Výsledky vyhledávání - "Danielle Barbosa Brotto"

Akademický článek

CeTF: an R/Bioconductor package for transcription factor co-expression networks using regulatory impact factors (RIF) and partial correlation and information (PCIT) analysis

Autor: Carlos Alberto Oliveira de Biagi, Ricardo Perecin Nociti, Danielle Barbosa Brotto, Breno Osvaldo Funicheli, Patrícia de Cássia Ruy, João Paulo Bianchi Ximenez, David Livingstone Alves Figueiredo, Wilson Araújo Silva

Publikováno v: BMC Genomics, Vol 22, Iss 1, Pp 1-8 (2021)

Abstract Background Finding meaningful gene-gene interaction and the main Transcription Factors (TFs) in co-expression networks is one of the most important challenges in gene expression data mining. Results Here, we developed the R package “CeTF�

Externí odkaz: https://doaj.org/article/0831f2553a8d44cbaaa1a98f7648ac91

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Akademický článek

Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population

Autor: Simone da Costa e Silva Carvalho, Nathalia Moreno Cury, Danielle Barbosa Brotto, Luiza Ferreira de Araujo, Reginaldo Cruz Alves Rosa, Lorena Alves Texeira, Jessica Rodrigues Plaça, Adriana Aparecida Marques, Kamila Chagas Peronni, Patricia de Cássia Ruy, Greice Andreotti Molfetta, Julio Cesar Moriguti, Dirce Maria Carraro, Edenir Inêz Palmero, Patricia Ashton-Prolla, Victor Evangelista de Faria Ferraz, Wilson Araujo Silva Jr

Publikováno v: BMC Medical Genomics, Vol 13, Iss 1, Pp 1-24 (2020)

Abstract Background The Hereditary Breast and Ovarian Cancer Syndrome (HBOC) occurs in families with a history of breast/ovarian cancer, presenting an autosomal dominant inheritance pattern. BRCA1 and BRCA2 are high penetrance genes associated with a

Externí odkaz: https://doaj.org/article/7017c847d5db4a25b8ac154488e75410

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Akademický článek

Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review

Autor: Danielle Barbosa Brotto, Ádamo Davi Diógenes Siena, Isabela Ichihara de Barros, Simone da Costa e Silva Carvalho, Bruna Rodrigues Muys, Lucas Goedert, Cibele Cardoso, Jessica Rodrigues Plaça, Anelisa Ramão, Jeremy Andrew Squire, Luiza Ferreira Araujo, Wilson Araújo da Silva

Publikováno v: Tumor Biology, Vol 42 (2020)

Homeobox genes function as master regulatory transcription factors during development, and their expression is often altered in cancer. The HOX gene family was initially studied intensively to understand how the expression of each gene was involved i

Externí odkaz: https://doaj.org/article/ed091ebde5264aefb7a51bb29eb25d49

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Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population

Autor: Lorena Alves Texeira, Simone da Costa e Silva Carvalho, Patrícia de Cássia Ruy, Nathalia Moreno Cury, Victor Evangelista de Faria Ferraz, Wilson A. Silva, Reginaldo Cruz Alves Rosa, Danielle Barbosa Brotto, Luiza Ferreira de Araújo, Dirce Maria Carraro, Patricia Ashton-Prolla, Julio Cesar Moriguti, Edenir Inêz Palmero, Kamila Chagas Peronni, Adriana Aparecida Marques, Jessica Rodrigues Plaça, Greice Andreotti de Molfetta

Publikováno v: BMC Medical Genomics, Vol 13, Iss 1, Pp 1-24 (2020)
BMC Medical Genomics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

BackgroundThe Hereditary Breast and Ovarian Cancer Syndrome (HBOC) occurs in families with a history of breast/ovarian cancer, presenting an autosomal dominant inheritance pattern.BRCA1andBRCA2are high penetrance genes associated with an increased ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c853fb09c2bbbc4de4e3b7870a10868
https://doaj.org/article/7017c847d5db4a25b8ac154488e75410

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Non-Syndromic Intellectual Disability and Its Pathways: A Long Noncoding RNA Perspective

Autor: Jessica Oliveira Santis, Reginaldo Cruz Alves Rosa, Danielle Barbosa Brotto, Greice Andreotti de Molfetta, Wilson A. Silva, I. I. Barros, Camila Baldin Storti, Vitor Leão, Ádamo Davi Diógenes Siena

Publikováno v: Non-Coding RNA, Vol 7, Iss 22, p 22 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Non-Coding RNA

Non-syndromic intellectual disability (NS-ID or idiopathic) is a complex neurodevelopmental disorder that represents a global health issue. Although many efforts have been made to characterize it and distinguish it from syndromic intellectual disabil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dedf19c2e6697deb8f543db78f7e190
https://www.mdpi.com/2311-553X/7/1/22

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CeTF: an R/Bioconductor package for transcription factor co-expression networks using regulatory impact factors (RIF) and partial correlation and information (PCIT) analysis

Autor: Breno Osvaldo Funicheli, Wilson A. Silva, David Livingstone Alves Figueiredo, Carlos Alberto Oliveira de Biagi, Ricardo Perecin Nociti, Patrícia de Cássia Ruy, João Paulo Bianchi Ximenez, Danielle Barbosa Brotto

Publikováno v: BMC Genomics
BMC Genomics, Vol 22, Iss 1, Pp 1-8 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background Finding meaningful gene-gene interaction and the main Transcription Factors (TFs) in co-expression networks is one of the most important challenges in gene expression data mining. Results Here, we developed the R package “CeTF” that in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c2ee495422aa830c0f78de9a14b032
https://pubmed.ncbi.nlm.nih.gov/34416858

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Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review

Autor: Anelisa Ramão, Cibele Cardoso, Simone da Costa e Silva Carvalho, Wilson A. Silva, Lucas Goedert, Bruna Rodrigues Muys, Danielle Barbosa Brotto, Jessica Rodrigues Plaça, Jeremy A. Squire, Luiza Ferreira de Araújo, I. I. Barros, Ádamo Davi Diógenes Siena

Publikováno v: Tumor Biology, Vol 42 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d385253e7bf8537b4973e2c9c339d3
https://doi.org/10.1177/1010428320918050

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Mitochondrial transcription factor A (TFAM) shapes metabolic and invasion gene signatures in melanoma

Autor: Andréia Machado Leopoldino, Greice Andreotti de Molfetta, Wilson A. Silva, L. C. West, Josane de Freitas Sousa, I. I. Barros, Luiza Ferreira de Araújo, Jessica Rodrigues Plaça, Ádamo Davi Diógenes Siena, Kamila Chagas Peronni, A. P. West, Danielle Barbosa Brotto, Enilza Maria Espreáfico, Carlos Alberto Oliveira de Biagi, Bruna Rodrigues Muys

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)

Mitochondria are central key players in cell metabolism, and mitochondrial DNA (mtDNA) instability has been linked to metabolic changes that contribute to tumorigenesis and to increased expression of pro-tumorigenic genes. Here, we use melanoma cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc942fd95395eecc5dd6526dcd4ddc71
https://pubmed.ncbi.nlm.nih.gov/30242167

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