Výsledky vyhledávání - "Daniele V.S. Lopes"

Structure–activity relationship of wedelolactone analogues: Structural requirements for inhibition of Na+,K+-ATPase and binding to the central benzodiazepine receptor

Autor: Paulo R. R. Costa, Elisa Suzana Carneiro Pôças, Chaquip D. Netto, Fernanda Leitão, Camilla D. Buarque, Paulo Henrique Cotrim Pimenta, Alcides J. M. da Silva, Flávia V. Brito, Daniele V.S. Lopes, François Noël

Publikováno v: Bioorganic & Medicinal Chemistry. 14:7962-7966

Coumestans 2a–i, bearing different patterns of substitution in A- and D-rings, were synthesized and evaluated as inhibitors of kidney Na+,K+-ATPase and ligands for the central benzodiazepine (BZP) receptor. The presence of a hydroxyl group in posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47807af4828a1bb99ac06e57bcbca6e4
https://doi.org/10.1016/j.bmc.2006.07.053

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Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor

Autor: Paulo R. R. Costa, Newton G. Castro, Rodrigo R.B. Caruso, François Noël, Daniele V.S. Lopes, Alcides J. M. da Silva

Publikováno v: European Journal of Pharmacology. 495:87-96

Research aimed at developing selective drugs acting on gamma-aminobutyric acid (GABA)A receptors introduced compounds from diverse chemical classes unrelated to the 1,4-benzodiazepines, including flavonoids. These studies also revealed the potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088980bbd80ea2636d8bd173bf5e6cb6
https://doi.org/10.1016/j.ejphar.2004.05.026

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Synthesis and preliminary pharmacological evaluation of new (±) 1,4-naphthoquinones structurally related to lapachol

Autor: Robert J. Hickey, Camilla D. Buarque, Yugo L. B. Murakami, Linda H. Malkas, Paulo A. Melo, Flávia V. Brito, Rodrigo R.B. Caruso, Laure Aurelian, Luciana Macedo, Paulo R. R. Costa, Daniele V.S. Lopes, François Noël, Noelson M.V Silva, Alcides J. M. da Silva, Newton G. Castro

Publikováno v: Bioorganic & Medicinal Chemistry. 10:2731-2738

Seven new 1,4-naphthoquinones structurally related to lapachol were synthesized from lawsone and oxygenated arylmercurials. These compounds can also be seen as pterocarpan derivatives where the A-ring was substituted by the 1,4-naphthoquinone nucleus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a43eceeca84232e5a7a043f6237ac9
https://doi.org/10.1016/s0968-0896(02)00100-1

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Pharmacokinetic Modifications and Drug-Drug Interactions in Clinical Monitoring of the Elderly: A Short Review

Autor: Gabriel Parreiras Estolano da Silveira, Daniele V.S. Lopes, Luis Eduardo M. Quintas, Karla Regina da Silva Gram, Elisa Suzana Carneiro Pôças

Publikováno v: Pharmaceutica Analytica Acta.

The combination of drugs may be a result of a necessary therapeutic strategy against a single disease or a fortuitous treatment of two or more health disorders. In either case, a consequence of such approach is the increased risk of drug interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0825739f13404678c7a2497351c0c93f
https://doi.org/10.4172/2153-2435.1000141

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Corrigendum to 'Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor' [Eur. J. Pharmacol. 495 (2004) 87–96]

Autor: Newton G. Castro, Rodrigo R.B. Caruso, Paulo R. R. Costa, Daniele V.S. Lopes, Alcides J. M. da Silva, François Noël

Publikováno v: European Journal of Pharmacology. 502:157

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9af7d6d7e7cdd7a0fd8de14a3c4571ba
https://doi.org/10.1016/j.ejphar.2004.08.029

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