Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Danielle Bonardelle"'
Autor:
Ingrid Durand-Gasselin, Pierre Bobé, Emmanuelle Soual-Hoebeke, Nicole Kiger, Dominique Emilie, Danielle Bonardelle, Karim Benihoud
Publikováno v:
Oncogene. 21:5593-5600
LINE-1 are endogenous mobile genetic elements that have dispersed and accumulated in the genomes of eukaryotes via germline transposition, with up to 100,000 copies in mammalian genomes. LINE-1 elements transpose by reverse transcription of their own
Publikováno v:
European Journal of Immunology. 27:415-420
Autoimmune-prone MRL/lpr mice, homozygous for the lpr mutation, exhibit defective apoptosis and develop generalized lymphoproliferation with the accumulation of a double-negative (DN: CD4- CD8-) T cell population. The capacity of lpr T lymphocytes to
Autor:
Elisabeth Connault, Barbara Salone, Paule Opolon, Michel Perricaudet, Delphyne Descamps, Pierre Bobé, Stéphanie Esselin, Karim Benihoud, Isabella Saggio, Danielle Bonardelle, Betsy Jullienne
Publikováno v:
Gene Ther
Gene Ther, 2007, 14 (6), pp.551. ⟨10.1038/sj.gt.3302909⟩
Gene Therapy
Gene Therapy, Nature Publishing Group, 2007, 14 (6), pp.533-544. ⟨10.1038/sj.gt.3302885⟩
Gene Ther, 2007, 14 (6), pp.551. ⟨10.1038/sj.gt.3302909⟩
Gene Therapy
Gene Therapy, Nature Publishing Group, 2007, 14 (6), pp.533-544. ⟨10.1038/sj.gt.3302885⟩
International audience; The immunogenicity of recombinant adenoviruses (Ad) constitutes a major concern for their use in gene therapy. Antibody- and cell-mediated immune responses triggered by adenoviral vectors hamper long-term transgene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d02adae38b0564567e86d0c0b0988bf
http://hdl.handle.net/20.500.12278/119636
http://hdl.handle.net/20.500.12278/119636
Publikováno v:
Blood
Blood, American Society of Hematology, 2006, 108 (13), pp.3967-75. ⟨10.1182/blood-2006-04-020610⟩
Blood, 2006, 108 (13), pp.3967-75. ⟨10.1182/blood-2006-04-020610⟩
Blood, American Society of Hematology, 2006, 108 (13), pp.3967-75. ⟨10.1182/blood-2006-04-020610⟩
Blood, 2006, 108 (13), pp.3967-75. ⟨10.1182/blood-2006-04-020610⟩
MRL/lpr mice develop a human lupuslike syndrome and, as in autoimmune lymphoproliferative syndrome (ALPS), massive lymphoproliferation due to inactivation of Fas-mediated apoptosis. Presently, no effective therapy exists for ALPS, and long term, ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0024321d1150312b6c95f962a53d11
https://www.hal.inserm.fr/inserm-00091644
https://www.hal.inserm.fr/inserm-00091644
Publikováno v:
Journal of leukocyte biology. 78(5)
The Fas/Fas ligand (FasL) pathway is one of the two major effector mechanisms of T cell-mediated cytotoxicity. To prevent nonspecific killing by lymphoid cells, FasL expression on the cell surface of immune effector cells is strictly regulated. Howev