Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Danielle Califano"'
Autor:
George Huang, Denise Sullivan, Sayem H Bhuiyan, Danielle Califano, Stacie Chvatal, Daniel Millard
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ce839fde5eb74933b151978da97fa86c
Autor:
Jonathan J. Cho, Zhiwei Xu, Upasana Parthasarathy, Theodore T. Drashansky, Eric Y. Helm, Ashley N. Zuniga, Kyle J. Lorentsen, Samira Mansouri, Joshua Y. Cho, Mariola J. Edelmann, Duc M. Duong, Torben Gehring, Thomas Seeholzer, Daniel Krappmann, Mohammad N. Uddin, Danielle Califano, Rejean L. Wang, Lei Jin, Hongmin Li, Dongwen Lv, Daohong Zhou, Liang Zhou, Dorina Avram
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Ubiquitination may control protein stability or function. Here the authors show that an ubiquitination enzyme, Hectd3, ubiquitinates Stat3 and Malt1 to modulate their function but not degradation in T cells, and thereby promoting the differentiation
Externí odkaz:
https://doaj.org/article/1894c8d823ab4177ab03857c322a339c
Autor:
Tarani Kanta Barman, Rachael Racine, Jesse L Bonin, Danielle Califano, Sharon L Salmon, Dennis W Metzger
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009405 (2021)
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly unders
Externí odkaz:
https://doaj.org/article/330e733cd7554e13bdb11b1f3afaac28
Autor:
Tarani Kanta Barman, Victor C. Huber, Jesse L. Bonin, Danielle Califano, Sharon L. Salmon, Andrew N. J. McKenzie, Dennis W. Metzger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
SignificanceThe regulation of functional immune cell plasticity is poorly understood. Host environmental cues are critical, but the possible influence of pathogen-derived virulence factors has not been described. We have used reverse-engineered influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f92e27ae84e65a44a8347f88ae45d79
https://pubmed.ncbi.nlm.nih.gov/35169077
https://pubmed.ncbi.nlm.nih.gov/35169077
Autor:
Sreeja Roy, Andrew N. J. McKenzie, Clare M Williams, Yoichi Furuya, Danielle Califano, Dennis W. Metzger
Publikováno v:
J Virol
Interleukin-33 (IL-33) is a multifunctional cytokine that mediates type 2-dominated immune responses. In contrast, the role of IL-33 during viral vaccination, which often aims to induce type 1 immunity, has not been fully investigated. Here, we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee587cc6432e356ce95e2263d71de45c
https://pubmed.ncbi.nlm.nih.gov/34468174
https://pubmed.ncbi.nlm.nih.gov/34468174
Autor:
Dorina Avram, Rejean L. Wang, Hongmin Li, Upasana Parthasarathy, Torben Gehring, Thomas Seeholzer, Daniel Krappmann, Mohammad N. Uddin, Lei Jin, Liang Zhou, Dongwen Lv, Eric Y. Helm, Jonathan J. Cho, Duc M. Duong, Kyle J. Lorentsen, Theodore T. Drashansky, Danielle Califano, Samira Mansouri, Mariola J. Edelmann, Daohong Zhou, Zhiwei Xu, Joshua Y. Cho, Ashley N. Zuniga
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications
Nat. Commun. 10:701 (2019)
Nature Communications
Nat. Commun. 10:701 (2019)
Polyubiquitination promotes proteasomal degradation, or signaling and localization, of targeted proteins. Here we show that the E3 ubiquitin ligase Hectd3 is necessary for pathogenic Th17 cell generation in experimental autoimmune encephalomyelitis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483c070db342678c4ea9656aa2aaf78b
http://link.springer.com/article/10.1038/s41467-019-08605-3
http://link.springer.com/article/10.1038/s41467-019-08605-3
Autor:
Rachael Racine, Jesse L. Bonin, Sharon L. Salmon, Tarani Kanta Barman, Dennis W. Metzger, Danielle Califano
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009405 (2021)
PLoS Pathogens
PLoS Pathogens
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caa048d9c4247b389ed90fc3bab105a
https://doaj.org/article/330e733cd7554e13bdb11b1f3afaac28
https://doaj.org/article/330e733cd7554e13bdb11b1f3afaac28
Publikováno v:
The Journal of Immunology. 204:148.38-148.38
Influenza remains a major public health concern. The H1N1 PR8 and CA04 influenza viruses are both pandemic strains, yet they have distinct origins and pathogenicity. In PR8, the PB1-F2 viral protein promotes apoptosis of immune cells and negatively i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3cd73e4cd158d806c1ce104c321b7ec
https://doi.org/10.4049/jimmunol.204.supp.148.38
https://doi.org/10.4049/jimmunol.204.supp.148.38
Secondary bacterial coinfections following influenza virus pose a serious threat to human health. Therefore, it is of significant clinical relevance to understand the immunological causes of this increased susceptibility. Influenza-induced alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf9546a9d155cf0c3748a4bbddbdb8c
https://europepmc.org/articles/PMC6008236/
https://europepmc.org/articles/PMC6008236/
Autor:
Danielle Califano, Dorina Avram
Publikováno v:
The Journal of Immunology. 193:2059-2065
The transcription factor Bcl11b is expressed in all T cell subsets and progenitors, starting from the DN2 stage of T cell development, and it regulates critical processes implicated in the development, function, and survival of many of these cells. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc55ef61c36b1d573dc926814eb640d3
https://doi.org/10.4049/jimmunol.1400930
https://doi.org/10.4049/jimmunol.1400930