Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Danielle Froio"'
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9f98530e31300fe125ac252f05b19
https://doi.org/10.1158/0008-5472.22417851
https://doi.org/10.1158/0008-5472.22417851
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p mimic transfection sensitized MCF7 cells to a fractionated radiation dose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b063a366ab14c4b3f8b57327f6b6dc60
https://doi.org/10.1158/0008-5472.22417857.v1
https://doi.org/10.1158/0008-5472.22417857.v1
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Comparative genomics of predicted miR-139-5p binding sites across 15 eutherian mammals (A). Correlation between endogenous miR-139-5p expression and predicted targets in 207 primary BC tumors (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1953aa9840e2b24f878461e4da86a437
https://doi.org/10.1158/0008-5472.22417854
https://doi.org/10.1158/0008-5472.22417854
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Supplementary Tables 1-6 Supp. Table 1: Clinicopathological characteristics of breast cancer patients whose tumours were profiled by miRNA expression microarrays to identify miRNAs associated with local relapse following radiotherapy. Supp. Table 2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f951d92c4452a370f5c128e23ffa4fa
https://doi.org/10.1158/0008-5472.22417845
https://doi.org/10.1158/0008-5472.22417845
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26eaaad942be250caced776fa8fee5
https://doi.org/10.1158/0008-5472.c.6509961
https://doi.org/10.1158/0008-5472.c.6509961
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
RT + miR-139-5p mimic-treated tumours had significantly decreased Ki-67-positive cells, and significantly increased phospho-H2AX- and caspase-3-positive cells compared to control mimic-treated tumours (A-C). phospho-H2AX immunostaining was confined t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa8628a42b861b37b85c2ec67b9b2a
https://doi.org/10.1158/0008-5472.22417848.v1
https://doi.org/10.1158/0008-5472.22417848.v1
Autor:
Dylan Corl, Dan Prillaman, Christopher Thellen, Simone Rodriguez, Patrick S. Mark, Cosme Furlong, Shannon Carey, Margot Meredith, Ramona Gaza, Robert Hitchner, Lenore Rasmussen, Stephanie Liffland, Michael J. Menegus, Laurie Bagley, Catherine Poirier, Robert Nodarse, Thomas Seacrist, Tyler Fuerst, Logan Valenza, Danielle Froio, Greig Martino, Jo Ann Ross-Ratto, Tianyu Cheng, Matthew P. Bowers, Peter N. Vicars, M. Damaris Smith, Nicole Allen, James Taylor, Calum R. Briggs, Dan Hoffman, Payam Razavi, Whitney Blocher, Ben Secino, Alex Zhong, Charles Gentile, George Ascione, Edward A. Clancy, Sergio Gallucci, L. Meixler, Leila N. Albers, Leon Moy, Surbhi Hablani, Matthew R. Maltese, Charles Sinkler
Publikováno v:
Smart Materials ISBN: 9783030705121
Smart Materials
Smart Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db17e7c849a75cc1eb032681727298ef
https://doi.org/10.1007/978-3-030-70514-5_1
https://doi.org/10.1007/978-3-030-70514-5_1
Autor:
Ann Barrett, Michelle Richardson, Lauren F. O' Connor, Danielle Froio, Tshinanne Ndou, Danielle J. Anderson
Publikováno v:
Journal of Food Science. 83:2183-2190
Multiyear spaceflight will require innovative strategies to preserve vitamins in foods, in order to retain astronaut health and functionality long-term. Furthermore, space foods must be low weight/volume to comply with cargo restrictions, and must re
Autor:
John Turchini, Danielle Froio, Paul Timpson, Marina Pajic, Stacey N. Walters, Amber L. Johns, Mark J. Cowley, Angela Steinmann, Thomas R. Cox, Shane T. Grey, Andrew Burgess, Claire Vennin, David K. Chang, Owen J. Sansom, Dalia Wohl, Timothy J. Molloy, Andrew V. Biankin, Angela Chou, Adnan Nagrial, Lorraine A. Chantrill, Rhys Stark, Mark Pinese, Stephen Clarke, Jaswinder S. Samra, Alison Drury, Ashleigh Parkin, Venessa T. Chin, Kendelle J. Murphy, Sean M. Grimmond, Nicola Waddell, Jennifer P. Morton, Anthony J. Gill
Publikováno v:
Gut
ObjectiveExtensive molecular heterogeneity of pancreatic ductal adenocarcinoma (PDA), few effective therapies and high mortality make this disease a prime model for advancing development of tailored therapies. The p16-cyclin D-cyclin-dependent kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f16f383a8580141705662de52823c31
https://eprints.gla.ac.uk/151422/1/151422.pdf
https://eprints.gla.ac.uk/151422/1/151422.pdf
Autor:
Ramzi H. Abbassi, Michael Kassiou, Jennifer Man, Monira Hoque, Lenka Munoz, Bryan W. Day, Danielle Froio, Terrance Grant Johns, Marina Pajic, Brett W. Stringer
Publikováno v:
Pharmacological research. 134
In the field of kinase inhibitors for applications in cancer research, tubulin is emerging as a targeted cellular protein that can significantly contribute to their activities. However, investigation of kinase inhibitors beyond the kinome is an area