Výsledky vyhledávání - "Daniella Vaskovich"

Akademický článek

Intranasal Multiepitope PD‐L1‐siRNA‐Based Nanovaccine: The Next‐Gen COVID‐19 Immunotherapy

Publikováno v: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)

Abstract The first approved vaccines for human use against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are nanotechnology‐based. Although they are modular, rapidly produced, and can reduce disease severity, the currently availa

Externí odkaz: https://doaj.org/article/b5734eacdf3b49c7be9c99d042cb5913

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Abstract 3243: Modulating the brain immune system to fight cancer in 3 dimensions

Autor: Eilam Yeini, Daniella Vaskovich-Koubi, Ron Kleiner, Helena F. Florindo, Ronit Satchi-Fainaro

Publikováno v: Cancer Research. 83:3243-3243

Despite the remarkable efficiency of immune checkpoint modulators against primary and metastatic brain neoplasms, there is a low percentage of responders and clinical trials report severe immune-mediated side effects and disease relapse. An accumulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::911421bebbc46c4777c09cdb56480c42
https://doi.org/10.1158/1538-7445.am2023-3243

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Preclinical models and technologies to advance nanovaccine development

Autor: Rita C. Acúrcio, Helena F. Florindo, Carina Peres, Barbara Carreira, Daniella Vaskovich-Koubi, Sabina Pozzi, Ronit Satchi-Fainaro, Ana I. Matos, Liane I.F. Moura, Ron Kleiner

Publikováno v: Advanced drug delivery reviews. 172

The remarkable success of targeted immunotherapies is revolutionizing cancer treatment. However, tumor heterogeneity and low immunogenicity, in addition to several tumor-associated immunosuppression mechanisms are among the major factors that have pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8881d13a21f0b23da1bc31fc623e27b1
https://pubmed.ncbi.nlm.nih.gov/33711401

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Abstract 3520: Designing a dendritic cell-targeted immunotherapy for the treatment of pancreatic ductal adenocarcinoma

Autor: Daniella Vaskovich-Koubi, Ron kleiner, Anat Eldar-Boock, Sabina Pozzi, Dikla Dikla Ben-Shushan, Helena F. Florindo, Ronit Satchi-Fainaro

Publikováno v: Cancer Research. 82:3520-3520

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death. Low response rate, acquired resistance, severe side effects, highly desmoplastic, and immunosuppressive microenvironment have limited the clinical outcomes o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a6de71740747717297e6318d9c08f8e
https://doi.org/10.1158/1538-7445.am2022-3520

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Abstract 1746: Designing a dendritic cell-targeted immunotherapy for the treatment of pancreatic ductal adenocarcinoma

Autor: Helena F. Florindo, Ronit Satchi-Fainaro, Anat Eldar-Boock, Dikla Ben-Shushan, Sabina Pozzi, Ron Kleiner, Daniella Vaskovich

Publikováno v: Cancer Research. 81:1746-1746

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death. Low response rate, acquired resistance, severe side effects, highly desmoplastic and immunosuppressive microenvironment have limited the clinical outcomes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b67c91d4401bc3838855bed1873f0c0
https://doi.org/10.1158/1538-7445.am2021-1746

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Abstract 714: From cancer to COVID-19- development of a dendritic cell-targeted nano-vaccine for prevention and therapy of COVID-19

Autor: Ron Kleiner, Daniella Vaskovich-Koubi, Anat Eldar-Boock, Helena F. Florindo, Eilam Yeini, Yulia Liubomirski, Sabina Pozzi, Galia Tiram, Ronit Satchi-Fainaro

Publikováno v: Cancer Research. 81:714-714

Dendritic cells (DC) are antigen-presenting cells with an important role in the initiation and regulation of the innate and adaptive arms of the immune system. By efficient presentation of antigens, DC elicit an antigen-specific immune response. Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::836a86b7a7135e0e30cfe26e253b1eaf
https://doi.org/10.1158/1538-7445.am2021-714

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Immune-mediated approaches against COVID-19

Autor: Barbara Carreira, Helena F. Florindo, Ronit Satchi-Fainaro, Ron Kleiner, Yulia Liubomirski, Galia Tiram, Rita C. Acúrcio, Daniella Vaskovich-Koubi, Eilam Yeini

Publikováno v: Nature Nanotechnology

The coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The long incubation period of this new virus, which is mostly asymptomatic yet contagious, is a key reason for its rapid spread acros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1b66bd3118f27d78c31d1818c40c48

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Meet me halfway: Are in vitro 3D cancer models on the way to replace in vivo models for nanomedicine development?

Autor: Lena Neufeld, Ron Kleiner, Shani Koshrovski-Michael, Noa Reisman, Paula Ofek, Sahar Israeli Dangoor, Pradip Dey, Anna Scomparin, Ronit Satchi-Fainaro, Adva Krivitsky, Sabina Pozzi, Daniella Vaskovich-Koubi, Daniel Rodriguez Ajamil

Publikováno v: Advanced Drug Delivery Reviews

The complexity and diversity of the biochemical processes that occur during tumorigenesis and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two-dimensional cultures limit researchers’ experimental observations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2124f744585855c53a6025004f90886c

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