Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Danielle E. Mor"'
Autor:
Lauren M. McIntyre, Francisco Huertas, Alison M. Morse, Rachel Kaletsky, Coleen T. Murphy, Vrinda Kalia, Gary W. Miller, Olexander Moskalenko, Ana Conesa, Danielle E. Mor
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood, limiting the
Externí odkaz:
https://doaj.org/article/7b6b9565a6ca4caa885a23452e6ff4cd
Autor:
Merry Chen, Danielle E. Mor
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7205 (2023)
Parkinson’s disease (PD) is a multifactorial disorder involving both motor and non-motor symptoms caused by the progressive death of distinct neuronal populations, including dopaminergic neurons in the substantia nigra. The deposition of aggregated
Externí odkaz:
https://doaj.org/article/35823a2d52384290a0f77a5c8f981eec
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Salman Sohrabi et al. develop an automated, high-throughput assay to study spasm-like curling behavior in C. elegans, which is related to motor control symptoms in Parkinson’s disease. They apply this screening approach to identify four candidate d
Externí odkaz:
https://doaj.org/article/74da37c3af4d4181ad273528c6947316
Autor:
Danielle E. Mor, Coleen T. Murphy
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 117-120 (2020)
Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson’s disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and the use of complex I inh
Externí odkaz:
https://doaj.org/article/1d27ec0f02154eada7f13f1344fd218f
Publikováno v:
Neurobiology of Disease, Vol 88, Iss , Pp 66-74 (2016)
α-Synuclein is a conserved, abundantly expressed protein that is partially localized in pre-synaptic terminals in the central nervous system. The precise biological function(s) and structure of α-synuclein are under investigation. Recently, the nat
Externí odkaz:
https://doaj.org/article/9a5928b5cdae4427a2bf0c48508ec6f6
Autor:
Danielle E Mor, Harry Ischiropoulos
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
In Parkinson’s disease (PD), the loss of dopamine-producing neurons in the substantia nigra (SN) leads to severe motor impairment, and pathological inclusions known as Lewy bodies contain aggregated α-synuclein protein. The relationship of α-synu
Externí odkaz:
https://doaj.org/article/63e930f224404a86b385bfa5f9a6b7fa
Autor:
Saurabh Wakade, Danielle E. Mor, Julie Vincent, Merry Chen, Alexis Ezeanii, Shobha Yerigenahally
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder characterized by progressive motor decline and the aggregation of α-synuclein protein. Growing evidence suggests that α-synuclein aggregates may spread from neurons of the dige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43a8ea3dc14291b99b0842ae04e2dfad
https://doi.org/10.1101/2021.11.11.468276
https://doi.org/10.1101/2021.11.11.468276
Autor:
Merry Chen, Julie Vincent, Alexis Ezeanii, Saurabh Wakade, Shobha Yerigenahally, Danielle E Mor
Publikováno v:
Life Science Alliance. 5:e202201366
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder characterized by progressive motor decline and the aggregation of α-synuclein protein. Growing evidence suggests that α-synuclein aggregates may spread from neurons of the dige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2331a053ec6d0660ef192f07b593fa12
https://doi.org/10.26508/lsa.202201366
https://doi.org/10.26508/lsa.202201366
Autor:
Nathaniel W Hartman, Joseph E Carpentino, Kristi LaMonica, Danielle E Mor, Janice R Naegele, Laura Grabel
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15856 (2010)
Stem cell therapies for neurodegenerative disorders require accurate delivery of the transplanted cells to the sites of damage. Numerous studies have established that fluid injections to the hippocampus can induce lesions in the dentate gyrus (DG) th
Externí odkaz:
https://doaj.org/article/f007bdb1e0154687a2ba5ebd1750e920