Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Danielle C Spitzer"'
AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
Autor:
Carlos P Descovich, Kendall J Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C Spitzer, Manuela Uppalapati, Katarzyna M Kedziora, Scott E Williams
Publikováno v:
eLife, Vol 12 (2023)
Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the distribution of division angles among basal keratinocyte progenitors is bimodal, with plana
Externí odkaz:
https://doaj.org/article/a0bb50460c8e4723a4d8a41ba4e782f4
Autor:
Thibaut Brunet, Marvin Albert, William Roman, Maxwell C Coyle, Danielle C Spitzer, Nicole King
Publikováno v:
eLife, Vol 10 (2021)
Amoeboid cell types are fundamental to animal biology and broadly distributed across animal diversity, but their evolutionary origin is unclear. The closest living relatives of animals, the choanoflagellates, display a polarized cell architecture (wi
Externí odkaz:
https://doaj.org/article/eb91b66f99144b5abd0c4b481927da0d
Autor:
Kendall J Lough, Kevin M Byrd, Carlos P Descovich, Danielle C Spitzer, Abby J Bergman, Gerard MJ Beaudoin III, Louis F Reichardt, Scott E Williams
Publikováno v:
eLife, Vol 8 (2019)
During organogenesis, precise control of spindle orientation balances proliferation and differentiation. In the developing murine epidermis, planar and perpendicular divisions yield symmetric and asymmetric fate outcomes, respectively. Classically, d
Externí odkaz:
https://doaj.org/article/dc7ad15b2e494f039193f5433ed8fe41
Autor:
Carlos P Descovich, Kendall J Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C Spitzer, Manuela Uppalapati, Katarzyna M Kedziora, Scott E Williams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e691c847c33d38e4a3665a72061041a
https://doi.org/10.7554/elife.80403.sa2
https://doi.org/10.7554/elife.80403.sa2
Autor:
Nicole King, Maxwell C Coyle, Marvin Albert, Danielle C. Spitzer, William Roman, Thibaut Brunet
Publikováno v:
eLife, Vol 10 (2021)
Amoeboid cell types are fundamental to animal biology and broadly distributed across animal diversity, but their evolutionary origin is unclear. The closest living relatives of animals, the choanoflagellates, display a polarized cell architecture (wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff64855364660df6afc2e658246a299d
https://escholarship.org/uc/item/3382g622
https://escholarship.org/uc/item/3382g622
The evolution of different cell types was a key process of early animal evolution1–3. Two fundamental cell types, epithelial cells and amoeboid cells, are broadly distributed across the animal tree of life4,5but their origin and early evolution are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b0a1832184b1e9bfb6114bc21ade14
https://doi.org/10.1101/2020.06.26.171736
https://doi.org/10.1101/2020.06.26.171736
Autor:
Danielle C. Spitzer, Kendall J. Lough, Jessica J. Wu, Abby J. Bergman, Kevin M. Byrd, Scott E. Williams
Publikováno v:
Development
Cleft palate (CP), one of the most common congenital diseases, arises from failures in secondary palatogenesis during embryonic development. Several human genetic syndromes featuring CP and ectodermal dysplasia have been linked to mutations in genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69f18b4c3132f416bccc629567c68b7
https://doi.org/10.1242/dev.189241
https://doi.org/10.1242/dev.189241
Autor:
Danielle C. Spitzer, Kara A. DeSantis, Deirdre A. Nelson, Adam R. Stabell, Melinda Larsen, Kevin J. O'Keefe
Publikováno v:
Organogenesis. 13:125-140
Understanding the mechanisms of controlled expansion and differentiation of basal progenitor cell populations during organogenesis is essential for developing targeted regenerative therapies. Since...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d1dcbe38a61dee7e80b89fd1942000
https://doi.org/10.1080/15476278.2017.1358336
https://doi.org/10.1080/15476278.2017.1358336
Autor:
Gerard M.J. Beaudoin, Carlos Patino Descovich, Louis F. Reichardt, Scott E. Williams, Danielle C. Spitzer, Kevin M. Byrd, Kendall J. Lough, Abby J. Bergman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::575225929cd6188a4737add404e169cd
https://doi.org/10.7554/elife.49249.sa2
https://doi.org/10.7554/elife.49249.sa2