Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Danielle Harbour"'
Autor:
Sylvain G. Bourgoin, François Chouinard, Danielle Harbour, Delphine Faugaret, Mohammed-Amine El Azreq
Publikováno v:
Biochemical Pharmacology. 81:144-156
Although phosphatidic acid (PA) regulates a wide variety of physiological processes, its targets remain poorly characterized in human neutrophils. By co-sedimentation with PA-containing vesicles we identified several PA-binding proteins including ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e58de380fa8ac1d1dc815b59b7d5d46
https://doi.org/10.1016/j.bcp.2010.09.014
https://doi.org/10.1016/j.bcp.2010.09.014
Autor:
François Chouinard, Danielle Harbour, Christophe Pivot-Pajot, Sylvain G. Bourgoin, Mohammed Amine El Azreq
Publikováno v:
Immunobiology. 215:38-52
Exocytosis of neutrophil granules is a major event that converts circulating neutrophils into fully activated cells capable of chemotaxis, phagocytosis and destruction of pathogens. The PLB-985 cell line is a suitable neutrophilic cellular model whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c3d2852329f3f8d1296c1d4e90b856
https://doi.org/10.1016/j.imbio.2009.01.007
https://doi.org/10.1016/j.imbio.2009.01.007
Publikováno v:
Biochemical Pharmacology. 74:730-741
Prostaglandin E2 (PGE2), an eicosanoid that modulates inflammation, inhibits several chemoattractant-elicited functions in neutrophils such as chemotaxis, production of superoxide anions, adhesion, secretion of cytotoxic enzymes and synthesis of leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1fb524fa52c488910c44e522d19e8d
https://doi.org/10.1016/j.bcp.2007.06.013
https://doi.org/10.1016/j.bcp.2007.06.013
Publikováno v:
Journal of Leukocyte Biology. 79:574-585
Four types of adenosine receptors have been identified in different tissues and cell types, namely, A1, A2A, A2B, and A3 receptors. We report that A2AR but not A2BR mRNA in freshly isolated polymorphonuclear neutrophils (PMN) is maximally up-regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0834ab6dde6156a8ae61f2e7619e800d
https://doi.org/10.1189/jlb.0505249
https://doi.org/10.1189/jlb.0505249
Autor:
Andrew J. Morris, Steve N. Gagnon, Indrapal N. Singh, Martin G. Houle, Sylvain G. Bourgoin, Danielle Harbour, David N. Brindley
Publikováno v:
Journal of Leukocyte Biology. 71:718-728
Cytohesin-1 and ARNO are guanine nucleotide-exchange factors (GEFs) for ADP-ribosylation factor (Arf). Here, we show that ARNO is expressed in HL-60 cells and established that granulocytic differentiation induced with Me2SO stimulated cytohesin-1 but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae0e1b0a46b62af89c88709a3300e40
https://doi.org/10.1189/jlb.71.4.718
https://doi.org/10.1189/jlb.71.4.718
Autor:
Chantal Burelout, Paul H. Naccache, Danielle Harbour, Nathalie Thibault, Pierre Borgeat, Sylvain G. Bourgoin
Publikováno v:
Scopus-Elsevier
The aim of this study was to assess in human neutrophils theimplication of an adenosine 3′,5′-cyclic monophosphate (cAMP)-dependentpathway in the inhibitory effects of A2a receptor engagement. We foundthat Ro20-1724, a cAMP phosphodiesterase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d2b964822d91a31d58ed12885c7672
https://doi.org/10.1189/jlb.71.2.367
https://doi.org/10.1189/jlb.71.2.367
Autor:
Steve N. Gagnon, Danielle Harbour, Martin G. Houle, Sylvain G. Bourgoin, François Chouinard, Valérie Garceau, Paul H. Naccache
Publikováno v:
Journal of Immunological Methods. 249:121-136
ADP-ribosylation factors (Arf) are small GTP-binding proteins involved in vesicular transport and the activation of phospholipase D (PLD). The conversion of Arf-GDP to Arf-GTP is promoted in vivo by guanine nucleotide exchange factors such as ARNO or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf84f167c4023bfc2991873cfb944600
https://doi.org/10.1016/s0022-1759(00)00336-7
https://doi.org/10.1016/s0022-1759(00)00336-7
Publikováno v:
Biochemical Journal. 337:185-192
Protein kinase Calpha (PKCalpha) and small GTPases of the Rho and ADP-ribosylation factor (Arf) family are implicated in the regulation of phospholipase D1 (PLD1) activity. Although they are involved in fMet-Leu-Phe (fMLP)-mediated PLD activation, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395ff1f7d0959d209cf59cb7cfd326de
https://doi.org/10.1042/bj3370185
https://doi.org/10.1042/bj3370185
Publikováno v:
Journal of Biological Chemistry. 270:3172-3178
Phospholipase D (PLD) activation by guanine nucleotides requires protein cofactors in both the plasma membrane and the cytosol. HL-60 cytosol was fractionated by ammonium sulfate and gel-permeation chromatography. Two cytosolic protein fractions were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d071a394140579d0800057d72630e15
https://doi.org/10.1074/jbc.270.7.3172
https://doi.org/10.1074/jbc.270.7.3172
Autor:
Mohammed-Amine El Azreq, Danielle Harbour, Sylvain G. Bourgoin, Valérie Garceau, Christophe Pivot-Pajot
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(2)
Polymorphonuclear neutrophil (PMN) stimulation with fMLP stimulates small G proteins such as ADP-ribosylation factors (Arfs) Arf1 and Arf6, leading to phospholipase D (PLD) activation and functions such as degranulation and the oxidative burst. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f54db12ced8af153567fcaced1ee95a
https://pubmed.ncbi.nlm.nih.gov/20018626
https://pubmed.ncbi.nlm.nih.gov/20018626