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pro vyhledávání: '"Danielle Caruso"'
Publikováno v:
Journal of Molecular Medicine. 97:1627-1641
Recent studies from our group and others have demonstrated that oxidative stress, Ca2+ signaling, and neuroinflammation are major mechanisms contributing to post-traumatic neurodegeneration. The present study investigated the mechanisms of regulation
Publikováno v:
Experimental Neurology. 317:260-270
The blood-brain barrier (BBB) constitutes a neurovascular unit formed by microvascular endothelial cells, pericytes, and astrocytes. Brain pericytes are important regulators of BBB integrity, permeability, and blood flow. Pericyte loss has been impli
Autor:
Veera D’Mello, Christina Finn, Saurav Bhowmick, P. M. Abdul-Muneer, Nizmi Ponery, Anitha Malat, Danielle Caruso
Publikováno v:
eNeuro
Intercellular adhesion molecule-1 (ICAM-1) promotes adhesion and transmigration of circulating leukocytes across the blood-brain barrier. Traumatic brain injury (TBI) causes transmigrated immunocompetent cells to release mediators (LFA-1 and Mac-1) t