The interplay of polar effects in controlling the selectivity of radical reactions

Autor: Alessandro Ruffoni, Rory C. Mykura, Massimo Bietti, Daniele Leonori

Publikováno v: Nature Synthesis. 1:682-695

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::003723c8e810a5c6c90a9cb9e213bd39
https://doi.org/10.1038/s44160-022-00108-2

Dualkatalytisch‐Photochemische H‐Atomtransfer/Kobaltkatalysesequenz Ermöglicht Desaturative Synthese von Phenolen aus Cyclohexanonen

Autor: Henry P. Caldora, Zhenhua Zhang, Michael J. Tilby, Oliver Turner, Daniele Leonori

Publikováno v: Angewandte Chemie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1750d23484e76b68075c0763ce1d41de
https://doi.org/10.1002/ange.202301656

Halogen-atom and group transfer reactivity enabled by hydrogen tunneling

Autor: Timothée Constantin, Bartosz Górski, Michael J. Tilby, Saloua Chelli, Fabio Juliá, Josep Llaveria, Kevin J. Gillen, Hendrik Zipse, Sami Lakhdar, Daniele Leonori

Publikováno v: Constantin, T, Górski, B, Tilby, M J, Chelli, S, Julia Hernandez, F, Llaveria, J, Gillen, K J, Zipse, H, Lakhdar, S & Leonori, D 2022, ' Halogen-atom and group transfer reactivity enabled by hydrogen tunneling ', Science, vol. 377, no. 6612, pp. 1323-1328 . https://doi.org/10.1126/science.abq8663

The generation of carbon radicals by halogen-atom and group transfer reactions is generally achieved using tin and silicon reagents that maximize the interplay of enthalpic (thermodynamic) and polar (kinetic) effects. In this work, we demonstrate a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3301b3ec6f06db1972c7df507ce3713
https://pubmed.ncbi.nlm.nih.gov/36108027

A de novo Synthesis of Oxindoles from Cyclohexanone-Derived γ-Keto-Ester Acceptors Using a Desaturative Amination–Cyclization Approach

Autor: Sebastian Govaerts, Shashikant U. Dighe, Daniele Leonori, Oliver J. Turner, Henry P. Caldora

Publikováno v: Synthesis. 53:4272-4278

Here we report a desaturative approach for oxindole synthesis. This method uses simple ethyl 2-(2-oxocyclohexyl)acetates and primary amine building blocks as coupling partners. A dual photoredox–cobalt manifold is used to generate a secondary anili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9267b95bccf851b6cce81957f375a7c9
https://doi.org/10.1055/a-1538-8429

Photoexcited Nitroarenes as Ozone Surrogates for the Oxidative Cleavage of Olefins

Autor: Daniele Leonori, Alessandro Ruffoni, Charlotte Hampton, Marco Simonetti

The oxidative cleavage of olefins is an integral process that converts feedstocks into high-value synthetic intermediates , , . The most viable method to oxidatively cleave C–Cπ bonds in one chemical step is with ozone , , , , which however poses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::717066b9b9dc82499d5a58351b60f22b
https://doi.org/10.21203/rs.3.rs-1590024/v1