Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Daniele Zacchetti"'
Autor:
Valeria Ruggiero, Claudio Fagioli, Stefano de Pretis, Valerio Di Carlo, Nicoletta Landsberger, Daniele Zacchetti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
CDKL5 is a kinase with relevant functions in correct neuronal development and in the shaping of synapses. A decrease in its expression or activity leads to a severe neurodevelopmental condition known as CDKL5 deficiency disorder (CDD). CDD arises fro
Externí odkaz:
https://doaj.org/article/3561e301f749442799dc30d47326ef82
Autor:
Luigi Pannone, Giuseppe D’Angelo, Simone Gulletta, Giulio Falasconi, Luigia Brugliera, Antonio Frontera, Lorenzo Cianfanelli, Luca Baldetti, Paolo Ossola, Francesco Melillo, Gabriele De Blasi, Lorenzo Malatino, Giovanni Landoni, Alberto Margonato, Paolo Della Bella, Daniele Zacchetti, Pasquale Vergara
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 22, Iss 4, Pp 1383-1392 (2021)
Ventricular arrhythmias still represent an important cause of morbidity and mortality, especially in patients with heart failure and reduced left ventricular ejection fraction. Amiodarone is a Class III Vaughan-Williams anti-arrhythmic drug widely us
Externí odkaz:
https://doaj.org/article/562b0f1cd0e440fb933fccef5a88547a
Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
Autor:
Barbara Bettegazzi, Laura Sebastian Monasor, Serena Bellani, Franca Codazzi, Lisa Michelle Restelli, Alessio Vittorio Colombo, Nikolaus Deigendesch, Stephan Frank, Takashi Saito, Takaomi C. Saido, Sven Lammich, Sabina Tahirovic, Fabio Grohovaz, Daniele Zacchetti
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder. Increased Aβ production plays a fundamental role in the pathogenesis of the disease and BACE1, the protease that triggers the amyloidogenic processing of
Externí odkaz:
https://doaj.org/article/0432a5c706c549658e2f87056cfe8f8a
Redox and Calcium Alterations of a Müller Cell Line Exposed to Diabetic Retinopathy-Like Environment
Autor:
Clarissa Rosato, Barbara Bettegazzi, Pia Intagliata, Maria Balbontin Arenas, Daniele Zacchetti, Antonella Lanati, Gianpaolo Zerbini, Francesco Bandello, Fabio Grohovaz, Franca Codazzi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Diabetic retinopathy (DR) is a common complication of diabetes mellitus and is the major cause of vision loss in the working-age population. Although DR is traditionally considered a microvascular disease, an increasing body of evidence suggests that
Externí odkaz:
https://doaj.org/article/60513f111b0549baa91f9d2714d2824b
Autor:
Enrico Ragni, Carlotta Perucca Orfei, Paola De Luca, Gaia Lugano, Marco Viganò, Alessandra Colombini, Federico Valli, Daniele Zacchetti, Valentina Bollati, Laura de Girolamo
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has
Externí odkaz:
https://doaj.org/article/b1d96d527ba84dc9a1e33066425b8329
Autor:
Pasquale Vergara, Daniele Zacchetti, Paolo Della Bella, Alberto Margonato, Giovanni Landoni, Lorenzo Malatino, Gabriele De Blasi, Francesco Melillo, Paolo Ossola, Luca Baldetti, Lorenzo Cianfanelli, Antonio Frontera, Luigia Brugliera, Giulio Falasconi, Simone Gulletta, Giuseppe D’Angelo, Luigi Pannone
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 22, Iss 4, Pp 1383-1392 (2021)
Ventricular arrhythmias still represent an important cause of morbidity and mortality, especially in patients with heart failure and reduced left ventricular ejection fraction. Amiodarone is a Class III Vaughan-Williams anti-arrhythmic drug widely us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7179a5d14656e370ef24b1c142a447aa
https://rcm.imrpress.com/EN/10.31083/j.rcm2204143
https://rcm.imrpress.com/EN/10.31083/j.rcm2204143
Autor:
Federica Esposito, Ana Maria Osiceanu, Melissa Sorosina, Linda Ottoboni, Bryan Bollman, Silvia Santoro, Barbara Bettegazzi, Andrea Zauli, Ferdinando Clarelli, Elisabetta Mascia, Andrea Calabria, Daniele Zacchetti, Ruggero Capra, Maurizio Ferrari, Paolo Provero, Dejan Lazarevic, Davide Cittaro, Paola Carrera, Nikolaos Patsopoulos, Daniela Toniolo, A Dessa Sadovnick, Gianvito Martino, Philip L. De Jager, Giancarlo Comi, Elia Stupka, Carles Vilariño-Güell, Laura Piccio, Filippo Martinelli Boneschi
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2392
While the role of common genetic variants in multiple sclerosis (MS) has been elucidated in large genome-wide association studies, the contribution of rare variants to the disease remains unclear. Herein, a whole-genome sequencing study in four affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15901d8cafef06cb787e422ef5d9a23
Autor:
Michele Simonato, Franca Codazzi, Flavia Valtorta, Serena Bellani, Daniele Zacchetti, Paolo Roncon, Fabio Grohovaz, Alice Bertero, Fabrizia C. Guarnieri, Barbara Bettegazzi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Neuronal physiology requires activity-driven protein translation, a process in which translation initiation factors are key players. We focus on eukaryotic initiation factor 4B (eIF4B), a regulator of protein translation, whose function in neurons is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9ff66dd63a0df3d6a26e6e2ebafb27
http://link.springer.com/article/10.1038/s41598-017-11096-1
http://link.springer.com/article/10.1038/s41598-017-11096-1
Autor:
Barbara, Bettegazzi, Ilaria, Pelizzoni, Floramarida, Salerno Scarzella, Lisa Michelle, Restelli, Daniele, Zacchetti, Francesca, Maltecca, Giorgio, Casari, Fabio, Grohovaz, Franca, Codazzi
Publikováno v:
Oxidative Medicine and Cellular Longevity
Several neurodegenerative disorders exhibit selective vulnerability, with subsets of neurons more affected than others, possibly because of the high expression of an altered gene or the presence of particular features that make them more susceptible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de6764d2675c68497ddc0a59d663b8e0
https://pubmed.ncbi.nlm.nih.gov/31781336
https://pubmed.ncbi.nlm.nih.gov/31781336
Autor:
Carlotta Perucca Orfei, Laura de Girolamo, Valentina Bollati, Paola De Luca, Federico Valli, Gaia Lugano, Alessandra Colombini, Daniele Zacchetti, Marco Viganò, Enrico Ragni
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Background Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2f8655ce59f4eb001fd60e6347a8b6
http://europepmc.org/articles/PMC6440078
http://europepmc.org/articles/PMC6440078