Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Daniele Tauriello"'
Autor:
Alexandre Calon, Elisa Espinet, Sergio Palomo-Ponce, Daniele Tauriello, Mar Iglesias, María Céspedes, Marta Sevillano, Cristina Nadal, Peter Jung, Xiang Zhang, Daniel Byrom, Antoni Riera, David Rossell, Ramón Mangues, Joan Massague, Elena Sancho, Eduard Batlle
Publikováno v:
Bio-Protocol, Vol 4, Iss 9 (2014)
Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 accum
Externí odkaz:
https://doaj.org/article/6cc39bbe3e3440febc0c004e15972986
Autor:
Sophie Gerritse, Mariette Labots, Rob ter Heine, Henk Dekker, Dennis Poel, Daniele Tauriello, Iris Nagtegaal, Erik Van Den Hombergh, Nielka Van Erp, Henk Verheul
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6061
Cancers, 14(24):6061. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 14
Gerritse, S L, Labots, M, Heine, R T, Dekker, H, Poel, D, Tauriello, D V F, Nagtegaal, I D, van den Hombergh, E, van Erp, N & Verheul, H M W 2022, ' High-Dose Intermittent Treatment with the Multikinase Inhibitor Sunitinib Leads to High Intra-Tumor Drug Exposure in Patients with Advanced Solid Tumors ', Cancers, vol. 14, no. 24, 6061 . https://doi.org/10.3390/cancers14246061
Cancers, 14, 24
Cancers, 14(24):6061. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 14
Gerritse, S L, Labots, M, Heine, R T, Dekker, H, Poel, D, Tauriello, D V F, Nagtegaal, I D, van den Hombergh, E, van Erp, N & Verheul, H M W 2022, ' High-Dose Intermittent Treatment with the Multikinase Inhibitor Sunitinib Leads to High Intra-Tumor Drug Exposure in Patients with Advanced Solid Tumors ', Cancers, vol. 14, no. 24, 6061 . https://doi.org/10.3390/cancers14246061
Cancers, 14, 24
Patients with advanced cancer refractory to standard treatment were treated with sunitinib at a dose of 300 mg once every week (Q1W) or 700 mg once every two weeks (Q2W). Tumor, skin and plasma concentrations were measured and immunohistochemical sta