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pro vyhledávání: '"Danielle Algranati"'
Autor:
Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander Plotnikov, Haim Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth, Efrat Shema
Publikováno v:
eLife, Vol 13 (2024)
Diffuse midline gliomas (DMGs) are aggressive and fatal pediatric tumors of the central nervous system that are highly resistant to treatments. Lysine to methionine substitution of residue 27 on histone H3 (H3-K27M) is a driver mutation in DMGs, resh
Externí odkaz:
https://doaj.org/article/d63328b5980f4190895f7d76cb98e2cf
Autor:
Noa Furth, Danielle Algranati, Bareket Dassa, Olga Beresh, Vadim Fedyuk, Natasha Morris, Lawryn H. Kasper, Dan Jones, Michelle Monje, Suzanne J. Baker, Efrat Shema
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110836- (2022)
Summary: Cancer-associated mutations in genes encoding histones dramatically reshape chromatin and support tumorigenesis. Lysine to methionine substitution of residue 27 on histone H3 (K27M) is a driver mutation in high-grade pediatric gliomas, known
Externí odkaz:
https://doaj.org/article/117f2901cfb8476fbc341b4a3a4df1bc
Autor:
Efrat Shema, Bareket Dassa, Michelle Monje, Lawryn H. Kasper, Suzanne J. Baker, Natasha Morris, Danielle Algranati, Vadim Fedyuk, Noa Furth, Olga Beresh, Daniel S. Jones
Publikováno v:
Cell Reports. 39(7):110836
Cancer-associated mutations in genes encoding histones dramatically reshape chromatin and support tumorigenesis. Lysine to methionine substitution of residue 27 on histone H3 (K27M) is a driver mutation in high-grade pediatric gliomas, known to abrog