Výsledky vyhledávání - "Daniela-Lee Smith"

Crosstalk of Phosphorylation and Arginine Methylation in Disordered SRGG Repeats of Saccharomyces cerevisiae Fibrillarin and Its Association with Nucleolar Localization

Autor: Yu-Wen Lai, Melissa A. Erce, Daniela-Lee Smith, Joshua J. Hamey, Marc R. Wilkins, Gene Hart-Smith, Florence Tomasetig

Publikováno v: Journal of Molecular Biology. 432:448-466

Crosstalk exists when two or more post-translational modifications, nearby in sequence or 3D space, affect each other or a protein's interactions. Saccharomyces cerevisiae protein Npl3p has six repeats of sequence SRGG, in a disordered domain, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5774c4d82d4bebd1da65b20ce7257e05
https://doi.org/10.1016/j.jmb.2019.11.006

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Characterization of the Interaction between Arginine Methyltransferase Hmt1 and Its Substrate Npl3: Use of Multiple Cross-Linkers, Mass Spectrometric Approaches, and Software Platforms

Autor: Marc R. Wilkins, Gene Hart-Smith, Daniela Lee Smith, Michael Götze, Tara K. Bartolec

Publikováno v: Analytical Chemistry. 90:9101-9108

This study investigated the enzyme-substrate interaction between Saccharomyces cerevisiae arginine methyltransferase Hmt1p and nucleolar protein Npl3p, using chemical cross linking/mass spectrometry (XL/MS). We show that XL/MS can capture transient i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe5319edd259f0c7256f22522ba490f
https://doi.org/10.1021/acs.analchem.8b01525

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Cross-linking Mass Spectrometry Analysis of the Yeast Nucleus Reveals Extensive Protein-Protein Interactions Not Detected by Systematic Two-Hybrid or Affinity Purification-Mass Spectrometry

Autor: Chi Nam Ignatius Pang, Joshua J. Hamey, Daniela-Lee Smith, You Dan Xu, Tara K. Bartolec, Marc R. Wilkins

Publikováno v: Analytical chemistry. 92(2)

Saccharomyces cerevisiae has the most comprehensively characterized protein-protein interaction network, or interactome, of any eukaryote. This has predominantly been generated through multiple, systematic studies of protein-protein interactions by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf78c828ee3e0147616296af14028dc
https://pubmed.ncbi.nlm.nih.gov/31851481

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Dynamics of archaea at fine spatial scales in Shark Bay mat microbiomes

Autor: Hon Lun Wong, Daniela Lee Smith, Brendan P. Burns, Pieter T. Visscher, Richard A. White, Molly M. Patterson

Publikováno v: Scientific Reports

The role of archaea in microbial mats is poorly understood. Delineating the spatial distribution of archaea with mat depth will enable resolution of putative niches in these systems. In the present study, high throughput amplicon sequencing was under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5d22f41eafd609f31d5870ffe5e7a3
https://pubmed.ncbi.nlm.nih.gov/28397816

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Niche differentiation of bacterial communities at a millimeter scale in Shark Bay microbial mats

Autor: Brendan P. Burns, Hon Lun Wong, Daniela-Lee Smith, Pieter T. Visscher

Publikováno v: Scientific Reports

Modern microbial mats can provide key insights into early Earth ecosystems and Shark Bay, Australia, holds one of the best examples of these systems. Identifying the spatial distribution of microorganisms with mat depth facilitates a greater understa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f82a88002e6c9668fc0cfcdbc992503
https://doi.org/10.1038/srep15607

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