Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daniella C. Bartholomeu"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-6 (2024)
Abstract Background Gene families are groups of homologous genes that often have similar biological functions. These families are formed by gene duplication events throughout evolution, resulting in multiple copies of an ancestral gene. Over time, th
Externí odkaz:
https://doaj.org/article/2943ce5ea26646df9cd39ecf55935048
Autor:
João Luís Reis-Cunha, Anderson Coqueiro-dos-Santos, Samuel Alexandre Pimenta-Carvalho, Larissa Pinheiro Marques, Gabriela F. Rodrigues-Luiz, Rodrigo P. Baptista, Laila Viana de Almeida, Nathan Ravi Medeiros Honorato, Francisco Pereira Lobo, Vanessa Gomes Fraga, Lucia Maria da Cunha Galvão, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Mariana Santos Cardoso, Gustavo Coutinho Cerqueira, Daniella C. Bartholomeu
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Repetitive elements cause assembly fragmentation in complex eukaryotic genomes, limiting the study of their variability. The genome of Trypanosoma cruzi, the parasite that causes Chagas disease, has a high repetitive content, including multi
Externí odkaz:
https://doaj.org/article/ba5075b9a21e493ead3788e470e0b902
Autor:
Hugo O. Valdivia, Bruno M. Roatt, Rodrigo de Paula Baptista, Jennifer Ottino, Anderson Coqueiro-dos-Santos, Mandy J. Sanders, Alexandre B. Reis, James A. Cotton, Daniella C. Bartholomeu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Visceral leishmaniasis is an important global health problem with an estimated of 50,000 to 90,000 new cases per year. VL is the most serious form of leishmaniasis as it can be fatal in 95% of the cases if it remains untreated. VL is a particularly a
Externí odkaz:
https://doaj.org/article/0c34e21bff514f769362c18087968f16
Autor:
Rohit Sharma, Francys Avendaño Rangel, João Luís Reis-Cunha, Larissa Pinheiro Marques, Claudio P. Figueira, Pedro B. Borba, Sayonara M. Viana, Tom Beneke, Daniella C. Bartholomeu, Camila I. de Oliveira
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Leishmania braziliensis is the main causative agent of Tegumentary Leishmaniasis in the Americas. However, difficulties related to genome manipulation, experimental infection, and parasite growth have so far limited studies with this species. CRISPR-
Externí odkaz:
https://doaj.org/article/8a1885cefb254ad9a2caa9b9b29cff7e
Autor:
Gabriela de A. Burle-Caldas, Nailma S. A. dos Santos, Júlia T. de Castro, Fernanda L. B. Mugge, Viviane Grazielle-Silva, Antônio Edson R. Oliveira, Milton C. A. Pereira, João Luís Reis-Cunha, Anderson Coqueiro dos Santos, Dawidson Assis Gomes, Daniella C. Bartholomeu, Nilmar S. Moretti, Sergio Schenkman, Ricardo T. Gazzinelli, Santuza M. R. Teixeira
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Trans-sialidases (TS) are unusual enzymes present on the surface of Trypanosoma cruzi, the causative agent of Chagas disease. Encoded by the largest gene family in the T. cruzi genome, only few members of the TS family have catalytic activit
Externí odkaz:
https://doaj.org/article/726ccde2ca8642a08b521362024bc308
Autor:
Carlos Talavera-López, Louisa A. Messenger, Michael D. Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos, Daniella C. Bartholomeu, José E. Calzada, Azael Saldaña, Juan David Ramírez, Felipe Guhl, Sofía Ocaña-Mayorga, Jaime A. Costales, Rodion Gorchakov, Kathryn Jones, Melissa S. Nolan, Santuza M. R. Teixeira, Hernán José Carrasco, Maria Elena Bottazzi, Peter J. Hotez, Kristy O. Murray, Mario J. Grijalva, Barbara Burleigh, Edmundo C. Grisard, Michael A. Miles, Björn Andersson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Trypanosoma cruzi, a zoonotic kinetoplastid protozoan parasite, is the causative agent of American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex genome, the parasite displays a highly diverse repertoire of surface mo
Externí odkaz:
https://doaj.org/article/a4cd59512a324280b349602a5bf83648
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 116 (2021)
The availability of Trypanosomatid genomic data in public databases has opened myriad experimental possibilities that have contributed to a more comprehensive understanding of the biology of these parasites and their interactions with hosts. In this
Externí odkaz:
https://doaj.org/article/5a510d315289437baad56c83600de748
Autor:
Anthony F. La Marca, Robson da S. Lopes, Anna Diva P. Lotufo, Daniella C. Bartholomeu, Carlos R. Minussi
Publikováno v:
Sensors, Vol 22, Iss 11, p 4027 (2022)
The public health system is extremely dependent on the use of vaccines to immunize the population from a series of infectious and dangerous diseases, preventing the system from collapsing and millions of people dying every year. However, to develop t
Externí odkaz:
https://doaj.org/article/72ab7f6cbf5844fb9e93d7012cc179b9
Autor:
João Luís Reis-Cunha, Rodrigo P. Baptista, Gabriela F. Rodrigues-Luiz, Anderson Coqueiro-dos-Santos, Hugo O. Valdivia, Laila Viana de Almeida, Mariana Santos Cardoso, Daniella Alchaar D’Ávila, Fernando Hugo Cunha Dias, Ricardo Toshio Fujiwara, Lúcia M. C. Galvão, Egler Chiari, Gustavo Coutinho Cerqueira, Daniella C. Bartholomeu
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled in human infections in South America southern cone, where
Externí odkaz:
https://doaj.org/article/9e19a2b6cd2b4c9fa08073b8d70d1199
Autor:
Anna Paula V. Moura, Luiza C. B. Santos, Carlos Ramon Nascimento Brito, Edward Valencia, Caroline Junqueira, Adalberto A. P. Filho, Mauricio R. V. Sant’Anna, Nelder F. Gontijo, Daniella C. Bartholomeu, Ricardo T. Fujiwara, Ricardo T. Gazzinelli, Craig S. McKay, Carlos A. Sanhueza, M. G. Finn, Alexandre Ferreira Marques
Publikováno v:
ACS Central Science, Vol 3, Iss 9, Pp 1026-1031 (2017)
Externí odkaz:
https://doaj.org/article/627498c0687c46b1aaa84a76965ff7d2