Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Danielle A. Simmons"'
Autor:
Selena Gonzalez, Tyne L.M. McHugh, Tao Yang, Wassim Syriani, Stephen M. Massa, Frank M. Longo, Danielle A. Simmons
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105563- (2022)
Degeneration of basal forebrain cholinergic neurons (BFCNs) in the nucleus basalis of Meynert (NBM) and vertical diagonal band (VDB) along with their connections is a key pathological event leading to memory impairment in Alzheimer's disease (AD). Ab
Externí odkaz:
https://doaj.org/article/a0db4b9385924e2193f56f5fbddd78f9
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 436-444 (2011)
Daily, systemic injections of a positive AMPA-type glutamate receptor modulator (ampakine) have been shown to reduce synaptic plasticity defects in rodent models of aging and early-stage Huntington's disease (HD). Here we report that long-term ampaki
Externí odkaz:
https://doaj.org/article/bd8d2fe0cf1a481f8de35ffef1d30b5d
Autor:
Julia K. Carmody, Kara McRae Duraccio, Kendra N. Krietsch, Danielle M. Simmons, Kelly C. Byars
Publikováno v:
Sleep medicine. 101
Adherence to positive airway pressure (PAP) treatment among children and adolescents is often suboptimal. Little is understood about modifiable determinants of PAP adherence. We evaluated whether patient and caregiver-perceived treatment barriers (ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ce5ea6ebf5e14efdc379cd41a9520e
https://pubmed.ncbi.nlm.nih.gov/36335892
https://pubmed.ncbi.nlm.nih.gov/36335892
Autor:
Maged Grouban, Danielle A. Simmons, Michael Zeineh, Tyne L.M. McHugh, Frank M. Longo, Robert R. Butler, Jason Kuan, Wassim Syriani, Carolyn Akers, Brian D. Mills, James Zhou
Publikováno v:
Neurotherapeutics
Huntington’s disease (HD) is caused by an expansion of the CAG repeat in the huntingtin gene leading to preferential neurodegeneration of the striatum. Disease-modifying treatments are not yet available to HD patients and their development would be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd298578b2f550acdbba6ccb5b45db97
http://europepmc.org/articles/PMC8423954
http://europepmc.org/articles/PMC8423954
Autor:
Melissa Jenkins, Anna Kim, Ryan B. Ko, Selena Gonzalez, Gregory King, Rie von Eyben, Marjan Rafat, Edward E. Graves, Billy W. Loo, Peter G. Maxim, Danielle A. Simmons, Jinghui Wang, Emil Schüler, Frederick M. Lartey, Sarah Semaan, Frank M. Longo, P. Pradhan, Zion Shih
Publikováno v:
Radiotherapy and Oncology. 139:4-10
Aim To evaluate the impact of ultra-rapid FLASH mouse whole brain irradiation on hippocampal dendritic spines and neuroinflammation, factors associated with cognitive impairment after brain irradiation. Methods We administered 30 Gy whole brain irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad38553d774fa146321e79a7fb8c255
https://doi.org/10.1016/j.radonc.2019.06.006
https://doi.org/10.1016/j.radonc.2019.06.006
Autor:
Peter A. Smith, Klaus Ballanyi, Vladimir Rancic, Frank M. Longo, Kerri H. Whitlock, Paul A. Boakye, Danielle A. Simmons
Publikováno v:
Journal of Neurophysiology. 121:2308-2322
Peripheral nerve injury elicits an enduring increase in the excitability of the spinal dorsal horn. This change, which contributes to the development of neuropathic pain, is a consequence of release and prolonged exposure of dorsal horn neurons to va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507450f94c6c016ad7398c467372cbdc
https://doi.org/10.1152/jn.00839.2018
https://doi.org/10.1152/jn.00839.2018
Autor:
Danielle A Simmons, Juliet K Knowles, Nadia P Belichenko, Gargi Banerjee, Carly Finkle, Stephen M Massa, Frank M Longo
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e102136 (2014)
Degeneration of basal forebrain cholinergic neurons contributes significantly to the cognitive deficits associated with Alzheimer's disease (AD) and has been attributed to aberrant signaling through the neurotrophin receptor p75 (p75NTR). Thus, modul
Externí odkaz:
https://doaj.org/article/ce298275ec274c88bc28dc54ea0e96ff
Autor:
Danielle A. Simmons
Publikováno v:
Journal of Huntington's Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansions in the IT15 gene which encodes the huntingtin (HTT) protein. Currently, no treatments capable of preventing or slowing disease progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad30b8bae3c6e796205f461a5f94826
https://doi.org/10.3233/jhd-170275
https://doi.org/10.3233/jhd-170275
Autor:
Theodore M. Webster, David C. Bridges, Danielle B. Simmons, Brian T. Scully, Timothy L. Grey, A. Stanley Culpepper
Publikováno v:
Field Crops Research. 192:103-109
Herbicide resistant Palmer amaranth (Amaranthus palmeri) has rapidly become a dominant weed management issue in agronomic crops of the Southeast US. The small size of Palmer amaranth seeds, relative to other common weeds, provides an opportunity to u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7286c9e9981970e569e00ba81f471b8d
https://doi.org/10.1016/j.fcr.2016.04.020
https://doi.org/10.1016/j.fcr.2016.04.020
Autor:
Deqiang Jing, Marie Monbureau, Christina Condon, Nadia P. Belichenko, Stephen M. Massa, Tao Yang, Mehrdad Shamloo, Danielle A. Simmons, Frank M. Longo
Publikováno v:
The Journal of Neuroscience. 33:18712-18727
Loss of neurotrophic support in the striatum caused by reduced brain-derived neurotrophic factor (BDNF) levels plays a critical role in Huntington's disease (HD) pathogenesis. BDNF acts via TrkB and p75 neurotrophin receptors (NTR), and restoring its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8080bdc09d7fed11fab0ccdbeee64a6
https://doi.org/10.1523/jneurosci.1310-13.2013
https://doi.org/10.1523/jneurosci.1310-13.2013