Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daniele Borin"'
Autor:
Ambra Cappelletto, Edoardo Alfì, Nina Volf, Thi Van Anh Vu, Francesca Bortolotti, Giulio Ciucci, Simone Vodret, Marco Fantuz, Martina Perin, Andrea Colliva, Giacomo Rozzi, Matilde Rossi, Giulia Ruozi, Lorena Zentilin, Roman Vuerich, Daniele Borin, Romano Lapasin, Silvano Piazza, Mattia Chiesa, Daniela Lorizio, Luca Triboli, Sandeep Kumar, Gaia Morello, Claudio Tripodo, Maurizio Pinamonti, Giulia Maria Piperno, Federica Benvenuti, Alessandra Rustighi, Hanjoong Jo, Stefano Piccolo, Giannino Del Sal, Alessandro Carrer, Mauro Giacca, Serena Zacchigna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background New drugs to tackle the next pathway or mutation fueling cancer are constantly proposed, but 97% of them are doomed to fail in clinical trials, largely because they are identified by cellular or in silico screens that cannot predi
Externí odkaz:
https://doaj.org/article/a789156b8a0b44008d091dcfb970d332
Autor:
Daniele Borin, Brisa Peña, Suet Nee Chen, Carlin S. Long, Matthew R.G. Taylor, Luisa Mestroni, Orfeo Sbaizero
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03175- (2020)
Given the clinical effect of laminopathies, understanding lamin mechanical properties will benefit the treatment of heart failure. Here we report a mechano-dynamic study of LMNA mutations in neonatal rat ventricular myocytes (NRVM) using single cell
Externí odkaz:
https://doaj.org/article/9cbdabc3c9904adda2f3bcea6b9a1b73
Publikováno v:
Cells, Vol 6, Iss 4, p 33 (2017)
Lamins are type V intermediate filaments that collectively form a meshwork underneath the inner nuclear membrane, called nuclear lamina. Furthermore, they are also present in the nucleoplasm. Lamins are experiencing a growing interest, since a wide r
Externí odkaz:
https://doaj.org/article/27b2e554e1454163a0eefe9f17a543e0
Autor:
Brisa Peña, Shanshan Gao, Daniele Borin, Giorgia Del Favero, Mostafa Abdel-Hafiz, Nasim Farahzad, Paola Lorenzon, Gianfranco Sinagra, Matthew R. G. Taylor, Luisa Mestroni, Orfeo Sbaizero
Given the clinical effect of progeria syndrome, understanding the cell mechanical behavior of this pathology could benefit the patient's treatment. Progeria patients show a point mutation in the lamin A/C gene (LMNA), which could change the cell's bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d107f8896c75e57d0475f26e4dedc1c
https://hdl.handle.net/11368/3034885
https://hdl.handle.net/11368/3034885
Autor:
Luisa Mestroni, Daniele Borin, Romano Lapasin, Orfeo Sbaizero, Matthew R.G. Taylor, Brisa Peña
Publikováno v:
Biorheology. 57(1)
BACKGROUND: Laminopathies are genetic diseases caused by mutations in the nuclear lamina. OBJECTIVE: Given the clinical impact of laminopathies, understanding mechanical properties of cells bearing lamin mutations will lead to advancement in the trea
Autor:
Carlin S. Long, Matthew R.G. Taylor, Luisa Mestroni, Daniele Borin, Orfeo Sbaizero, Brisa Peña, Suet Nee Chen
Publikováno v:
Heliyon, vol 6, iss 1
Heliyon, Vol 6, Iss 1, Pp e03175-(2020)
Heliyon
Heliyon, Vol 6, Iss 1, Pp e03175-(2020)
Heliyon
Given the clinical effect of laminopathies, understanding lamin mechanical properties will benefit the treatment of heart failure. Here we report a mechano-dynamic study of LMNA mutations in neonatal rat ventricular myocytes (NRVM) using single cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cec31159ae62f6eb78135bb9b902f64
https://escholarship.org/uc/item/7q20s44p
https://escholarship.org/uc/item/7q20s44p
Autor:
Flavia Liotta, Marco Torre, Valerio Paolini, Daniele Borin, Laura Tomassetti, Francesco Petracchini, Marco Segreto
Publikováno v:
Journal of Material Cycles and Waste Management. 21:205-226
The use of asbestos was banned because of the carcinogenic properties of its fibres, but asbestos-containing wastes are still present in great amounts. They are currently landfilled or encapsulated with resins, but these approaches led to the release
Autor:
Priyatansh Gurha, Luisa Mestroni, Daniele Borin, Laura Andolfi, Luca Puzzi, Valentina Martinelli, Marek Weiss, Raffaella Lombardi, Orfeo Sbaizero, Ali J. Marian, Marco Lazzarino
Publikováno v:
Cells
Volume 8
Issue 12
Cells 8 (2019). doi:10.3390/cells8121639
info:cnr-pdr/source/autori:Puzzi L.; Borin D.; Gurha P.; Lombardi R.; Martinelli V.; Weiss M.; Andolfi L.; Lazzarino M.; Mestroni L.; Marian A.J.; Sbaizero O./titolo:Knock Down of Plakophillin 2 Dysregulates Adhesion Pathway through Upregulation of miR200b and Alters the Mechanical Properties in Cardiac Cells/doi:10.3390%2Fcells8121639/rivista:Cells/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Volume 8
Issue 12
Cells 8 (2019). doi:10.3390/cells8121639
info:cnr-pdr/source/autori:Puzzi L.; Borin D.; Gurha P.; Lombardi R.; Martinelli V.; Weiss M.; Andolfi L.; Lazzarino M.; Mestroni L.; Marian A.J.; Sbaizero O./titolo:Knock Down of Plakophillin 2 Dysregulates Adhesion Pathway through Upregulation of miR200b and Alters the Mechanical Properties in Cardiac Cells/doi:10.3390%2Fcells8121639/rivista:Cells/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Background: Mutations in genes encoding intercalated disk/desmosome proteins, such as plakophilin 2 (PKP2), cause arrhythmogenic cardiomyopathy (ACM). Desmosomes are responsible for myocyte&ndash
myocyte attachment and maintaining mechanical int
myocyte attachment and maintaining mechanical int
This study address issues specifically related to the underwater dynamic actuation of Micro Electro Mechanical Systems (MEMS), such as micro-cantilevers or comb-drive microstructures. As a practical application, cantilevers made using MUMPs (Multi-Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c0db5cc9704dbf4e9752a5857d8b72
https://hdl.handle.net/11368/2928625
https://hdl.handle.net/11368/2928625
Autor:
Valentina Martinelli, David P. Kelsell, Luca Puzzi, Luisa Mestroni, Orfeo Sbaizero, Daniele Borin
Publikováno v:
Micron (Oxford, England : 1993). 106
In a tissue continuously challenged by mechanical stresses, such as the skin or the heart, cells perceive information about their microenvironment through several adhesive protein complexes and activate cell-signaling events to maintain tissue cohesi