Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Danielle A. Becktel"'
Autor:
Danielle A. Becktel, Jennifer B. Frye, Elizabeth H. Le, Susan A. Whitman, Rick G. Schnellmann, Helena W. Morrison, Kristian P. Doyle
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100614- (2024)
Ischemic stroke remains a leading cause of mortality and long-term disability worldwide, necessitating efforts to identify biomarkers for diagnosis, prognosis, and treatment monitoring. The present study aimed to identify novel plasma biomarkers of n
Externí odkaz:
https://doaj.org/article/feeba4deab6342fbba07121e68c902ff
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106130- (2023)
Inflammation is a crucial part of the healing process after an ischemic stroke and is required to restore tissue homeostasis. However, the inflammatory response to stroke also worsens neurodegeneration and creates a tissue environment that is unfavor
Externí odkaz:
https://doaj.org/article/0f7ad81c9c6742ebb64291b5dce662fa
Autor:
Sanna H. Loppi, Marco A. Tavera-Garcia, Natalie E. Scholpa, Boaz K. Maiyo, Danielle A. Becktel, Helena W. Morrison, Rick G. Schnellmann, Kristian P. Doyle
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16632 (2023)
Following ischemic stroke, the degradation of myelin and other cellular membranes surpasses the lipid-processing capabilities of resident microglia and infiltrating macrophages. This imbalance leads to foam cell formation in the infarct and areas of
Externí odkaz:
https://doaj.org/article/fd27e7413e1d47248acce683e0703bc8
Autor:
Sanna H Loppi, Marco A Tavera-Garcia, Danielle A Becktel, Boaz K Maiyo, Kristos E Johnson, Thuy-Vi V Nguyen, Rick G Schnellmann, Kristian P Doyle
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. :0271678X2311572
The goal of this study was to evaluate changes in metabolic homeostasis during the first 12 weeks of recovery in a distal middle cerebral artery occlusion mouse model of stroke. To achieve this goal, we compared the brain metabolomes of ipsilateral a
Autor:
Sanna H. Loppi, Marco A. Tavera-Garcia, Danielle A. Becktel, Boaz K. Maiyo, Kristos E. Johnson, Rick G. Schnellmann, Kristian P. Doyle
The goal of this study was to evaluate changes in metabolic homeostasis during the first 12 weeks of recovery in a distal middle cerebral artery occlusion mouse model of stroke. To achieve this goal, we compared the brain metabolomes of ipsilateral a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87fd8e179dc3d9bb84169760389a198a
https://doi.org/10.1101/2022.03.22.485395
https://doi.org/10.1101/2022.03.22.485395
Autor:
Kylie Calderon, Frankie G. Garcia, Helena W. Morrison, Crumpacker Rh, Danielle A. Becktel, Gonzalez S, Frank M. Longo, Marco A. Tavera-Garcia, Jennifer B. Frye, Tony T. Yang, Rick G. Schnellmann, Jacob C. Zbesko, Kristian P. Doyle, Thuy-Vi V. Nguyen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 380(2)
The aim of this study was to test whether post-stroke oral administration of a small molecule p75 neurotrophin receptor (p75NTR) modulator (LM11A-31) can augment neuronal survival and improve recovery in a mouse model of stroke. Mice were administere
Autor:
Deepta Bhattacharya, Jessica Stokes, Jacob C. Zbesko, Danielle A. Becktel, Jennifer B. Frye, Kylie Calderon, Diana K. Gerardo, Kristian P. Doyle, Thuy-Vi V. Nguyen
Publikováno v:
Brain, behavior, and immunity
Up to 30% of stroke patients experience cognitive decline within one year of their stroke. There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in part due to a poor understanding of the mechanisms involved. We ha
Autor:
Amanda G. Chung, Jennifer B. Frye, Jacob C. Zbesko, Eleni Constantopoulos, Megan Hayes, Anna G. Figueroa, Danielle A. Becktel, W. Antony Day, John P. Konhilas, Brian S. McKay, Thuy-Vi V. Nguyen, Kristian P. Doyle
Here we used mouse models of heart and brain ischemia to compare the inflammatory response to ischemia in the heart, a protein rich organ, to the inflammatory response to ischemia in the brain, a lipid rich organ. We report that ischemia-induced infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d57b4b30a7187af698986ce292252
Autor:
Jacob C. Zbesko, Anna G. Figueroa, Kristian P. Doyle, Eleni Constantopoulos, John P. Konhilas, Jennifer B. Frye, Megan Hayes, W. Antony Day, Danielle A. Becktel, Amanda Chung, Thuy-Vi V. Nguyen, Brian S. McKay
Publikováno v:
eNeuro
Here we used mouse models of heart and brain ischemia to compare the inflammatory response to ischemia in the heart, a protein rich organ, to the inflammatory response to ischemia in the brain, a lipid rich organ. We report that ischemia-induced infl