Mace, Danielle J Clark, Alan D Leard, Andrew Herman, Paul Verkade, Jordan S Orange, Christoph Wülfing
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133231 (2015)
Dynamic subcellular distributions of signaling system components are critical regulators of cellular signal transduction through their control of molecular interactions. Understanding how signaling activity depends on such distributions and the cellu
Externí odkaz:
https://doaj.org/article/cca45b538abd46cf9c80276683254736
Autor:
Xiongtao Ruan, Sin Lih Tan, Danielle J Clark, Clementine Massoue, Harry Thompson, Christoph Wülfing, Pamela L. Schwartzberg, A. J. Hedges, Paul Verkade, Minna Du, Kentner L. Singleton, Robert F. Murphy, Gaia Bellomo, Laura E. McMillan, Lidiya Mykhaylechko, Dominic Alibhai
Publikováno v:
Clark, D J, McMillan, L E, Tan, S L, Bellomo, G, Massoue, C, Thompson, H, Mykhaylechko, L, Alibhai, D, Ruan, X, Singleton, K L, Du, M, Hedges, A, Schwartzberg, P L, Verkade, P, Murphy, R F & Wuellfing, C 2019, ' Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion ', eLife, vol. 8, e45789 . https://doi.org/10.7554/eLife.45789
eLife, Vol 8 (2019)
Clark, D J, McMillan, L E, Tan, S L, Bellomo, G, Thompson, H F, Alibhai, D R, Hedges, A J, Verkade, P & Wuelfing, C 2019, ' Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion ', eLife . https://doi.org/10.7554/eLife.45789
eLife
eLife, Vol 8 (2019)
Clark, D J, McMillan, L E, Tan, S L, Bellomo, G, Thompson, H F, Alibhai, D R, Hedges, A J, Verkade, P & Wuelfing, C 2019, ' Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion ', eLife . https://doi.org/10.7554/eLife.45789
eLife
Supramolecular signaling assemblies are of interest for their unique signaling properties. A µm scale signaling assembly, the central supramolecular signaling cluster (cSMAC), forms at the center of the interface of T cells activated by antigen-pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4774c6b48f369885de15c659882737ae
https://hdl.handle.net/1983/fcd0794f-3d1a-414e-bfae-6181ba720761
https://hdl.handle.net/1983/fcd0794f-3d1a-414e-bfae-6181ba720761
Autor:
Danielle J Clark, Laura E McMillan, Sin Lih Tan, Gaia Bellomo, Clementine Massoue, Harry Thompson, Lidiya Mykhaylechko, Dominic Alibhai, Xiongtao Ruan, Kentner L Singleton, Minna Du, Alan Hedges, Pamela L Schwartzberg, Paul Verkade, Robert F Murphy, Christoph Wülfing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d27589d029d6f56b4107d6c36dd384
https://doi.org/10.7554/elife.45789.sa2
https://doi.org/10.7554/elife.45789.sa2
Autor:
Sin Lih Tan, Danielle J Clark, Harry Thompson, Lidiya Mykhaylechko, Laura E. McMillan, A. J. Hedges, Xiongtao Ruan, Minna Du, Paul Verkade, Robert F. Murphy, Kentner L. Singleton, Pamela L. Schwartzberg, Dominic Alibhai, Christoph Wülfing, Gaia Bellomo, Clementine Massoue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a9afccd52255e90b118b293a2ed56c1
https://doi.org/10.7554/elife.45789.044
https://doi.org/10.7554/elife.45789.044
Autor:
Danielle J Clark, Padma-Sheela Jayaraman, Ka Ying Lee, Philip Kitchen, Sebastian Oltean, Anyaporn Sawasdichai, Nikki Lau, Jomnarong Lertsuwan, Simon C. Afford, Kevin Gaston, Jutamaad Satayavivad
Publikováno v:
Cancer research. 80(4)
Aberrant Notch and Wnt signaling are known drivers of cholangiocarcinoma (CCA), but the underlying factors that initiate and maintain these pathways are not known. Here, we show that the proline-rich homeodomain protein/hematopoietically expressed ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26fdf8fc46ee3ed9c9ea806c53127ec
https://pubmed.ncbi.nlm.nih.gov/31843982
https://pubmed.ncbi.nlm.nih.gov/31843982
Autor:
Danielle J. Clark, Laura E. McMillan, Sin Lih Tan, Gaia Bellomo, Clémentine Massoué, Harry Thompson, Lidiya Mykhaylechko, Dominic Alibhai, Xiongtao Ruan, Kentner L. Singleton, Minna Du, Alan J. Hedges, Pamela L. Schwartzberg, Paul Verkade, Robert F. Murphy, Christoph Wülfing
Supramolecular signaling assemblies are of interest for their unique signaling properties. A µm scale signaling assembly, the central supramolecular signaling cluster (cSMAC), forms at the center of the interface of T cells activated by antigen pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90665445436c6c6d7e9912eabb5d70fa
Autor:
Lea A Hampton-O’Neil, Elaine V. Hill, Danielle J Clark, Kerrie E. McNally, Catherine A Sabatos-Peyton, Philomena Butterweck, Christoph Wülfing, Rachel Ambler, Graham J. Britton, Paul Verkade, Helen M Tunbridge, David C. Wraith, Bronwen R Burton
Publikováno v:
eLife
Britton, G, Ambler, R C J, Clark, D, Hill, E, Tunbridge, H, McNally, K, Burton, B, Butterweck, P, Sabatos-Peyton, C, Hampton-O'Neil, L, Verkade, P, Wuelfing, C & Wraith, D 2017, ' PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton ', eLife, vol. 6, e20003 . https://doi.org/10.7554/eLife.20003
eLife, Vol 6 (2017)
Britton, G, Ambler, R C J, Clark, D, Hill, E, Tunbridge, H, McNally, K, Burton, B, Butterweck, P, Sabatos-Peyton, C, Hampton-O'Neil, L, Verkade, P, Wuelfing, C & Wraith, D 2017, ' PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton ', eLife, vol. 6, e20003 . https://doi.org/10.7554/eLife.20003
eLife, Vol 6 (2017)
Notch is a critical regulator of T cell differentiation and is activated through proteolytic cleavage in response to ligand engagement. Using murine myelin-reactive CD4 T cells, we demonstrate that proximal T cell signaling modulates Notch activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41da55c70246aa5db4146ad1dcf029b1
http://europepmc.org/articles/PMC5310840
http://europepmc.org/articles/PMC5310840
Autor:
Padma-Sheela Jayaraman, Kevin Gaston, Jomnarong Lertsuwan, Ka Ying Lee, Jutamaad Satayavivad, Danielle J Clark, Philip Kitchen, Anyaporn Sawasdichai, S.A. Simon Afford, Sebastian Oltean
Publikováno v:
ESMO Open. 3:A67-A68
Introduction Proline-Rich Homeodomain protein/Haematopoietically Expressed Homeobox (PRH/HHEX) is a transcription factor that regulates cell proliferation, migration, and differentiation in multiple tissues. PRH is essential for embryonic development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09b5f1847be909bf51c1d4647d9c8355
https://doi.org/10.1136/esmoopen-2018-eacr25.161
https://doi.org/10.1136/esmoopen-2018-eacr25.161