Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Danielle D. Engle"'
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Fig. S1. Primary M2-like macrophages express IGF-1 and IGF-2. Fig. S2. In the absence of chemotherapy, addition of MCM, IGF blockade or recombinant IGF does not affect proliferation or survival of pancreatic cancer cells. Fig.S3. MCM enhances resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06902771ee91c13e027d15cd82063e3a
https://doi.org/10.1158/0008-5472.22412769.v1
https://doi.org/10.1158/0008-5472.22412769.v1
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Supplementary Figure legends. Table S1. Clinical information from 40 consented PDA patient samples. Table S2. Clinical information from 16 consented PDA patient samples. Supplementary Materials and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05193f27a952663e6bd42aea594e452f
https://doi.org/10.1158/0008-5472.22412772.v1
https://doi.org/10.1158/0008-5472.22412772.v1
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Tumor-associated macrophages (TAM) and myofibroblasts are key drivers in cancer that are associated with drug resistance in many cancers, including pancreatic ductal adenocarcinoma (PDAC). However, our understanding of the molecular mechanisms by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767b3c11e3a8231146a3b420547451b4
https://doi.org/10.1158/0008-5472.c.6508512.v1
https://doi.org/10.1158/0008-5472.c.6508512.v1
Autor:
Sonja N. Brun, Gencer Sancar, Jan Lumibao, Allison S. Limpert, Huiyu Ren, Angela Ianniciello, Herve Tiriac, Michael Downes, Danielle D. Engle, Ronald M. Evans, Nicholas D.P. Cosford, Reuben J. Shaw
Amongst cancer subtypes, pancreatic ductal adenocarcinoma (PDA) has been demonstrated to be most sensitive to autophagy inhibition, which may be due to unique metabolic rewiring in these cells. The serine/threonine kinase ULK1 forms the catalytic cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9cd979bb7e86417dcc2356901a2c92
https://doi.org/10.1101/2021.05.15.444304
https://doi.org/10.1101/2021.05.15.444304