Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Daniele, Castiglia"'
Autor:
David Rafei-Shamsabadi, Lena Scholten, Sisi Lu, Daniele Castiglia, Giovanna Zambruno, Andreas Volz, Andreas Arnold, Mina Saleva, Ludovic Martin, Kristin Technau-Hafsi, Frank Meiss, Dagmar von Bubnoff, Cristina Has
Publikováno v:
Cancers, Vol 16, Iss 2, p 471 (2024)
Cutaneous squamous cell carcinomas (SCCs) are a major complication of some subtypes of epidermolysis bullosa (EB), with high morbidity and mortality rates and unmet therapeutic needs. The high rate of endogenous mutations and the fibrotic stroma are
Externí odkaz:
https://doaj.org/article/6e339ea26d1f4696b82411888b77f516
Autor:
Elena Dellambra, Sonia Cordisco, Francesca Delle Monache, Sergio Bondanza, Massimo Teson, Ezio Maria Nicodemi, Biagio Didona, Angelo Giuseppe Condorelli, Giovanna Camerino, Daniele Castiglia, Liliana Guerra
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-20 (2022)
Abstract Background Secreted R-spondin (RSPO) proteins play a key role in reproductive organ development, epithelial stem cell renewal and cancer induction by reinforcing canonical Wnt signaling. We have previously reported that palmoplantar keratode
Externí odkaz:
https://doaj.org/article/b8e473838ba44368bd41b054eff3bdac
Autor:
Damiano Abeni, Roberta Rotunno, Andrea Diociaiuti, Simona Giancristoforo, Domenico Bonamonte, Carmelo Schepis, Iria Neri, Daniele Castiglia, Giovanna Zambruno, May El Hachem
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Autosomal recessive congenital ichthyoses (ARCI) are a genetically heterogeneous group of rare and chronic disorders characterized by generalized skin scaling and hyperkeratosis, erythroderma, and palmoplantar keratoderma. Additio
Externí odkaz:
https://doaj.org/article/d79a0697e9b94a8baa22205810a3a020
Autor:
Giovanni Di Zenzo, Giovanna Floriddia, Sabrina Rossi, Feliciana Mariotti, Alessia Primerano, Angelo Giuseppe Condorelli, Biagio Didona, Daniele Castiglia
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmune response to cutaneous basement membrane components superimposed on a genetic skin fragility disease, hereditary epidermolysis bullosa (EB), has been described, but its effects on disease course remain unclear. We report a 69-year-old indiv
Externí odkaz:
https://doaj.org/article/3d4e38c3a6ce4243ab9e27c11bca0a40
Autor:
Angelo Giuseppe Condorelli, May El Hachem, Giovanna Zambruno, Alexander Nystrom, Eleonora Candi, Daniele Castiglia
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Fibrosis can be defined as an excessive and deregulated deposition of extracellular matrix proteins, causing loss of physiological architecture and dysfunction of different tissues and organs. In the skin, fibrosis represents the hallmark of
Externí odkaz:
https://doaj.org/article/edf4e354c14449f8876a72aac3b5aa23
Autor:
Enrico Scala, Stefania Madonna, Daniele Castiglia, Alessandro Scala, Elisabetta Caprini, Roberto Paganelli
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 202 (2023)
(1) Background: Atopic dermatitis constitutes one of the most common inflammatory skin manifestations of the pediatric population. The onset of many inborn errors occurs early in life with an AD–like picture associated with a deregulated IgE respon
Externí odkaz:
https://doaj.org/article/d4f73b605f3e49e688b2a13825ab3a8e
Autor:
Damiano Abeni, Roberta Rotunno, Andrea Diociaiuti, Simona Giancristoforo, Domenico Bonamonte, Angela Filoni, Carmelo Schepis, Maddalena Siragusa, Iria Neri, Annalucia Virdi, Daniele Castiglia, Giovanna Zambruno, Christine Bodemer, May El Hachem
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 6, p adv00477 (2021)
Autosomal recessive congenital ichthyoses (ARCI) are characterized by generalized skin scaling, hyperkeratosis, erythroderma, and disabling features affecting the skin (palmoplantar keratoderma, fissures, pain, itch), eyes, ears, and joints. Disease
Externí odkaz:
https://doaj.org/article/f436a179d79c40c4aee9aec604ea082f
Autor:
Sara Guerrero-Aspizua, Claudio J. Conti, Maria Jose Escamez, Daniele Castiglia, Giovanna Zambruno, Leila Youssefian, Hassan Vahidnezhad, Luis Requena, Peter Itin, Gianluca Tadini, Ivelina Yordanova, Ludovic Martin, Jouni Uitto, Cristina Has, Marcela Del Rio
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-15 (2019)
Abstract Background Kindler Syndrome (KS) is a rare genodermatosis characterized by skin fragility, skin atrophy, premature aging and poikiloderma. It is caused by mutations in the FERMT1 gene, which encodes kindlin-1, a protein involved in integrin
Externí odkaz:
https://doaj.org/article/2039cab014194ad7a6c6aa5ac424b587
Autor:
Andrea Diociaiuti, Roberta Caruso, Silvia Ricci, Rita De Vito, Luisa Strocchio, Daniele Castiglia, Giovanna Zambruno, May El Hachem
Publikováno v:
Genes, Vol 13, Iss 5, p 821 (2022)
Multiple intestinal atresia with combined immune deficiency (MIA-CID) is an autosomal recessive syndrome due to mutations in the TTC7A gene implicated in the polarization of intestinal and thymic epithelial cells. MIA-CID is lethal in the first year
Externí odkaz:
https://doaj.org/article/643ae9a0c1a142a0b6bea7852acd00d2
Autor:
Liliana Guerra, Angelo Giuseppe Condorelli, Paola Fortugno, Valentina Calabresi, Cristina Pedicelli, Giovanni Di Zenzo, Daniele Castiglia
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 4, Pp 411-415 (2018)
Circulating anti-type VII collagen autoantibodies are frequently detected in patients with recessive dystrophic epidermolysis bullosa (RDEB). However, evidence supporting their pathogenic role in inducing epidermolysis bullosa acquisita (EBA) has bee
Externí odkaz:
https://doaj.org/article/5d36889c2e6443a399d70a01fe69befe