Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency

Autor: Crystal Sang, Sasha A. Philbert, Danielle Hartland, Richard. D Unwin, Andrew W. Dowsey, Jingshu Xu, Garth J. S. Cooper

Publikováno v: University of Manchester-PURE
Sang, C, Philbert, S, Hartland, D, Unwin, R, Dowsey, A, Xu, J & Cooper, G JS 2022, ' Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency ', Frontiers in aging neuroscience, vol. 14, no. 893159, 893159, pp. 893159 . https://doi.org/10.3389/fnagi.2022.893159
Sang, C, Philbert, S A, Hartland, D, Unwin, R D, Dowsey, A W, Xu, J & Cooper, G J S 2022, ' Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer's Disease Consistent With Cerebral Pantothenate Deficiency ', Frontiers in Aging Neuroscience, vol. 14, 893159 . https://doi.org/10.3389/fnagi.2022.893159

Sporadic Alzheimer’s disease (sAD) is the commonest cause of age-related neurodegeneration and dementia globally, and a leading cause of premature disability and death. To date, the quest for a disease-modifying therapy for sAD has failed, probably

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https://www.research.manchester.ac.uk/portal/en/publications/coenzyme-adependent-tricarboxylic-acid-cycle-enzymes-are-decreased-in-alzheimers-disease-consistent-with-cerebral-pantothenate-deficiency(6cddd9bf-44da-40d1-8fa6-2b00c578ceff).html