Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Danielle Gully"'
Autor:
Danielle Gully, Nicole Vaysse, Jean Martinez, M. Bouisson, Véronique Gigouj, Bernard Maigret, Daniel Fourmy, Jean-Alain Fehrentz, Chantal Escrieut, Sandrine Silvente-Poirot, Luis Moroder
Publikováno v:
Protein Science
Protein Science, Wiley, 1999, 11, pp.2347-2354
Scopus-Elsevier
HAL
Protein Science, Wiley, 1999, 11, pp.2347-2354
Scopus-Elsevier
HAL
The knowledge of the binding sites of G protein-coupled cholecystokinin receptors represents important insights that may serve to understand their activation processes and to design or optimize ligands. Our aim was to identify the amino acid of the c
Autor:
M. Jung, Pierre Roger, Michel Geslin, Jacques Simiand, Jean-Pierre Maffrand, Guy Griebel, Régis Steinberg, Philippe Soubrie, Danielle Gully, Bernard Scatton
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:333-345
The present study investigated the effects of the novel corticotrophin-releasing factor (CRF) 1 receptor antagonist 4-(2-chloro-4-methoxy-5-methylphenyl)- N -[(1 S )-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl- N -(2-propynyl)-1,3-thiazol
Autor:
Régis Steinberg, Jean-Pierre Maffrand, Pierre Roger, Georgette Gout, Philippe Soubrie, Evelyne Fontaine, Christine Lair, Danielle Gully, Marc Pascal, Valerie Darre, Michel Geslin, Jacques Simiand, Gérard Le Fur, Rebecca M. Pruss, Pierre-Eric Rouby, Bernard Scatton, Laurence Serva, Josette Guitard, Claudine Marcy, D. Rodier, Guy Griebel
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:322-332
4-(2-Chloro-4-methoxy-5-methylphenyl)- N -[(1 S )-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl- N -(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or
Autor:
Pascual Ferrara, Jean-Pierre Maffrand, Giulio Aureggi, Gérard Le Fur, Gianfranco Ferla, Luciano Manara, Tiziano Croci, Sylvain Mukenge, Danielle Gully, Natalio Vita, Fabio Guagnini, Pascale Chalon
Publikováno v:
British Journal of Pharmacology. 127:1922-1928
1. The newly developed non-peptide neurotensin (NT)-receptor antagonists SR 48692 and SR 142948 were used to challenge NT responses of human colonic circular smooth muscle strips in vitro. The presence of NT1 and NT2 receptor transcripts in this tiss
Autor:
Bernard Labeeuw, Maryse Canton, Didier Pélaprat, Danielle Gully, Catalina Betancur, Alain Burgos, William Rostène
Publikováno v:
European Journal of Pharmacology. 343:67-77
The present study describes the characterization of the binding properties and autoradiographic distribution of a new nonpeptide antagonist of neurotensin receptors, [3H]SR 142948A (2-[[5-(2,6-dimethoxyphenyl)-1-(4-(N-(3-dimethylaminopropyl)-N-methyl
Autor:
Martial Ruat, Christine Lair, Danielle Gully, Bruno Chatel, Jean-Pierre Maffrand, Robert H. Dodd, Sandrine Ferry
Publikováno v:
Biochemical and Biophysical Research Communications. 238:866-873
The calcium sensing receptor (CaSR), a member of the G-protein coupled receptor family, is expressed on a variety of cell types and responds to extracellular calcium. We have characterized pharmacological properties of (+/-)NPS 568, a calcimimetic, t
Autor:
B. Mark Evers, Kazuhiro Iwase, Danielle Gully, Courtney M. Townsend, Hong Jin Kim, Mark R. Hellmich, Shunichi Higashide, James C. Thompson
Publikováno v:
Cancer. 79:1787-1793
BACKGROUND Recently, a nonpeptide neurotensin (NT) receptor antagonist, SR48692, was developed that selectively antagonizes the high affinity, biologically active NT binding site. The effect of SR48692 on NT-mediated growth of a human pancreatic carc
Autor:
Valérie Prabonnaud, Liliane Lespy, Marie-Claude Laplace, Jean-Marc Herbert, Andre Bernat, Danielle Gully, Paul J. Schaeffer
Publikováno v:
European Journal of Pharmacology. 323:215-221
Human umbilical vein endothelial cells express high affinity neurotensin receptors which are coupled to phosphoinositide turnover and 45Ca2+ efflux (Schaeffer et al., 1995. J. Biol. Chem. 270, 3409-3413). In order to assess the physiological signific
Autor:
Jean-Pierre Maffrand, Luciano Manara, Gérard Le Fur, Marco Landi, Tiziano Croci, Danielle Gully
Publikováno v:
British Journal of Pharmacology. 120:1312-1318
We investigated the effect of the non-peptide neurotensin (NT) antagonist SR 48692 on renal function in rats and the involvement of nitric oxide (NO) in the diuretic action of this compound. In fed animals, SR 48692 dose-dependently (0.5 to 12.5 mg k
Autor:
Jean Martinez, Nicole Vaysse, Daniel Fourmy, Véronique Gigoux, Bernard Maigret, Daniel Allée de Barcelone Frehel, Luis Moroder, Danielle Gully, K. Kennedy, Chantal Escrieut
Publikováno v:
Journal of Biological Chemistry. 272:2920-2926
A region between residues 38 and 42 of the human cholecystokinin-A (CCK-A) receptor was shown to be involved in the binding of CCK but not in that of JMV 179 and JMV 180, two peptides closely related to CCK (Kennedy, K., Escrieut, C., Dufresne, M., C