Clinical criteria replenish high-sensitive troponin and inflammatory markers in the stratification of patients with suspected acute coronary syndrome.

Autor: Barbara Elisabeth Stähli, Keiko Yonekawa, Lukas Andreas Altwegg, Christophe Wyss, Danielle Hof, Philipp Fischbacher, Andreas Brauchlin, Georg Schulthess, Pierre-Alexandre Krayenbühl, Arnold von Eckardstein, Martin Hersberger, Michel Neidhart, Steffen Gay, Igor Novopashenny, Regine Wolters, Michelle Frank, Manfred Bernd Wischnewsky, Thomas Felix Lüscher, Willibald Maier

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98626 (2014)

OBJECTIVES: In patients with suspected acute coronary syndrome (ACS), rapid triage is essential. The aim of this study was to establish a tool for risk prediction of 30-day cardiac events (CE) on admission. 30-day cardiac events (CE) were defined as

Externí odkaz: https://doaj.org/article/7ba48aa903e44b10ae7263331fecfa94

Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis.

Autor: Seraina Cooksley-Decasper, Hans Reiser, Daniela S Thommen, Barbara Biedermann, Michel Neidhart, Joanna Gawinecka, Gieri Cathomas, Fabian C Franzeck, Christophe Wyss, Roland Klingenberg, Paolo Nanni, Bernd Roschitzki, Christian Matter, Petra Wolint, Maximilian Y Emmert, Marc Husmann, Beatrice Amann-Vesti, Wilibald Maier, Steffen Gay, Thomas F Lüscher, Arnold von Eckardstein, Danielle Hof

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47985 (2012)

To date, no plaque-derived blood biomarker is available to allow diagnosis, prognosis or monitoring of atherosclerotic vascular diseases. In this study, specimens of thrombendarterectomy material from carotid and iliac arteries were incubated in prot

Externí odkaz: https://doaj.org/article/bb51be72e980485c9302e17808f891b8

High-Sensitivity Troponin Assays in Clinical Diagnostics of Acute Coronary Syndrome

Autor: Danielle Hof, Arnold von Eckardstein

Publikováno v: Methods in Molecular Biology ISBN: 9781493990290

Nowadays, measurement of cardiac troponins (cTn) in patient plasma is central for diagnosis of patients with acute coronary syndrome (ACS). High-sensitivity (hs) immunoassays have been developed that can very precisely record slightly elevated and ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb574730a479cdc6d16bb2b920ab2cd
https://doi.org/10.1007/978-1-4939-9030-6_40

High-sensitivity Troponins—Difficult Friends in Acute Coronary Syndromes

Autor: Roland Klingenberg, Christian M Matter, Christophe Wyss, Danielle Hof, Arnold von Eckardstein, Thomas F Lüscher

Publikováno v: Winter. 9:121-125

The introduction of novel high-sensitivity cardiac troponin (hs-cTn) assays has made it possible to measure cardiac troponin levels that are up to 10-fold lower than those detectable by conventional cardiac troponin (cTn) assays. With such novel assa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ff53ed9105b5f1e21fd7cb04a93abac
https://doi.org/10.15420/usc.2012.9.2.121

Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals

Autor: Nicolas Rodondi, Peter Vollenweider, Helena Marti Soler, Danielle Hof, Alexander Akhmedov, Dik Heg, Arnold von Eckardstein, Pedro Marques-Vidal, Ulf Landmesser, Thomas F. Lüscher, Stefan Zoller, Joanna Gawinecka, Stephan Windecker, Roland Klingenberg, Nina Fuchs, François Mach, Seraina Cooksley-Decasper, Christian M. Matter, Hans Reiser

Publikováno v: Reiser, Hans; Klingenberg, Roland; Hof, Danielle; Cooksley-Decasper, Seraina; Fuchs, Nina; Akhmedov, Alexander; Zoller, Stefan; Marques-Vidal, Pedro; Marti Soler, Helena; Heg, Dik; Landmesser, Ulf; Rodondi, Nicolas; Mach, Francois; Windecker, Stephan; Vollenweider, Peter; Matter, Christian M; Lüscher, Thomas F; von Eckardstein, Arnold; Gawinecka, Joanna (2015). Circulating FABP4 Is a Prognostic Biomarker in Patients With Acute Coronary Syndrome but Not in Asymptomatic Individuals. Arteriosclerosis, thrombosis, and vascular biology, 35(8), pp. 1872-1879. Lippincott Williams & Wilkins 10.1161/ATVBAHA.115.305365
Arteriosclerosis thrombosis and vascular biology
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Objective— Blood-borne biomarkers reflecting atherosclerotic plaque burden have great potential to improve clinical management of atherosclerotic coronary artery disease and acute coronary syndrome (ACS). Approach and Results— Using data integrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07406fb39c09d20f088c03869ab1ceaa
https://doi.org/10.5167/uzh-111377