Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Danielle Fletcher"'
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Unravelling the link between genes and environment across the life cycle is a challenging goal that requires model organisms with well-characterized life-cycles, ecological interactions in nature, tractability in the laboratory, a
Externí odkaz:
https://doaj.org/article/3680f9c4c774442cbd6b0b57a3f83f17
Autor:
George S. Vassiliou, João M. L. Dias, Naomi Park, Jorge Sierra, Nicla Manes, David Bloxham, German Tischler, Clare Hodkinson, Josep F. Nomdedeu, Jianxiang Chi, Bram Herman, Niccolo Bolli, Ignacio Varela, Danielle Fletcher, Ville Mustonen, Michael A. Quail, Anthony J. Bench, Vincenza Colonna, Zemin Ning, Thomas McKerrell, Bridget Manasse, Chris Tyler-Smith, Carolyn S. Grove, Theodora Foukaneli, Alan J. Warren, Brian J. P. Huntly, Roland Rad, Paul Costeas, Joanna Baxter, Hannes Ponstingl, Michael A. Scott, Thaidy Moreno
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Blood 128 (2016): E1–E9. doi:10.1182/blood-2015-11-683334
info:cnr-pdr/source/autori:McKerrell, Thomas; Moreno, Thaidy; Ponstingl, Hannes; Bolli, Niccolo; Dias, Joao M. L.; Tischler, German; Colonna, Vincenza; Manasse, Bridget; Bench, Anthony; Bloxham, David; Herman, Bram; Fletcher, Danielle; Park, Naomi; Quail, Michael A.; Manes, Nicla; Hodkinson, Clare; Baxter, Joanna; Sierra, Jorge; Foukaneli, Theodora; Warren, Alan J.; Chi, Jianxiang; Costeas, Paul; Rad, Roland; Huntly, Brian; Grove, Carolyn; Ning, Zemin; Tyler-Smith, Chris; Varela, Ignacio; Scott, Mike; Nomdedeu, Josep; Mustonen, Ville; Vassiliou, George S./titolo:Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies/doi:10.1182%2Fblood-2015-11-683334/rivista:Blood/anno:2016/pagina_da:E1/pagina_a:E9/intervallo_pagine:E1–E9/volume:128
BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Blood
instname
Blood 128 (2016): E1–E9. doi:10.1182/blood-2015-11-683334
info:cnr-pdr/source/autori:McKerrell, Thomas; Moreno, Thaidy; Ponstingl, Hannes; Bolli, Niccolo; Dias, Joao M. L.; Tischler, German; Colonna, Vincenza; Manasse, Bridget; Bench, Anthony; Bloxham, David; Herman, Bram; Fletcher, Danielle; Park, Naomi; Quail, Michael A.; Manes, Nicla; Hodkinson, Clare; Baxter, Joanna; Sierra, Jorge; Foukaneli, Theodora; Warren, Alan J.; Chi, Jianxiang; Costeas, Paul; Rad, Roland; Huntly, Brian; Grove, Carolyn; Ning, Zemin; Tyler-Smith, Chris; Varela, Ignacio; Scott, Mike; Nomdedeu, Josep; Mustonen, Ville; Vassiliou, George S./titolo:Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies/doi:10.1182%2Fblood-2015-11-683334/rivista:Blood/anno:2016/pagina_da:E1/pagina_a:E9/intervallo_pagine:E1–E9/volume:128
BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Blood
et al.
The diagnosis of hematologic malignancies relies on multidisciplinary workflows involving morphology, flow cytometry, cytogenetic, and molecular genetic analyses. Advances in cancer genomics have identified numerous recurrent mutations wi
The diagnosis of hematologic malignancies relies on multidisciplinary workflows involving morphology, flow cytometry, cytogenetic, and molecular genetic analyses. Advances in cancer genomics have identified numerous recurrent mutations wi
Autor:
Probir Chakravarty, Paul Kirkham, Irfan Rahman, Gillian Spooner, David Adenuga, Ian L. Megson, Isaac K. Sundar, Danielle Fletcher, Saravanan Rajendrasozhan, Paul A. Whittaker, Koremu Meja, John A. Marwick, Saibal K. Biswas
Publikováno v:
Meja, K K, Rajendrasozhan, S, Adenuga, D, Biswas, S K, Sundar, I K, Spooner, G, Marwick, J A, Chakravarty, P, Fletcher, D, Whittaker, P, Megson, I L, Kirkham, P A & Rahman, I 2008, ' Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2 ', American Journal of Respiratory Cell and Molecular Biology, vol. 39, no. 3, pp. 312-23 . https://doi.org/10.1165/rcmb.2008-0012OC
Oxidative stress as a result of cigarette smoking is an important etiologic factor in the pathogenesis of chronic obstructive pulmonary disease (COPD), a chronic steroid-insensitive inflammatory disease of the airways. Histone deacetylase-2 (HDAC2),
Autor:
Peter J. Scambler, Sinthuja Sivagnanasundaram, Danielle Fletcher, Mike Hubank, David Skuse, Elizabeth Illingworth
Publikováno v:
Brain Research. 1139:48-59
Genes and a 3-Mb deletion mapping to human chromosome 22q11.2 have been implicated in 22q11.2 deletion syndrome (22q11.2DS) and schizophrenia. The Df1 heterozygous (Df1/+) mice, a model for 22q11.2DS, display specific deficits in hippocampus-dependen
Autor:
Danielle Fletcher, Paul Moss, Christopher Fegan, Victoria J Weston, Debbie Cronin, A. Malcolm R. Taylor, Tatjana Stankovic, Colin R. Bignell, Belinda Austen, Philip J. Byrd, Azra J. Alvi, Grant S. Stewart, Mike Hubank
Publikováno v:
Blood. 103:291-300
The ATM/p53-dependent DNA damage response pathway plays an important role in the progression of lymphoid tumors. Inactivation of the ATM or TP53 gene is frequent in B-cell lymphocytic leukemia (B-CLL) and leads to aggressive disease. Although the ATM
Publikováno v:
Heart Rhythm. 8:328-330
Case summary S.S., a 38-year-old man, struck a cow while driving his vehicle. After the accident, while he was outside the vehicle inspecting the situation, he was anxious and shook his fist in frustration. He felt palpitations and associated dizzine
Autor:
Gillian Wallis, Ian M. Adcock, Kazuhiro Ito, Tewis Bouwmeester, Bernhard Kuster, Peter J. Barnes, Danielle Fletcher, John A. Marwick, Paul A. Whittaker, Koremu Meja, Probir Chakravarty, Paul Kirkham
Publikováno v:
Biochemical and biophysical research communications. 377(3)
Oxidative stress is a central factor in many chronic inflammatory diseases such as severe asthma and chronic obstructive pulmonary disease (COPD). Oxidative stress reduces the anti-inflammatory corticosteroid action and may therefore contribute to th
Autor:
Naina Patel, Danielle Fletcher, Alexander S. Hill, Bryan D. Young, Mike Hubank, Olga Yiannikouris, Tracy Chaplin, Louise Jones, Alexander Gammerman, Ian Hann, Vaskar Saha, Tony Bellotti, Nicola J. Foot, Zhiyuan Luo, Helena Kempski, Frederik W. van Delft
Publikováno v:
British journal of haematology. 130(1)
We have prospectively analysed and correlated the gene expression profiles of children presenting with acute leukaemia to the Royal London and Great Ormond Street Hospitals with morphological diagnosis, immunophenotype and karyotype. Total RNA extrac