Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Danielle Duquette"'
Autor:
Xavier Michelet, Róisín M. Loftus, Kingston H. G. Mills, Danielle Duquette, Andrew E. Hogan, Lydia Lynch, Barbara S. Nikolajczyk, Michael B. Brenner, Lydia Dyck, Cliona O'Farrelly, Cathriona Foley, Ashley H. Vernon, David K. Finlay, William Pettee, Raymond P. Donnelly, Kevin Wei, Ali Tavakkoli, Semir Beyaz, Mathilde Raverdeau, Donal O'Shea
Publikováno v:
Nature Immunology
Up to 49% of certain types of cancer are attributed to obesity, and potential mechanisms include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells, including natural killer (NK) cells and CD8+ T cells, are important in tumor
Autor:
Nelson M. LaMarche, Ayano C. Kohlgruber, Tyler Paras, Danielle Duquette, Lydia Lynch, Alexander S. Banks, Amir I. Mina, Adam P Uldrich, Shani T. Gal-Oz, Dale I. Godfrey, Michael B. Brenner, Ali Tavakkoli, Ulrich H. von Andrian, Tal Shay, Hung N. Nguyen, Moto Shimazaki, Hui-Fern Koay
Publikováno v:
Nature Immunology
Nat Immunol
Nat Immunol
γδ T cells are situated at barrier sites and guard the body from infection and damage. However, little is known about their roles outside of host defense in nonbarrier tissues. Here, we characterize a highly enriched tissue-resident population of
Autor:
Daniel J. Drucker, Alexander S. Banks, Bing Lu, Lydia Lynch, Danielle Duquette, Abhisek Ghosh, Donal O'Shea, Andrew E. Hogan, Michael B. Brenner, Eleftheria Maratos-Flier, Michelle Corrigan, David E. Cohen, Chantel Lester, Darko Stevanovic, Katherine B. LeClair
Publikováno v:
Cell Metabolism
Adipose-resident invariant natural killer T (iNKT) cells are key players in metabolic regulation. iNKT cells are innate lipid sensors, and their activation, using their prototypic ligand α-galactosylceramide (αGalCer), induces weight loss and resto
Autor:
Alexander S. Banks, Adam P Uldrich, Ayano C. Kohlgruber, Shani T. Gal-Oz, Hung N. Nguyen, Moto Shimazaki, Tal Shay, Ali Tavakkoli, Amir I. Mina, Ulrich H. von Andrian, Tyler Paras, Dale I. Godfrey, Michael B. Brenner, Nelson M. LaMarche, Danielle Duquette, Hui-Fern Koay, Lydia Lynch
Publikováno v:
Nature Immunology. 20:373-373
In the version of this article initially published, three authors (Hui-Fern Kuoy, Adam P. Uldrich and Dale. I. Godfrey) and their affiliations, acknowledgments and contributions were not included. The correct information is as follows:Ayano C. Kohlgr
Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity
Autor:
Donal B. O’Connor, Desmond Winters, Mark A. Exley, Ali Tavakkoli, Donal O'Shea, Danielle Duquette, Andrew E. Hogan, Suzanne Stutte, David Alvarez, Selma Boulenouar, Lydia Lynch, Xavier Michelet, Michael B. Brenner, Ulrich H. von Andrian, Christina Dold
Publikováno v:
Immunity
Adipose tissue has a dynamic immune system that adapts to changes in diet and maintains homeostatic tissue remodeling. Adipose type 1 innate lymphoid cells (AT1-ILCs) promote pro-inflammatory macrophages in obesity, but little is known about their fu
Autor:
Xavier Michelet, Danielle Duquette, Fumitaka Mizoguchi, Alexander S. Banks, Michael B. Brenner, Victòria Ceperuelo-Mallafré, Kevin Wei, Ayano C. Kohlgruber, Pui Y. Lee, Sook Kyung Chang, Lydia Lynch, Benjamin Wolf
Publikováno v:
The Journal of clinical investigation. 127(9)
M2 macrophages, innate lymphoid type 2 cells (ILC2s), eosinophils, Tregs, and invariant NK T cells (iNKT cells) all help to control adipose tissue inflammation, while M1 macrophages, TNF, and other inflammatory cytokines drive inflammation and insuli
Autor:
Zhao-Ru Dong, Mei Wang, Christian Argueta, Yiming Li, Li Tan, Songmei Geng, Di Hu, Shuyun Xu, Danielle Duquette, Fei Lan, Irfete S. Fetahu, Guoquan Yan, Rui Fang, Ruitu Lv, Jiajia Chen, Yong Ye, Jia Fan, Fei Mao, Guo-Ming Shi, Christine G. Lian, Yufei Xu, Shike Zhang, Pengyuan Yang, Clark Yin, Yujiang Geno Shi, Hang Liu, Lydia Lynch, Di Wu, George F. Murphy, Rajesh Garg, Yang Shi, Hao Chen, Lei Zhang, Feizhen Wu, Gail K. Adler, Kimberlie Rabidou
Publikováno v:
Nature. 559(7715)
Diabetes is a complex metabolic syndrome that is characterized by prolonged high blood glucose levels and frequently associated with life-threatening complications(1,2). Epidemiological studies have suggested that diabetes is also linked to an increa
Autor:
Harrison W. Farber, William W. Cruikshank, Dennis J. Beer, Marcia F. Katz, Yuri A. Romanov, Alexander S. Antonov, Vladimir N. Smirnov, Danielle Duquette
Publikováno v:
Experimental Cell Research. 212:113-119
The development of an extralymphatic T-lymphocyte focus of inflammation requires chemoattractant-induced cell migration and growth factor-induced cell proliferation. In a previous study, we identified a novel 13- to 15-kDa T-lymphocyte-specific chemo