Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Danielle Carmignac"'
Autor:
Guillaume Osterstock, Pauline Escobar, Violeta Mitutsova, Laurie-Anne Gouty-Colomer, Pierre Fontanaud, François Molino, Jean-Alain Fehrentz, Danielle Carmignac, Jean Martinez, Nathalie C Guerineau, Iain C A F Robinson, Patrice Mollard, Pierre-François Méry
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9159 (2010)
BACKGROUND:Ghrelin targets the arcuate nucleus, from where growth hormone releasing hormone (GHRH) neurones trigger GH secretion. This hypothalamic nucleus also contains neuropeptide Y (NPY) neurons which play a master role in the effect of ghrelin o
Externí odkaz:
https://doaj.org/article/5627aeb44d88436599b6fd6826f457a7
Autor:
Violeta Mitutsova, Patrice Mollard, Manon Granier, Nikolaus Plesnila, Malcolm J. Low, David J. Hodson, Danielle Carmignac, Marine Chazalon, Iain C. A. F. Robinson, Pierre Fontanaud, Alexander Barre, Pierre François Méry, Guillaume Osterstock
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24394. ⟨10.1038/srep24394⟩
Scientific Reports, 2016, 6, pp.24394. ⟨10.1038/srep24394⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.24394. ⟨10.1038/srep24394⟩
Scientific Reports, 2016, 6, pp.24394. ⟨10.1038/srep24394⟩
Hypothalamic growth hormone-releasing hormone (GHRH) neurons orchestrate body growth/maturation and have been implicated in feeding responses and ageing. However, the electrical patterns that dictate GHRH neuron functions have remained elusive. Since
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb3a92d03253185d0dd04e3f27b5e15
https://doi.org/10.1038/srep24394
https://doi.org/10.1038/srep24394
Autor:
Anne-Cécile Meunier, Jerome Birkenstock, Danielle Carmignac, Chrystel Lafont, Elodie Gavois, Iain C. A. F. Robinson, Paul Le Tissier, Patrice Mollard, David J. Hodson, Joanne F. Murray, Marie Schaeffer
Publikováno v:
Endocrinology
The secretion of endocrine hormones from pituitary cells finely regulates a multitude of homeostatic processes. To dynamically adapt to changing physiological status and environmental stimuli, the pituitary gland must undergo marked structural and fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50d82a7ecd4eb4a638461b92ab389b5
https://doi.org/10.1210/en.2011-1430
https://doi.org/10.1210/en.2011-1430
Autor:
David J. Hodson, Patrice Mollard, Claudia Sánchez-Cárdenas, Marie Schaeffer, Anne-Cécile Meunier, Danielle Carmignac, Xavier Bonnefont, Iain C. A. F. Robinson, Pierre Fontanaud, Zhenhe He, Paul Le Tissier, Elodie Gavois, Nathalie Coutry, Laurie-Anne Gouty-Colomer, François Molino, Chrystel Lafont
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2010, 107 (50), pp.21878-21883. ⟨10.1073/pnas.1010849107⟩
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (50), pp.21878-21883. ⟨10.1073/pnas.1010849107⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2010, 107 (50), pp.21878-21883. ⟨10.1073/pnas.1010849107⟩
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (50), pp.21878-21883. ⟨10.1073/pnas.1010849107⟩
There are well-recognized sex differences in many pituitary endocrine axes, usually thought to be generated by gonadal steroid imprinting of the neuroendocrine hypothalamus. However, the recognition that growth hormone (GH) cells are arranged in func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceaba955ee5ea9ad36e7e615785c2118
https://doi.org/10.1073/pnas.1010849107
https://doi.org/10.1073/pnas.1010849107
Autor:
C. C. Richardson, Iain C.A.F. Robinson, Aileen King, Malcolm J. Low, Astrid C Hauge-Evans, Michael R. Christie, Danielle Carmignac, Shanta J. Persaud, Peter M. Jones
Publikováno v:
Diabetes
OBJECTIVE— Somatostatin (SST) is secreted by islet δ-cells and by extraislet neuroendocrine cells. SST receptors have been identified on α- and β-cells, and exogenous SST inhibits insulin and glucagon secretion, consistent with a role for SST in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263875f84d79fb587298ea15e943deac
https://doi.org/10.2337/db08-0792
https://doi.org/10.2337/db08-0792
Autor:
Isabelle M. Bur, Anne M. Cohen-Solal, Patrice Mollard, Danielle Carmignac, Patrick Maurel, Gijsbertus T. J. van der Horst, Agnès O. Martin, Iain C. A. F. Robinson, Xavier Bonnefont, Norbert Chauvet, Pierre-Yves Abecassis
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2009, 284 (14), pp.9066-73. ⟨10.1074/jbc.M808360200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (14), pp.9066-73. ⟨10.1074/jbc.M808360200⟩
Journal of Biological Chemistry, 284(14), 9066-9073. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 2009, 284 (14), pp.9066-73. ⟨10.1074/jbc.M808360200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (14), pp.9066-73. ⟨10.1074/jbc.M808360200⟩
Journal of Biological Chemistry, 284(14), 9066-9073. American Society for Biochemistry and Molecular Biology Inc.
