Predicting Malignancy in Pediatric Thyroid Nodules: Early Experience with Machine Learning for Clinical Decision Support

Autor: Jonathan D. Wasserman, Lebohang Radebe, Danielle C. M. van der Kaay, Anna Goldenberg

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 106(12), E5236-E5246. Endocrine Society

Objective To develop a machine learning tool to integrate clinical data for the prediction of non-benign thyroid cytology and histology. Context Papillary thyroid carcinoma is the most common endocrine malignancy. Since most nodules are benign, the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82ab313d92a64c83d44b5a208c84943
https://pure.eur.nl/en/publications/e3ccf812-2d25-4da4-96d4-c99bad2b4b13

Insulin Sensitivity and beta-Cell Function in SGA Children Treated With GH and GnRHa: Results of a Long-Term Trial

Autor: Manouk van der Steen, Annemieke J. Lem, Anita C. S. Hokken-Koelega, Danielle C. M. van der Kaay

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 101(2), 705-713. Endocrine Society

Pubertal children born small for gestational age with a poor adult height (AH) expectation can benefit from treatment with GH 1 mg/m(2)/d (∼0.033 mg/kg/d) in combination with 2 years of GnRH analog (GnRHa) and even more so with GH 2 mg/m(2)/d. Beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37c02b8efa16ac4b86e9c8b1d02e13c
https://pure.eur.nl/en/publications/678ac7a8-8528-451a-bf66-73649a7dc648

Metabolic Health in Short Children Born Small for Gestational Age Treated With Growth Hormone and Gonadotropin-Releasing Hormone Analog: Results of a Randomized, Dose-Response Trial

Autor: Anita C. S. Hokken-Koelega, R. J. Odink, Manouk van der Steen, Floor S. Neijens, Willie M. Bakker-van Waarde, Ciska Westerlaken, Danielle C. M. van der Kaay, Cees Noordam, Annemieke J. Lem, Flip J. P. C. M. van der Hulst, Wilma Oostdijk, E J Schroor

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 100, 10, pp. 3725-34
Journal of Clinical Endocrinology and Metabolism, 100(10), 3725-3734. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 100(10), 3725-3734
Journal of Clinical Endocrinology and Metabolism, 100, 3725-34
Journal of Clinical Endocrinology and Metabolism, 100(10), 3725-3734. ENDOCRINE SOC

Item does not contain fulltext CONTEXT: Previously we showed that pubertal children born small for gestational age (SGA) with a poor adult height (AH) expectation can benefit from treatment with GH 1 mg/m(2) per day ( approximately 0.033 mg/kg/d) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad2200c4c4134f6dad2487893fc8ba6
https://doi.org/10.1210/jc.2015-2619

Management of Neonates Born to Mothers With Graves’ Disease

Autor: Danielle C. M. van der Kaay, Jonathan D. Wasserman, Mark R. Palmert

Publikováno v: Pediatrics. 137

Neonates born to mothers with Graves’ disease are at risk for significant morbidity and mortality and need to be appropriately identified and managed. Because no consensus guidelines regarding the treatment of these newborns exist, we sought to gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b928e12e4217e4db8ce6fd7a24522401
https://doi.org/10.1542/peds.2015-1878

Randomized GH trial with two different dosages in combination with a GnRH analogue in short small for gestational age children: effects on metabolic profile and serum GH, IGF1, and IGFBP3 levels

Autor: Inge Rowaan, Jaap Mulder, Merel Willeboer, Danielle C. M. van der Kaay, Maria A. J. de Ridder, Flip J. P. C. M. van der Hulst, Denise van Elswijk, Dick Mul, Boudewijn Bakker, Anita C. S. Hokken-Koelega, E J Schroor

Publikováno v: European Journal of Endocrinology, 162(5), 887-895. Bioscientifica Ltd

BackgroundGnRH analogue (GnRHa) combined with GH treatment has been proposed to increase adult height. Effect on metabolic profile and GH, IGF1, and IGFBP3 levels in short small for gestational age (SGA) children is unknown.ObjectiveTo assess fat mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeba17850b9c94ef8761b041653b6d6
https://doi.org/10.1530/EJE-09-1113