Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Danielle J Smith"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42298 (2012)
Mitochondrially mediated apoptosis is characterized by redistribution of proteins from mitochondria to cytoplasm following permeabilization of the outer mitochondrial membrane. We applied flow cytometry to quantify simultaneously the redistribution o
Externí odkaz:
https://doaj.org/article/6f78b2395e0b4e8c927ba4955ce0b19e
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24473 (2011)
Increased expression of Hsp72 accompanies differentiation of human neuroblastoma SH-SY5Y cells to neuron-like cells. By modulating cellular levels of Hsp72, we demonstrate here its anti-apoptotic activity both in undifferentiated and neuron-like cell
Externí odkaz:
https://doaj.org/article/22e7fbaff323422791ee1815ba7cf9bc
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000516 (2009)
Programmed necrosis is a mechanism of cell death that has been described for neuronal excitotoxicity and ischemia/reperfusion injury, but has not been extensively studied in the context of exposure to bacterial exotoxins. The alpha-toxin of Clostridi
Externí odkaz:
https://doaj.org/article/fabebe6493934b419f2b90473bf4f3ab
Autor:
Kamilla JA. Bigos, Conrado G. Quiles, Sapna Lunj, Danielle J. Smith, Mechthild Krause, Esther GC. Troost, Catharine M. West, Peter Hoskin, Ananya Choudhury
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Hypoxia is a common feature of solid tumours affecting their biology and response to therapy. One of the main transcription factors activated by hypoxia is hypoxia-inducible factor (HIF), which regulates the expression of genes involved in various as
Externí odkaz:
https://doaj.org/article/70746ca5d8dc42c8b14bd3e89d563db3
Autor:
Katie L. Davies, Emily J. Camm, Danielle J. Smith, Jack Miles, Alison J. Forhead, Andrew J. Murray, Abigail L. Fowden
Publikováno v:
Journal of developmental origins of health and disease.
Prenatal glucocorticoid overexposure causes adult metabolic dysfunction in several species but its effects on adult mitochondrial function remain largely unknown. Using respirometry, this study examined mitochondrial substrate metabolism of fetal and
Publikováno v:
Canadian Journal of Counselling and Psychotherapy. 55
Given that an increasing number of newcomer youth enter high schools in Canada each year, educational settings are faced with the challenge of creating programming and policies that promote a positive integration process. As part of a larger study th
Autor:
Peter Wooding, Abigail L. Fowden, Akshay Easwaran, Katie L. Davies, Tatiana El-Bacha, Danielle J. Smith, Emily J. Camm, Andrew J. Murray, Alison J. Forhead, Max E. Stewart
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(5)
Thyroid hormones regulate adult metabolism partly through actions on mitochondrial oxidative phosphorylation (OXPHOS). They also affect neurological development of the brain, but their role in cerebral OXPHOS before birth remains largely unknown, des
Autor:
Katie L. Davies, Danielle J. Smith, Tatiana El-Bacha, Peter F. P. Wooding, Alison J. Forhead, Andrew J. Murray, Abigail L. Fowden, Emily J. Camm
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 768 (2022)
In adults, glucocorticoids are stress hormones that act, partly, through actions on mitochondrial oxidative phosphorylation (OXPHOS) to increase energy availability. Before birth, glucocorticoids are primarily maturational signals that prepare the fe
Externí odkaz:
https://doaj.org/article/a50548faa67442c3a0527046f26665eb