Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Danielle A Garsin"'
Autor:
Mazen Oneissi, Melissa R Cruz, Bernardo Ramírez-Zavala, Elena Lindemann-Perez, Joachim Morschhäuser, Danielle A Garsin, J Christian Perez
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011692 (2023)
The signals that denote mammalian host environments and dictate the activation of signaling pathways in human-associated microorganisms are often unknown. The transcription regulator Rtg1/3 in the human fungal pathogen Candida albicans is a crucial d
Externí odkaz:
https://doaj.org/article/3e24ff7738a7433bbed0362a16129276
Autor:
Armand O Brown, Danielle A Garsin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009021 (2020)
Externí odkaz:
https://doaj.org/article/2e652e3600614cdd872f1179d778e016
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007944 (2019)
Heme-containing peroxidases are important components of innate immunity. Many of them functionally associate with NADPH oxidase (NOX)/dual oxidase (DUOX) enzymes by using the hydrogen peroxide they generate in downstream reactions. Caenorhabditis ele
Externí odkaz:
https://doaj.org/article/49608ace9a564bdca7b9b250e4a0bf53
Autor:
Katie C McCallum, Danielle A Garsin
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005923 (2016)
Externí odkaz:
https://doaj.org/article/a4ead6400a7648e0960caa1577a85993
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124091 (2015)
Dual oxidases (DUOX) are enzymes that contain an NADPH oxidase domain that produces hydrogen peroxide (H2O2) and a peroxidase domain that can utilize H2O2 to carry out a variety of reactions. The model organism Caenorhabditis elegans produces the DUO
Externí odkaz:
https://doaj.org/article/89bd3435931b48d584669a9a20047d43
Autor:
Arati Ramesh, Sruti DebRoy, Jonathan R Goodson, Kristina A Fox, Herbey Faz, Danielle A Garsin, Wade C Winkler
Publikováno v:
PLoS Genetics, Vol 8, Iss 6, p e1002666 (2012)
ANTAR proteins are widespread bacterial regulatory proteins that have RNA-binding output domains and utilize antitermination to control gene expression at the post-initiation level. An ANTAR protein, EutV, regulates the ethanolamine-utilization genes
Externí odkaz:
https://doaj.org/article/43674c6b76f14ae382a870a27616fb14
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002453 (2011)
Infected animals will produce reactive oxygen species (ROS) and other inflammatory molecules that help fight pathogens, but can inadvertently damage host tissue. Therefore specific responses, which protect and repair against the collateral damage cau
Externí odkaz:
https://doaj.org/article/ff3e9957461646dcb8dcee81d277d5c1
Autor:
Ángela Sanzo-Machuca, José Manuel Monje Moreno, Rafael Casado-Navarro, Ozgur Karakuzu, David Guerrero-Gómez, Juan Carlos Fierro-González, Peter Swoboda, Manuel J. Muñoz, Danielle A. Garsin, José Rafael Pedrajas, Arantza Barrios, Antonio Miranda-Vizuete
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
Thioredoxins (TRX) are traditionally considered as enzymes catalyzing redox reactions. However, redox-independent functions of thioredoxins have been described in different organisms, although the underlying molecular mechanisms are yet unknown. We r
Externí odkaz:
https://doaj.org/article/d6afa2f126bd48da8c460e932d8047cf
Autor:
Melissa R. Cruz, Shane Cristy, Shantanu Guha, Giuseppe Buda De Cesare, Elena Evdokimova, Hiram Sanchez, Dominika Borek, Pedro Miramón, Junko Yano, Paul L. Fidel, Alexei Savchenko, David R. Andes, Peter J. Stogios, Michael C. Lorenz, Danielle A. Garsin
Publikováno v:
Nature Communications. 13
Fungal pathogens are a continuing challenge due to few effective antifungals and a rise in resistance. In previous work, we described the inhibition of Candida albicans virulence following exposure to the 68 amino acid bacteriocin, EntV, secreted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedb15cdb33ab3829e77703bbb4efdd2
https://doi.org/10.1038/s41467-022-33613-1
https://doi.org/10.1038/s41467-022-33613-1
Autor:
Karan Gautam Kaval, Barbara E. Murray, Armand O. Brown, Liezl E. Francisco, Kavindra V. Singh, Danielle A. Garsin, Melissa R. Cruz
Publikováno v:
J Infect Dis
Enterococcus faecalis is a significant cause of hospital-acquired bacteremia. Herein, the discovery is reported that cardiac microlesions form during severe bacteremic E. faecalis infection in mice. The cardiac microlesions were identical in appearan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9c45a49dc44cea474627382df514fb
https://doi.org/10.1093/infdis/jiaa371
https://doi.org/10.1093/infdis/jiaa371