Výsledky vyhledávání - "Daniele G. Soares"

Akademický článek

Pertuzumab and trastuzumab: the rationale way to synergy

Autor: SANDRINE RICHARD, FRÉDÉRIC SELLE, JEAN-PIERRE LOTZ, AHMED KHALIL, JOSEPH GLIGOROV, DANIELE G. SOARES

Publikováno v: Anais da Academia Brasileira de Ciências, Vol 88, Iss suppl 1, Pp 565-577 (2016)

ABSTRACT It has now been 15 years since the HER2-targeted monoclonal antibody trastuzumab was introduced in clinical and revolutionized the treatment of HER2-positive breast cancer patients. Despite this achievement, most patients with HER2-positive

Externí odkaz: https://doaj.org/article/be498fc7545549b59316bd7be32b2f16

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Akademický článek

Heterophile Antibody Interference led to Unneeded Chemotherapy in a Testicular Cancer Patient

Autor: Daniele G. Soares, Françoise Millot, Isabelle Lacroix, Jean-Pierre Lotz

Publikováno v: Urology Case Reports, Vol 9, Iss C, Pp 1-3 (2016)

Human heterophile antibodies may develop after infection or contact with animal tissues or animal serum products. These antibodies have the capacity to bind to the animal immunoglobulins used in immunoassays leading to erroneous results. We here repo

Externí odkaz: https://doaj.org/article/c47b2f72cb89413abf5578c8f61e48b8

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Supplementary Figure 2 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Autor: Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares

Supplementary Figure 2 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6143b96fa93dd17df198217419a851cb
https://doi.org/10.1158/1535-7163.22497007

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Supplementary Figure 1 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Supplementary Figure 1 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a19479773794b88b98afe698935106f
https://doi.org/10.1158/1535-7163.22497010

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Supplementary Figure 3 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Supplementary Figure 3 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568fdb909bd7c8e5b8b759927c62554f
https://doi.org/10.1158/1535-7163.22497004

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Supplementary Figure 4 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Supplementary Figure 4 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a2f8057a9be951437d8ffe613851a7
https://doi.org/10.1158/1535-7163.22497001

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Data from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

PM01183 is a novel marine-derived covalent DNA binder in clinical development. PM01183 is structurally similar to trabectedin (yondelis, ecteinascidin-743) except for the C subunit, and this modification is accompanied by different pharmacokinetics i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd29afa3bcc5f8ff9581b8efc6beead0
https://doi.org/10.1158/1535-7163.c.6535465

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Genotype- or Phenotype-Targeting Anticancer Therapies? Lessons from Tumor Evolutionary Biology

Autor: Alexandre E. Escargueil, Soizic Prado, Daniele G. Soares, Ambre Dezaire, Jean Clairambault, Annette K. Larsen

Publikováno v: Current Pharmaceutical Design. 22:6625-6644

Despite the efficacy of most cancer therapies, drug resistance remains a major problem in the clinic. The eradication of the entire tumor and the cure of the patient by chemotherapy alone are rare, in particular for advanced disease. From an evolutio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26774946d15318637d75ba96cbe727c
https://doi.org/10.2174/1381612822666160831114002

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Trabectedin for sarcomas in daily clinical practice: analysis of 45 patients treated in a French institution

Autor: Julie Fillon, Daniele G. Soares, Pascal Paubel, Isabelle Debrix, Jean-Pierre Lotz, Johanne Daupin

Publikováno v: Journal of Chemotherapy. 28:494-499

The active clinical research programme of trabectedin continues to improve knowledge on the therapeutic activity and toxicity of the drug in the treatment of soft tissue sarcomas (STS). In contrast, limited number of data is available on its use outs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9ece94bb7c6dcabe9fe8284d8d5a96
https://doi.org/10.1080/1120009x.2016.1218179

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