Manipulating the Microbiome: An Alternative Treatment for Bile Acid Diarrhoea

Autor: Evette B. M. Hillman, Sjoerd Rijpkema, Danielle Carson, Ramesh P. Arasaradnam, Elizabeth M. H. Wellington, Gregory C. A. Amos

Publikováno v: Microbiology Research, Vol 12, Iss 2, Pp 335-353 (2021)

Bile acid diarrhoea (BAD) is a widespread gastrointestinal disease that is often misdiagnosed as irritable bowel syndrome and is estimated to affect 1% of the United Kingdom (UK) population alone. BAD is associated with excessive bile acid synthesis

Externí odkaz: https://doaj.org/article/206afc34da2145aa99965d9ff1925bf0

Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines

Autor: Danielle Carson, Sophie Myhill, Elena Palmieri, Francesca Necchi, Sjoerd Rijpkema, Francesca Micoli, Ida Karin Nordgren, Omar Rossi, Caroline Vipond

Publikováno v: Microorganisms, Vol 9, Iss 7, p 1375 (2021)

Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharide

Externí odkaz: https://doaj.org/article/9c99c3bce33e4c9197a514716950ba69

Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines

Autor: Omar Rossi, Danielle Carson, Elena Palmieri, Caroline Vipond, Ida Karin Nordgren, Francesca Micoli, Sjoerd Rijpkema, Francesca Necchi, Sophie Myhill

Publikováno v: Microorganisms, Vol 9, Iss 1375, p 1375 (2021)
Microorganisms
Volume 9
Issue 7

Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5cb066d2aec96a9c2c8b9fd300184
https://www.mdpi.com/2076-2607/9/7/1375

Citrobacter rodentium triggers the rapid onset of conserved infection signatures in a susceptible mouse strain

Autor: Rachael Barry, Danielle Carson, Gad Frankel

Publikováno v: Access Microbiology. 1

Citrobacter rodentium murine infection is the ‘gold standard’ model for investigating host response to human diarrhoeal pathogens, Enteropathogenic and Enterohaemorrhagic Escherichia coli. Mouse strains have varying susceptibility to C. rodentium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b9c78024e3e3639f42d7a4f99311bef
https://doi.org/10.1099/acmi.ac2019.po0223

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

Autor: Gordon Dougan, Ana Elena Pérez-Cobas, Christophe Rusniok, Sandra Reuter, Carmen Buchrieser, Jasmin Demirtas, Shivani Pasricha, Elizabeth L. Hartland, Gunnar N. Schroeder, Gad Frankel, S. Jarraud, Sonia Mondino, Laura Gomez-Valero, Johannes Crumbach, Monica Rolando, Stéphane Descorps-Declère, Danielle Carson

Publikováno v: Gomez-Valero, L, Rusniok, C, Carson, D, Mondino, S, Pérez-Cobas, A E, Rolando, M, Pasricha, S, Reuter, S, Demirtas, J, Crumbach, J, Descorps-Declere, S, Hartland, E L, Jarraud, S, Dougan, G, Schroeder, G N, Frankel, G & Buchrieser, C 2019, ' More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.1808016116, https://doi.org/10.1101/350777
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩

The genus Legionella comprises 65 species, among which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c453963aa5d05c45e4f3bbed371caec
https://pure.qub.ac.uk/en/publications/more-than-18000-effectors-in-the-legionella-genus-genome-provide-multiple-independent-combinations-for-replication-in-human-cells(8cb35736-8923-4ed6-920d-e29c42f7d390).html