The association of the triglyceride-to-HDL cholesterol ratio with insulin resistance in White European and South Asian men and women.

Autor: Samiul A Mostafa, Melanie J Davies, Danielle H Morris, Tom Yates, Balasubramanian Thiagarajan Srinivasan, David Webb, Emer Brady, Kamlesh Khunti

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50931 (2012)

INTRODUCTION:There is recent interest surrounding the use of the triglyceride-to-HDL cholesterol ratio as a surrogate marker of insulin resistance in clinical practice, as it may identify people at high risk of developing diabetes or its complication

Externí odkaz: https://doaj.org/article/d4442539f01b4937bdb06888b72a5159

Population-based estimates of the prevalence of FMR1 expansion mutations in women with early menopause and primary ovarian insufficiency

Autor: Minouk J. Schoemaker, Sarah Ennis, Anna Murray, Danielle H. Morris, Claire E. Bennett, Anthony J. Swerdlow, Alan Ashworth, Patricia A. Jacobs, Nick Orr, Michael Jones, James N. Macpherson

Publikováno v: Murray, A, Schoemaker, M J, Bennett, C E, Ennis, S, Macpherson, J N, Jones, M, Morris, D H, Orr, N, Ashworth, A, Jacobs, P A & Swerdlow, A J 2014, ' Population-based estimates of the prevalence of FMR1 expansion mutations in women with early menopause and primary ovarian insufficiency ', Genetics in medicine : official journal of the American College of Medical Genetics, vol. 16, no. 1, pp. 19-24 . https://doi.org/10.1038/gim.2013.64
Genetics in Medicine

PURPOSE: Primary ovarian insufficiency before the age of 40 years affects 1% of the female population and is characterized by permanent cessation of menstruation. Genetic causes include FMR1 expansion mutations. Previous studies have estimated mutati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1105c6e0cbce3d46306c5ea603824e7d
https://doi.org/10.1038/gim.2013.64

Diabetes and cardiovascular events in women with polycystic ovary syndrome: a 20-year retrospective cohort study

Autor: Hamidreza Mani, John Bankart, Trevor A. Howlett, Hannah Blackledge, Miles J Levy, Laura J. Gray, Kamlesh Khunti, Melanie J. Davies, Danielle H. Morris

Publikováno v: Clinical Endocrinology. 78:926-934

SummaryObjective Women with polycystic ovary syndrome (PCOS) are potentially at increased risk of cardiovascular (CV) diseases due to well-established risk factors, including insulin resistance, obesity and type 2 diabetes mellitus (T2DM). However, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d7bc8ef2945fdcf4ce6f5d24b5b4be
https://doi.org/10.1111/cen.12068

The association between body mass index and health-related quality of life: influence of ethnicity on this relationship

Autor: Navneet Aujla, C. McDonough, Alison J. Dunkley, Danielle H. Morris, Kamlesh Khunti, Melanie J. Davies

Publikováno v: Diabetes, Obesity and Metabolism. 15:342-348

Aims The association between obesity and a poorer health-related quality of life (HRQL) has previously been explored. The influence of ethnicity on this relationship has less frequently been considered. We aimed to explore the relationship between bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35ea0ab25342ea630b485f69fcc97b6
https://doi.org/10.1111/dom.12033

Familial concordance for age at natural menopause

Autor: Michael Jones, Danielle H. Morris, Anthony J. Swerdlow, Minouk J. Schoemaker, Alan Ashworth

Publikováno v: Menopause. 18:956-961

Existing estimates of the heritability of menopause age have a wide range. Furthermore, few studies have analyzed to what extent familial similarities might reflect shared environment, rather than shared genes. We therefore analyzed familial concorda

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcbceab53f2417e1aaf4d99b540ba84
https://doi.org/10.1097/gme.0b013e31820ed6d2