Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Daniela- Elena COSTEA"'
Autor:
Irina IVASIUC, Marina MARKARYAN, Gayane MANRIKYAN, Natalia SHACAVETS, Simion LEVCO, Mikayel MANRIKYAN, Izabella VARDANYAN, Tatiana MARIȚOI, Olga CHEPTĂNARU, Daniela- Elena COSTEA, Diana UNCUȚA
Publikováno v:
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, Vol 74, Iss 3, Pp 212-215 (2022)
Lichen plan oral este o afecțiune cronică, mucocutanată cu o etiologie needentificată. Cel mai mult sunt afectate femeile cu vârsta cuprinsă între 30 și 60 ani. Rata incidenței pe întreaga populație este de 1-2%. Tipic sunt prezente leziun
Externí odkaz:
https://doaj.org/article/51e105cb99d847c4919543732f867bc6
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Tumor microenvironment (TME) in head and neck squamous cell carcinoma (HNSCC) has a major influence on disease progression and therapy response. One of the predominant stromal cell types in the TME of HNSCC is cancer-associated fibroblasts (CAF). CAF
Externí odkaz:
https://doaj.org/article/85f55e3b6b4247de968162454eeb2d1c
Autor:
Stian Tornaas, Dimitrios Kleftogiannis, Siren Fromreide, Hilde Ytre-Hauge Smeland, Hans Jørgen Aarstad, Olav Karsten Vintermyr, Lars Andreas Akslen, Daniela Elena Costea, Harsh Nitin Dongre
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31191- (2024)
To decipher the interactions between various components of the tumor microenvironment (TME) and tumor cells in a preserved spatial context, a multiparametric approach is essential. In this pursuit, imaging mass cytometry (IMC) emerges as a valuable t
Externí odkaz:
https://doaj.org/article/6344f46aeae6447b80fe879f9f1b0eb1
Autor:
Nuha Mohamed Gaafar, Tarig Al‐Hadi Osman, Israa Abdulrahman Ahmed, Mariam Elsheikh, Harsh Dongre, Martha Rolland Jacobsen, Nazar Gafar Mohamed, Siren Fromreide, Ahmed Mohamed Suleiman, Anne Christine Johannessen, Elisabeth Sivy Nginamau, Daniela Elena Costea
Publikováno v:
Clinical and Experimental Dental Research, Vol 8, Iss 1, Pp 130-140 (2022)
Abstract Background Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor compartments are limit
Externí odkaz:
https://doaj.org/article/9898f1568ef7490eae6ab44921d4f1f0
Autor:
Olga Golburean, Maria Helene Hagen, Diana Uncuta, Marcela Tighineanu, Gayane Manrikyan, Izabella Vardanian, Christoffer Andresen, Bhavdeep Singh, Tatiana Porosencova, Irina Ivasiuc, Olga Cheptanaru, Marina Markaryan, Natalia Shakavets, Dipak Sapkota, Tine Merete Søland, Daniela-Elena Costea, Ferda Özkaya
Publikováno v:
BMC Oral Health, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Introduction Moldova, Belarus, and Armenia are post-Soviet countries with a high rate of heavy smokers and a relatively high age-standardized incidence of oral cancer. However, to our knowledge, there is lack of available information on dent
Externí odkaz:
https://doaj.org/article/c1474777eb674e978b71c19b59a40568
Autor:
Toshinori Ando, Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto, Hiroki Izumi, Mara Gilardi, Kazuyo Ando, J. Silvio Gutkind
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Ando et al show in head and neck squamous cell carcinoma cells that EGFR activation leads to the phosphorylation of the Hippo pathway component, MOB1 to inhibit LATS1/2 function resulting in YAP/TAZ activation. Further, EGFR-targeting therapies suppr
Externí odkaz:
https://doaj.org/article/33b5d7dcaf814e90908b2ebbb399a0ea
Autor:
Saroj Rajthala, Himalaya Parajuli, Harsh Nitin Dongre, Borghild Ljøkjel, Kristin Marie Hoven, Arild Kvalheim, Stein Lybak, Evelyn Neppelberg, Dipak Sapkota, Anne Christine Johannessen, Daniela-Elena Costea
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundRecent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its effects on their phenotype and
Externí odkaz:
https://doaj.org/article/e236d4ae072346949a40c53dad1e9d29
Autor:
Siddharth Shanbhag, Carina Kampleitner, Samih Mohamed-Ahmed, Mohammed Ahmad Yassin, Harsh Dongre, Daniela Elena Costea, Stefan Tangl, Mohamad Nageeb Hassan, Andreas Stavropoulos, Anne Isine Bolstad, Salwa Suliman, Kamal Mustafa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/6e4b7b04d07f4cc0be432d55cddba478
Autor:
Siddharth Shanbhag, Carina Kampleitner, Samih Mohamed-Ahmed, Mohammed Ahmad Yassin, Harsh Dongre, Daniela Elena Costea, Stefan Tangl, Mohamad Nageeb Hassan, Andreas Stavropoulos, Anne Isine Bolstad, Salwa Suliman, Kamal Mustafa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative to bone marrow MSC (BMS
Externí odkaz:
https://doaj.org/article/7b861d5063464b59953b67ae6b61b238
Autor:
Irina Ivasiuc, Marina Markaryan, Gayane Manrikyan, Natalia Shacavets, Simion Levco, Mikayel Manrikyan, Izabella Vardanyan, Tatiana Maritoi, Olga Cheptanaru, Daniela-Elena Costea, Diana Uncuta
Publikováno v:
Bulletin of the Academy of Sciences of Moldova. Medical Sciences. 74:212-215
Oral lichen planus is a chronic, mucocutaneous condition with an unidentified etiology. Women between the ages of 30 and 60 are most affected. The incidence rate for the entire population is 1-2%. Bilateral lesions are typically whitish, sometimes ul