Výsledky vyhledávání - "Danielle Caruso"

Traumatic brain injury-induced downregulation of Nrf2 activates inflammatory response and apoptotic cell death

Autor: Danielle Caruso, P. M. Abdul-Muneer, Veera D'Mello, Saurav Bhowmick

Publikováno v: Journal of Molecular Medicine. 97:1627-1641

Recent studies from our group and others have demonstrated that oxidative stress, Ca2+ signaling, and neuroinflammation are major mechanisms contributing to post-traumatic neurodegeneration. The present study investigated the mechanisms of regulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7403e9295dd6b51ceb8b9792782dc982
https://doi.org/10.1007/s00109-019-01851-4

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Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury

Autor: P. M. Abdul-Muneer, Veera D'Mello, Alex Wallerstein, Danielle Caruso, Saurav Bhowmick

Publikováno v: Experimental Neurology. 317:260-270

The blood-brain barrier (BBB) constitutes a neurovascular unit formed by microvascular endothelial cells, pericytes, and astrocytes. Brain pericytes are important regulators of BBB integrity, permeability, and blood flow. Pericyte loss has been impli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa3d22795c6022fb47b4b474be0d054
https://doi.org/10.1016/j.expneurol.2019.03.014

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Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress

Autor: Veera D’Mello, Christina Finn, Saurav Bhowmick, P. M. Abdul-Muneer, Nizmi Ponery, Anitha Malat, Danielle Caruso

Publikováno v: eNeuro

Intercellular adhesion molecule-1 (ICAM-1) promotes adhesion and transmigration of circulating leukocytes across the blood-brain barrier. Traumatic brain injury (TBI) causes transmigrated immunocompetent cells to release mediators (LFA-1 and Mac-1) t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f796f4281367b5719c323dd2256760c
https://doi.org/10.1523/eneuro.0242-21.2021

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