Výsledky vyhledávání - "Danielle, Carpenter"

Akademický článek

Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo

Autor: Sandip Mukherjee, Molee Chakraborty, Eliwaza N. Msengi, Jake Haubner, Jinsong Zhang, Matthew J. Jellinek, Haley L. Carlson, Kelly Pyles, Barbara Ulmasov, Andrew J. Lutkewitte, Danielle Carpenter, Kyle S. McCommis, David A. Ford, Brian N. Finck, Brent A. Neuschwander-Tetri, Anutosh Chakraborty

Publikováno v: Molecular Metabolism, Vol 75, Iss , Pp 101767- (2023)

Objective: Defining the regulators of cell metabolism and signaling is essential to design new therapeutic strategies in obesity and NAFLD/NASH. E3 ubiquitin ligases control diverse cellular functions by ubiquitination-mediated regulation of protein

Externí odkaz: https://doaj.org/article/b2642d46704a4c24822cb884661aab61

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Akademický článek

The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling

Autor: Sandip Mukherjee, Molee Chakraborty, Jake Haubner, Glen Ernst, Michael DePasquale, Danielle Carpenter, James C. Barrow, Anutosh Chakraborty

Publikováno v: Biomolecules, Vol 13, Iss 5, p 868 (2023)

Obesity and nonalcoholic fatty liver disease (NAFLD) are global health concerns, and thus, drugs for the long-term treatment of these diseases are urgently needed. We previously discovered that the inositol pyrophosphate biosynthetic enzyme IP6K1 is

Externí odkaz: https://doaj.org/article/2695fa91a3a24772ab51b42c8d89cc7f

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Akademický článek

ENhAncing Lifestyle Behaviors in EndometriaL CancEr (ENABLE): A Pilot Randomized Controlled Trial

Autor: Lara Edbrooke PhD, Pearly Khaw MBBS, FRANZCR, Alison Freimund MBBS, Danielle Carpenter MANP, Orla McNally MB BAO BCh, FRANZCOG, Lynette Joubert PhD, Jenelle Loeliger MND, AdvADP, Anya Traill MPH, Karla Gough PhD, Linda Mileshkin MBBS, FRACP, Linda Denehy PhD

Publikováno v: Integrative Cancer Therapies, Vol 21 (2022)

Purpose: Endometrial cancer is associated with the highest comorbid disease burden of any cancer. The aim of this trial was to assess the feasibility and safety of an allied health intervention during adjuvant treatment. Methods: A mixed-methods pilo

Externí odkaz: https://doaj.org/article/770a512ada894347b91ee3f69abb9486

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Akademický článek

Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis

Autor: Sandip Mukherjee, Molee Chakraborty, Barbara Ulmasov, Kyle McCommis, Jinsong Zhang, Danielle Carpenter, Eliwaza Naomi Msengi, Jake Haubner, Chun Guo, Daniel P. Pike, Sarbani Ghoshal, David A. Ford, Brent A. Neuschwander-Tetri, Anutosh Chakraborty

Publikováno v: Molecular Metabolism, Vol 54, Iss , Pp 101364- (2021)

Objective: Obesity and insulin resistance greatly increase the risk of nonalcoholic fatty liver disease and steatohepatitis (NAFLD/NASH). We have previously discovered that whole-body and adipocyte-specific Ip6k1deletion protects mice from high-fat-d

Externí odkaz: https://doaj.org/article/fd13f5e8e9714681819f553c2658c06f

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Akademický článek

A Rare Case of Pancreatic Endometriosis Masquerading as Pancreatic Mucinous Neoplasm

Autor: Barton Huang, Annie Mooser, Danielle Carpenter, Grace Montenegro, Carrie Luu

Publikováno v: Case Reports in Surgery, Vol 2021 (2021)

Endometriosis is a relatively common condition among women, and pancreatic endometriosis has been reported on rare occasions. Such pancreatic lesions are difficult to diagnose and distinguish from other cystic lesions of the pancreas preoperatively.

Externí odkaz: https://doaj.org/article/517419a7bf9146cab66e3fd1fd511edc

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