Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Danielle, Falcone"'
Publikováno v:
Journal of Student Research. 9
This study analyzed the Chromium (VI) levels present in three Arizona counties tap water, as represented by the major universities residing within them. Each sample was surveyed using spectrophotometry to determine the contaminant levels of Cr(VI) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d7601b64e6183e3093f5541516bd64
https://doi.org/10.47611/jsr.v9i1.815
https://doi.org/10.47611/jsr.v9i1.815
Autor:
Michael D. Altman, Christopher J. Dinsmore, John F. Reilly, Jonathan R. Young, Chaomin Li, Sangita B. Patel, Deborah Walker, Craig Rosenstein, David Joseph Guerin, Timothy Allison, Harold Hatch, Stephen M. Soisson, Sujal V. Deshmukh, Bart Lutterbach, Bo Sheng Pan, Danielle Falcone, Michael H. Reutershan, Keith W. Rickert, Matthew H. Katcher, Wei Lu, Melissa Chenard, Kevin J. Wilson, Alan B. Northrup, Alexander A. Szewczak, Matthew H. Daniels
Publikováno v:
Journal of Medicinal Chemistry. 56:2294-2310
This report documents the first example of a specific inhibitor of protein kinases with preferential binding to the activated kinase conformation: 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one 11r (MK-8033), a dual c-Met/Ron inhibitor under investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1117137a3ef810ac7f93b40f98ec667e
https://doi.org/10.1021/jm301619u
https://doi.org/10.1021/jm301619u
Autor:
Jason D. Katz, Bart Lutterbach, Harold Hatch, Robert J. Mathvink, Wenxian Wang, Xianlu Qu, Kaiko Kunii, C. Gary Marshall, Bo-Sheng Pan, Keith W. Rickert, Craig Rosenstein, Alexander A. Szewczak, Jonathan R. Young, Kevin J. Lumb, David Joseph Guerin, Sangita B. Patel, Gaozhen Hang, Qinwen Zeng, Sujal V. Deshmukh, Deborah Walker, Danielle Falcone, Stephen M. Soisson, Lenora Davis, Rachael Holmes, Kerrie Spencer, William K. Dahlberg, Wei Lu, James P. Jewell, Ana Esther Ortega Gabarda, Naim Nazef, Michael D. Altman, Christopher J. Dinsmore, John F. Reilly, Jongwon Lim
Publikováno v:
Journal of Medicinal Chemistry. 54:4092-4108
c-Met is a transmembrane tyrosine kinase that mediates activation of several signaling pathways implicated in aggressive cancer phenotypes. In recent years, research into this area has highlighted c-Met as an attractive cancer drug target, triggering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bb91af3692bfd588518c6f2783785f
https://doi.org/10.1021/jm200112k
https://doi.org/10.1021/jm200112k
Publikováno v:
Tetrahedron Letters. 55:2646-2648
A synthesis of N-aryl and N-heteroaryl amino acid derivatives using palladium catalysis is described. Several carbamate-protected glycine derivatives react with aryl and heteroaryl halides using a palladium/Xantphos catalyst system to access the desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c87bb5df89af399429e1c21b81a09b
https://doi.org/10.1016/j.tetlet.2014.03.016
https://doi.org/10.1016/j.tetlet.2014.03.016
Autor:
Coleen Holewa, Graham B. Jones, Amy E. Kallmerten, Paul J. LaBeaume, Danielle Falcone, Krista M. Wager, Jane Li, Vladimir P. Torchilin, Curtis Castro
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:6292-6300
Methodology is outlined for the chemical synthesis of versatile photo-Bergman enediyne building blocks and their conjugates. Routes to both mono and bis conjugated enediyne templates are detailed together with representative examples of their bioconj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1bee8c49b91f7a7d6035dcee61a155
https://doi.org/10.1016/j.bmc.2009.07.059
https://doi.org/10.1016/j.bmc.2009.07.059
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:934-937
Efficient syntheses of a series of functionalized aryl enediynes have been developed. The building blocks were used to effect conjugation to carrier PEG templates which allowed subsequent coupling to a cardiac targeted monoclonal antibody. Immunocomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe879081a2532e1d3d9140eae030f2b
https://doi.org/10.1016/j.bmcl.2007.12.045
https://doi.org/10.1016/j.bmcl.2007.12.045
Publikováno v:
ChemInform. 45
A synthesis of N-aryl and N-heteroaryl amino acid derivatives using palladium catalysis is described. Several carbamate-protected glycine derivatives react with aryl and heteroaryl halides using a palladium/Xantphos catalyst system to access the desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b950e9cb2eb471c5c5402295268664f0
https://doi.org/10.1002/chin.201440050
https://doi.org/10.1002/chin.201440050
Publikováno v:
Journal of Chemical Education. 87:84-86
Microwave heating enhanced the rate of three reactions typically performed in our undergraduate organic chemistry laboratory: a Diels−Alder cycloaddition, a Wittig salt formation, and a Williamson ether synthesis. Ninety-minute refluxes were shorte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1cdcb879d3804a8ba18e7fc72df798c
https://doi.org/10.1021/ed800001x
https://doi.org/10.1021/ed800001x
Autor:
Alan B, Northrup, Matthew H, Katcher, Michael D, Altman, Melissa, Chenard, Matthew H, Daniels, Sujal V, Deshmukh, Danielle, Falcone, David J, Guerin, Harold, Hatch, Chaomin, Li, Wei, Lu, Bart, Lutterbach, Timothy J, Allison, Sangita B, Patel, John F, Reilly, Michael, Reutershan, Keith W, Rickert, Craig, Rosenstein, Stephen M, Soisson, Alexander A, Szewczak, Deborah, Walker, Kevin, Wilson, Jonathan R, Young, Bo-Sheng, Pan, Christopher J, Dinsmore
Publikováno v:
Journal of medicinal chemistry. 56(6)
This report documents the first example of a specific inhibitor of protein kinases with preferential binding to the activated kinase conformation: 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one 11r (MK-8033), a dual c-Met/Ron inhibitor under investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4116662dcbbe55aab9b82313c0024c89
https://pubmed.ncbi.nlm.nih.gov/23379595
https://pubmed.ncbi.nlm.nih.gov/23379595