International audience; In mammals, males and females exhibit anatomical, hormonal, and metabolic differences. A major example of such sex dimorphism in mouse involves hepatic drug metabolism, which is also a noticeable target of circadian timekeepin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c30423b04b2898409ab1e09af1e733
https://doi.org/10.1074/jbc.M808360200
https://doi.org/10.1074/jbc.M808360200
Autor:
Rachel L. Batterham, Dominic J. Withers, Faruk Ramadani, Eric Blanc, Eugene Schuster, Iain C. A. F. Robinson, Hind Al-Qassab, David Gems, Matthew D.W. Piper, Janet M. Thornton, Melanie Clements, Colin Selman, John R. Speakman, Danielle Carmignac, Klaus Okkenhaug, Marc Claret, Steven J. Lingard, Agharul I. Choudhury, Linda Partridge
Publikováno v:
The FASEB Journal. 22:807-818
Recent evidence suggests that alterations in insulin/insulin-like growth factor 1 (IGF1) signaling (IIS) can increase mammalian life span. For example, in several mouse mutants, impairment of the growth hormone (GH)/IGF1 axis increases life span and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8659df51a003098ef1831d1874ad54f4
https://doi.org/10.1096/fj.07-9261com
https://doi.org/10.1096/fj.07-9261com
Autor:
Patrice Mollard, Danielle Carmignac, Catherine Loudes, Angela Sanchez-Hormigo, Bénédicte Recolin, Pierre-François Méry, Annie Faivre-Bauman, Jacques Epelbaum, Gérard Alonso, Taoufik El Yandouzi, Iain C. A. F. Robinson
Publikováno v:
Aging Cell. 6:197-207
Growth hormone (GH) secretion decreases spontaneously during lifespan, and the resulting GH deficiency participates in aging-related morbidity. This deficiency appears to involve a defect in the activity of hypothalamic GH-releasing hormone (GHRH) ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193fe13367290b9eb8792f00fae9e3d3
https://doi.org/10.1111/j.1474-9726.2007.00276.x
https://doi.org/10.1111/j.1474-9726.2007.00276.x
Autor:
Pierre Fontanaud, Nathalie Courtois-Coutry, Alain Lacampagne, Gérard Alonso, Danielle Carmignac, Pierre Travo, Xavier Bonnefont, Steve M. Pincus, Elodie Fino, Audrey Creff, Iain C. A. F. Robinson, Marie-Noëlle Mathieu, Angela Sanchez-Hormigo, Sébastien A. Smallwood, Patrice Mollard
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2005, 102, pp.16880-16885. ⟨10.1073/pnas.0508202102⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2005, 102, pp.16880-16885. ⟨10.1073/pnas.0508202102⟩
Pituitary growth hormone (GH)-secreting cells regulate growth and metabolism in animals and humans. To secrete highly ordered GH pulses (up to 1,000-fold rise in hormone levels in vivo ), the pituitary GH cell population needs to mount coordinated re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d5e794d76bd770ebb87dfcbf8ad74e
https://doi.org/10.1073/pnas.0508202102
https://doi.org/10.1073/pnas.0508202102
Autor:
Abdul K. Sesay, Lindsay McGuinness, Helen C. Christian, John A. Phillips, Charalambos Magoulas, Jean-Baptiste Manneville, Danielle Carmignac, Kathleen Mathers, Iain C. A. F. Robinson
Publikováno v:
Endocrinology. 144:720-731
Autosomal dominant GH deficiency type II (IGHDII) is often associated with mutations in the human GH gene (GH1) that give rise to products lacking exon-3 ((Deltaexon3)hGH). In the heterozygous state, these act as dominant negative mutations that prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66dadad5ef3eb2ddfb713f51458468a
https://doi.org/10.1210/en.2002-220847
https://doi.org/10.1210/en.2002-220847