Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniele Hasler"'
Autor:
Arne Cordsmeier, Sven Rinkel, Myriam Jeninga, Jan Schulze-Luehrmann, Martha Ölke, Benedikt Schmid, Daniele Hasler, Gunter Meister, Georg Häcker, Michaela Petter, Paul A. Beare, Anja Lührmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2 (2022)
Inhibition of host cell apoptosis is crucial for survival and replication of several intracellular bacterial pathogens. To interfere with apoptotic pathways, some pathogens use specialized secretion systems to inject bacterial effector proteins into
Externí odkaz:
https://doaj.org/article/94ffbda6c9e34508bd66071b94b27c11
Autor:
Felix Grassmann, Peter G A Schoenberger, Caroline Brandl, Tina Schick, Daniele Hasler, Gunter Meister, Monika Fleckenstein, Moritz Lindner, Horst Helbig, Sascha Fauser, Bernhard H F Weber
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107461 (2014)
Age-related macular degeneration (AMD) is the leading cause of severe vision impairment in Western populations over 55 years. A growing number of gene variants have been identified which are strongly associated with an altered risk to develop AMD. Ne
Externí odkaz:
https://doaj.org/article/147f4da01aba476cb2f33a6932ac37ee
Autor:
Arne Cordsmeier, Sven Rinkel, Myriam Jeninga, Jan Schulze-Luehrmann, Martha Ölke, Benedikt Schmid, Daniele Hasler, Gunter Meister, Georg Häcker, Michaela Petter, Paul A. Beare, Anja Lührmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2 (2022)
Inhibition of host cell apoptosis is crucial for survival and replication of several intracellular bacterial pathogens. To interfere with apoptotic pathways, some pathogens use specialized secretion systems to inject bacterial effector proteins into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd272aa0d855e0ca5ec9c3f91480106
https://pubmed.ncbi.nlm.nih.gov/35134097
https://pubmed.ncbi.nlm.nih.gov/35134097
Autor:
Gunter Meister, Felix Grassmann, Bernhard H. F. Weber, Christina Kiel, Tobias Strunz, Daniele Hasler
Publikováno v:
Human molecular genetics. 31(6)
MicroRNAs (miRNAs) are small post-transcriptional regulators that offer promising targets for treating complex diseases. To this end, hsa-miR-4513 is an excellent candidate as this gene harbors within its conserved heptametrical seed sequence a frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04daf6c899d541c41ece696a5979cc50
https://pubmed.ncbi.nlm.nih.gov/34605899
https://pubmed.ncbi.nlm.nih.gov/34605899
Publikováno v:
RNA Biol
La and La-related proteins (LARPs) are characterized by a common RNA interaction platform termed the La module. This structural hallmark allows LARPs to pervade various aspects of RNA biology. The metazoan LARP7 protein binds to the 7SK RNA as part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e1d2aa60608c1d62d68c0c70388c1c
https://europepmc.org/articles/PMC7928028/
https://europepmc.org/articles/PMC7928028/
Autor:
Daniele Hasler, Gunter Meister
Publikováno v:
FEBS Letters. 590:2354-2363
Although RNA are synthesized as single-stranded molecules, most of them are characterized by extensive secondary structures. Two RNA that require distinct folding for biogenesis and function are miRNA and tRNA. While miRNA are processed from hairpin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e353de05f69424ec10138656fe158ce1
https://doi.org/10.1002/1873-3468.12294
https://doi.org/10.1002/1873-3468.12294
Autor:
Leonhard Heizinger, Eva Grauer, Rainer Merkl, Erdmute Kunstmann, Rajyalakshmi Meduri, Daniele Hasler, Utz Fischer, Reinhard Kalb, François M. Sement, Mo-Fang Liu, Gerhard Lehmann, Astrid Bruckmann, Gunter Meister, Zhi-Tong Li, Xin Wang, Mihaela Zavolan, Anne-Catherine Dock-Bregeon, Maciej Bąk
Publikováno v:
Molecular Cell. 77:1014-1031.e13
The La-related protein 7 (LARP7) forms a complex with the nuclear 7SK RNA to regulate RNA polymerase II transcription. It has been implicated in cancer and the Alazami syndrome, a severe developmental disorder. Here, we report a so far unknown role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e168287ef814173fd10486ed65352cf
https://doi.org/10.1016/j.molcel.2020.01.001
https://doi.org/10.1016/j.molcel.2020.01.001
Autor:
Nikolaus Rajewsky, Leonhard Jakob, Yasuhiro Murakawa, Gerhard Lehmann, Daniele Hasler, Markus Landthaler, Filippos Klironomos, Friedrich A. Grässer, Gunter Meister
Publikováno v:
Molecular Cell
The Lupus autoantigen La is an RNA-binding protein that stabilizes RNA polymerase III (Pol III) transcripts and supports RNA folding and has in addition been implicated in the mammalian microRNA (miRNA) pathway. Here, we have analyzed effects of La d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbcb94afb81c317e3ebec30692fb183
Autor:
Andrew J. Hamilton, Gunter Meister, Julia Alles, Norbert Eichner, Daniele Hasler, Friedrich A. Grässer, Richard Reinhardt, Linda Schlegel, Stefanie Marx, Syed Mohammad Ali Kazmi, Mathias Tesson, Joanna B. Wilson
Publikováno v:
Non-Coding RNA
Volume 1
Issue 3
Pages 170-191
Volume 1
Issue 3
Pages 170-191
The oncogenic Epstein-Barr virus (EBV) expresses 44 mature microRNAs and two non-coding EBER RNAs of 167 (EBER1) and 172 (EBER2) nt length. MiRNA profiling of NK/T cell lines and primary cells and Northern blotting of EBV-infected cell lines and prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c0316e9f28f9e4c4cc75d27bc115a9
Autor:
Jinzhong Lin, Xin Wang, Dangsheng Li, Jian-Hua Yang, Daniele Hasler, Penghui Lin, Di-Hang Lin, Jinsong Li, Wei Tang, Rajyalakshmi Meduri, Yue Yan, Ye Li, Mo-Fang Liu, Utz Fischer, Huijuan Shi, Jingyi Hui, Min-Min Hua, Gunter Meister, Hui-Tao Qi, Zhi-Tong Li
Publikováno v:
Molecular Cell. 77(5):999-1013.e6
U6 snRNA, as an essential component of the catalytic core of the pre-mRNA processing spliceosome, is heavily modified post-transcriptionally, with 2'-O-methylation being most common. The role of these modifications in pre-mRNA splicing as well as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f572cc45cf6794bf84fd6067aa74a48c