Acellular Perfusate is an Adequate Alternative to Packed Red Blood Cells During Normothermic Human Kidney Perfusion

Autor: Alban Longchamp, MD, PhD, Fermin M. Fontan, MD, Mohamed M. Aburawi, MD, Corey Eymard, MD, Negin Karimian, MD, PhD, Danielle Detelich, MD, Casie Pendexter, BS, Stephanie Cronin, MS, Thomas Agius, MS, Sonal Nagpal, MBA, Peony Dutta Banik, BS, Shannon N. Tessier, PhD, Sinan Ozer, MBA, Francis L. Delmonico, MD, Korkut Uygun, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD

Publikováno v: Transplantation Direct, Vol 10, Iss 4, p e1609 (2024)

Background. Brief normothermic machine perfusion is increasingly used to assess and recondition grafts before transplant. During normothermic machine perfusion, metabolic activity is typically maintained using red blood cell (RBC)–based solutions.

Externí odkaz: https://doaj.org/article/396aa870c24442cab2483459c99fec7e

Normothermic liver preservation, current status and future directions

Autor: Danielle Detelich, James F. Markmann

Publikováno v: Current Opinion in Organ Transplantation. 23:347-352

Purpose of review Normothermic machine perfusion (NMP) is an emerging technology for liver preservation. Early clinical results demonstrate beneficial effects in reconditioning high-risk grafts. This review discusses the role of normothermic perfusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67dfe240cbc6e59d524c7119ac3ed69
https://doi.org/10.1097/mot.0000000000000531

Looking Beyond Diabetes: A Case of Worsening Hyperglycemia as a Manifestation of Ectopic Cushing’s Syndrome Secondary to an Adrenocorticotropic Hormone-Producing Pheochromocytoma

Autor: Kanwal Anwar, Konstantin Balonov, Danielle Detelich, Richard D. Siegel, Ipek Alpertugna, Michael Tarnoff, Jeffrey Vercollone, Ronald M. Lechan, Arthur S. Tischler

Publikováno v: Journal of the Endocrine Society

A 76-year-old woman presented with worsening fasting hyperglycemia on routine blood sugar measurement, previously well-controlled on Metformin, requiring initiation of insulin. Her medical history included type 2 diabetes mellitus, hypertension, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94abe573efbcec18bd1ddb6955294f00
https://doi.org/10.1210/jendso/bvab048.284

PROLONGED SURVIVAL OF GENETICALLY MODIFIED PIG LIVERS DURING MACHINE PERFUSION WITH HUMAN BLOOD

Autor: William F. Westlin, James F. Markmann, Taylor M. Coe, Ivy A. Rosales, Wenning Qin, Rudy Matheson, Cailah Carroll, Luhan Yang, Nikolaos Serifis, Agnes Azimzadeh, Michele Youd, Charles G. Rickert, Shoko Kimura, Jacob V. Layer, Siavash Raigani, Yinan Kan, Danielle Detelich

Publikováno v: Transplantation. 104:S37-S37

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92f431e1187de5d7c0cb50ef550425a0
https://doi.org/10.1097/01.tp.0000698436.68163.75

Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions

Autor: Murat Karabacak, Siavash Raigani, Florence Lin, Negin Karimian, Korkut Uygun, James F. Markmann, Sharon Geerts, Ehab O A Hafiz, Irene Beijert, Danielle Detelich, Viola Huang, Sinan Ozer, Peony D. Banik, Fermin Fontan, Heidi Yeh, Robert J. Porte, Mohamed M. Aburawi

Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 1, p 269 (2020)
Journal of Clinical Medicine, 9(1):269. MDPI AG
Journal of Clinical Medicine
Volume 9
Issue 1

Ex situ machine perfusion is a promising technology to help improve organ viability prior to transplantation. However, preclinical studies using discarded human livers to evaluate therapeutic interventions and optimize perfusion conditions are limite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868bacabc2e0c662c5f407f24f721f1a
https://doi.org/10.3390/jcm9010269