The VALTIVE1 study protocol: a study for the validation of Tie2 as the first tumour vascular response biomarker for VEGF inhibitors

Autor: Margherita Carucci, Andrew Clamp, Cong Zhou, Chris Hurt, Rosalind Glasspool, Phillip J. Monaghan, Sally Thirkettle, Michael Wheatley, Madia Mahmood, Monica Narasimham, Tracy Cox, Hilary Morrison, Susan Campbell, Annmarie Nelson, Daniella Holland-Hart, Noreen Hopewell-Kelly, Abin Thomas, Catharine Porter, Magdalena Slusarczyk, Alys Irving, Caroline Dive, Richard Adams, Gordon C. Jayson

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)

Abstract Background Anti-angiogenic, VEGF inhibitors (VEGFi) increase progression-free survival (PFS) and, in some cases, overall survival in many solid tumours. However, their use has been compromised by a lack of informative biomarkers. We have sho

Externí odkaz: https://doaj.org/article/2cb2b6eb4c584bf9a3d37059d285edbd

Understanding how shared decision‐making approaches and patient aids influence patients with advanced cancer when deciding on palliative treatments and care: A realist review

Autor: Michelle Edwards, Daniella Holland‐Hart, Mala Mann, Kathy Seddon, Peter Buckle, Mirella Longo, Anthony Byrne, Annmarie Nelson

Publikováno v: Health Expectations, Vol 26, Iss 6, Pp 2109-2126 (2023)

Abstract Background Patients with advanced incurable cancer face difficult decisions about palliative treatment options towards their end of life. However, they are often not provided with the appropriate information and support that is needed to mak

Externí odkaz: https://doaj.org/article/48c4e2e00c3841048ee65badad73ff33

Feasibility and acceptability of a community pharmacy referral service for suspected lung cancer symptoms

Autor: Kate Brain, Harriet Dorothy Quinn-Scoggins, Angela Evans, Grace M McCutchan, Rachel Gemine, Kelly White, Sarah Bowen, Lucy Hill, Daniella Holland-Hart, Savita Shanbag, Michael Abel, Sarah Rees, Gareth Collier

Publikováno v: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)

Background Lung cancer survival rates in the UK are among the lowest in Europe, principally due to late-stage diagnosis. Alternative routes to earlier diagnosis of lung cancer are needed in socioeconomically deprived communities that are disproportio

Externí odkaz: https://doaj.org/article/ae6a0dab118746828f98ba6f184a3efc

Developing decision support tools incorporating personalised predictions of likely visual benefit versus harm for cataract surgery:research programme

Autor: John M Sparrow, Mariusz Grzeda, Andrew Frost, Christopher Liu, Robert L Johnston, Peter Scanlon, Christalla Pithara, Daisy Elliott, Jenny Donovan, Natalie Joseph-Williams, Daniella Holland-Hart, Paul HJ Donachie, Padraig Dixon, Rebecca Kandiyali, Hazel Taylor, Katie Breheny, Jonathan Sterne, William Hollingworth, David Evans, Fiona Fox, Sofia Theodoropoulou, Rachael Hughes, Matthew Quinn, Daniel Gray, Larry Benjamin, Abi Loose, Lara Edwards, Pippa Craggs, Frances Paget, Ketan Kapoor, Jason Searle

Publikováno v: Sparrow, J M, Grzeda, M T, Frost, A, Liu, C, Johnston, R L, Scanlon, P, Pithara-McKeown, C, Elliott, D, Donovan, J L, Joseph-Williams, N, Holland-Hart, D, Donachie, P HJ, Dixon, P C, Kandiyali, R, Taylor, H, Breheny, K, Sterne, J A C, Hollingworth, W, Evans, D, Fox, F E, Theodoropoulou, S, Hughes, R, Quinn, M, Gray, D, Benjamin, L, Loose, A, Edwards, L, Craggs, P, Paget, F V, Kapoor, K & Searle, J 2022, ' Developing decision support tools incorporating personalised predictions of likely visual benefit versus harm for cataract surgery : research programme ', NIHR Open Research, vol. 10, no. 9 . https://doi.org/10.3310/BAGA4188

Background Surgery for established cataract is highly cost-effective and uncontroversial, yet uncertainty remains for individuals about when to proceed and when to delay surgery during the earlier stages of cataract. Objective We aimed to improve dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f861f46c2f572ac4d5ef5b6b2fa6f66
https://research-information.bris.ac.uk/en/publications/36d293ad-5938-415d-b0e8-793208d64dc3

Feasibility and acceptability of a community pharmacy referral service for suspected lung cancer symptoms

Autor: Lucy Hill, Gareth Collier, Katherine Emma Brain, Michael Abel, Sarah Bowen, Sarah Rees, Grace McCutchan, Savita Shanbag, Rachel Gemine, Angela Evans, Kelly White, Harriet Quinn-Scoggins, Daniella Holland-Hart

Publikováno v: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
BMJ Open Respiratory Research

BackgroundLung cancer survival rates in the UK are among the lowest in Europe, principally due to late-stage diagnosis. Alternative routes to earlier diagnosis of lung cancer are needed in socioeconomically deprived communities that are disproportion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627efc48ccd72d6586de03d9824a2b10
https://doi.org/10.1136/bmjresp-2020-000772